Search Results - "ROGALSKI, T. M"
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Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan
Published in Genes & development (01-08-1993)“…Mutations in the unc-52 gene of Caenorhabditis elegans affect attachment of the myofilament lattice to the muscle cell membrane. Here, we demonstrate that the…”
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Mutations in the unc-52 Gene Responsible for Body Wall Muscle Defects in Adult Caenorhabditis elegans Are Located in Alternatively Spliced Exons
Published in Genetics (Austin) (01-01-1995)“…The unc-52 gene in Caenorhabditis elegans produces several large proteins that function in the basement membrane underlying muscle cells. Mutations in this…”
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The UNC-112 Gene in Caenorhabditis elegans Encodes a Novel Component of Cell-Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane
Published in The Journal of cell biology (10-07-2000)“…Embryos homozygous for mutations in the unc-52, pat-2, pat-3, and unc-112 genes of C. elegans exhibit a similar Pat phenotype. Myosin and actin are not…”
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The unc-22(IV) Region of Caenorhabditis elegans: Genetic Analysis of Lethal Mutations
Published in Genetics (Austin) (01-06-1988)“…The organization of essential genes in the unc-22 region, defined by the deficiency sDf2 on linkage group IV, has been studied. Using the balancer nT1 (IV;V),…”
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A Caenorhabditis elegans RNA Polymerase II Gene, ama-1 IV, and Nearby Essential Genes
Published in Genetics (Austin) (01-01-1988)“…The amanitin-binding subunit of RNA polymerase II in Caenorhabditis elegans is encoded by the ama-1 gene, located approximately 0.05 map unit to the right of…”
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Lethal and Amanitin-Resistance Mutations in the Caenorhabditis elegans ama-1 and ama-2 Genes
Published in Genetics (Austin) (01-10-1988)“…Mutants of Caenorhabditis elegans resistant to alpha-amanitin have been isolated at a frequency of about 1.6 x 10(-6) after EMS mutagenesis of the wild-type…”
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Mutant Caenorhabditis elegans RNA polymerase II with a 20,000-fold reduced sensitivity to alpha-amanitin
Published in Genetics (Austin) (01-12-1990)“…A doubly mutant ama-1(m118m526) gene results in an RNA polymerase (Rpo) II that is unusually resistant to alpha-amanitin. Rpo II activity in isolated…”
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Post-Transcriptional Regulation of RNA Polymerase II Levels in Caenorhabditis elegans
Published in Genetics (Austin) (01-02-1993)“…To investigate the regulation of RNA polymerase II levels in Caenorhabditis elegans, we have constructed nematode strains having one, two, or three copies of…”
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Complex patterns of alternative splicing mediate the spatial and temporal distribution of perlecan/UNC-52 in Caenorhabditis elegans
Published in Molecular biology of the cell (01-10-1999)“…The unc-52 gene encodes the nematode homologue of mammalian perlecan, the major heparan sulfate proteoglycan of the extracellular matrix. This is a large…”
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UNC-52/perlecan isoform diversity and function in Caenorhabditis elegans
Published in Biochemical Society transactions (01-05-2001)“…The unc-52 gene encodes the nematode homologue of mammalian perlecan, the major heparan sulphate proteoglycan of the extracellular matrix. This is a large…”
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The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts
Published in Development (Cambridge) (01-05-1996)“…Mutations in the mec-8 gene of Caenorhabditis elegans were previously shown to affect the functions of body wall muscle and mechanosensory and chemosensory…”
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ESSENTIAL GENES AND DEFICIENCIES IN THE UNC-22 IV REGION OF CAENORHABDITIS ELEGANS
Published in Genetics (Austin) (01-12-1982)“…Five formaldehyde-induced deficiencies that uncover unc-22 IV, a gene affecting muscle structure in the nematode Caenorhabditis elegans were isolated and…”
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Genetic organization of the unc-22 IV gene and the adjacent region in Caenorhabditis elegans
Published in Molecular & general genetics (1985)“…The genetic organization of the region immediately adjacent to the unc-22 IV gene in Caenorhabditis elegans has been studied. We have identified twenty…”
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DIM-1, a Novel Immunoglobulin Superfamily Protein in Caenorhabditis elegans, Is Necessary for Maintaining Bodywall Muscle Integrity
Published in Genetics (Austin) (01-03-2003)“…The UNC-112 protein is required during initial muscle assembly in C. elegans to form dense bodies and M-lines. Loss of this protein results in arrest at the…”
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Mutant Caenorhabditis elegans RNA Polymerase II With a 20,000-Fold Reduced Sensitivity to {alpha}-Amanitin
Published in Genetics (Austin) (01-12-1990)Get full text
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