Search Results - "ROFFE, Christine"

Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study by Perry, Richard J, Tamborska, Arina, Singh, Bhagteshwar, Craven, Brian, Marigold, Richard, Arthur-Farraj, Peter, Yeo, Jing Ming, Zhang, Liqun, Hassan-Smith, Ghaniah, Jones, Matthew, Hutchcroft, Christopher, Hobson, Esther, Warcel, Dana, White, Daniel, Ferdinand, Phillip, Webb, Alastair, Solomon, Tom, Scully, Marie, Werring, David J, Roffe, Christine, Al-izzi, Sara, Baheerathan, Aravindhan, Banerjee, Soma, Benson, Gary, Boshier, Claudia, Buddha, Sandeep, Burley, Nathan, Cameron Smail, Ruaridh, Chandratheva, Arvind, Chudakou, Pavel, Clatworthy, Philip, Coles, Alasdair, Cox, Thomas, Dasgupta, Ranjit, Davenport, Richard, Devine, Darrell, Fenlon, Stephen, Gabriel, Carolyn, Ghatala, Rita, Hall, Claire, Hargovan, Milan, Harkness, Kirsty, Harvey, Ian, Hicken, Lucy, Howaniec, Laura, Ibnouf, Abubaker, Idrovo, Luis, Ingle, Gordon, Kyan Lee, Yong, Lang, Ailidh, McBride, Simon, McLeod, Malcolm, Medlock, Ruth, Mehta, Puja, Morrison, Ian, Muddegowda, Girish, Muzerengi, Sharon, Pang, Donald, Periyasamy, Gopinath, Preston, Gavin, Priestley, Naomi, Revicka, Lydia, Saber, Sadia, Smith, Elliott, Sorour, Youssef, Spooner, Oliver, Stone, Jon, Sztriha, Laszlo, Thambirajah, Narmathey, Thomas, Rhys, Veale, David, Wall, Jasmine, White, Sarah, White, James, Yusoff, Syarah, Zambreanu, Laura

“…A new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous…”
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Early Diagnosis of Pneumonia in Severe Stroke: Clinical Features and the Diagnostic Role of C-Reactive Protein by Warusevitane, Anushka, Karunatilake, Dumin, Sim, Julius, Smith, Craig, Roffe, Christine

“…Accurate diagnosis of pneumonia complicating severe stroke is challenging due to difficulties in physical examination, altered immune responses and delayed…”
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Post-stroke dysphagia: A review and design considerations for future trials by Cohen, David L, Roffe, Christine, Beavan, Jessica, Blackett, Brenda, Fairfield, Carol A, Hamdy, Shaheen, Havard, Di, McFarlane, Mary, McLauglin, Carolee, Randall, Mark, Robson, Katie, Scutt, Polly, Smith, Craig, Smithard, David, Sprigg, Nikola, Warusevitane, Anushka, Watkins, Caroline, Woodhouse, Lisa, Bath, Philip M

“…Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased…”
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Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke) by Barreto, Andrew D, Ford, Gary A, Shen, Loren, Pedroza, Claudia, Tyson, Jon, Cai, Chunyan, Rahbar, Mohammad H, Grotta, James C

“…We conducted a randomized exploratory study to assess safety and the probability of a favorable outcome with adjunctive argatroban, a direct…”
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The stroke oxygen pilot study: a randomized controlled trial of the effects of routine oxygen supplementation early after acute stroke--effect on key outcomes at six months by Ali, Khalid, Warusevitane, Anushka, Lally, Frank, Sim, Julius, Sills, Sheila, Pountain, Sarah, Nevatte, Tracy, Allen, Martin, Roffe, Christine

“…Post-stroke hypoxia is common, and may adversely affect outcome. We have recently shown that oxygen supplementation may improve early neurological recovery…”
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Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT by Watkins, Caroline, Tishkovskaya, Svetlana, Brown, Chris, Sutton, Chris, Garcia, Yvonne Sylvestre, Forshaw, Denise, Prescott, Gordon, Thomas, Lois, Roffe, Christine, Booth, Joanne, Bennett, Kina, Roe, Brenda, Hollingsworth, Bruce, Mateus, Ceu, Britt, David, Panton, Cliff

“…Urinary incontinence affects around half of stroke survivors in the acute phase, and it often presents as a new problem after stroke or, if pre-existing,…”
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Validation and Recalibration of Two Multivariable Prognostic Models for Survival and Independence in Acute Stroke by Sim, Julius, Teece, Lucy, Dennis, Martin S, Roffe, Christine

“…Various prognostic models have been developed for acute stroke, including one based on age and five binary variables ('six simple variables' model; SSVMod) and…”
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Can Surface Neuromuscular Electrical Stimulation of the Wrist and Hand Combined With Routine Therapy Facilitate Recovery of Arm Function in Patients With Stroke? by Rosewilliam, Sheeba, MSc, Malhotra, Shweta, MSc, Roffe, Christine, MD, Jones, Peter, PhD, Pandyan, Anand D., PhD

“…Abstract Rosewilliam S, Malhotra S, Roffe C, Jones P, Pandyan AD. Can surface neuromuscular electrical stimulation of the wrist and hand combined with routine…”
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Management of Acute Stroke in the Older Person by Parr, Emma, Ferdinand, Phillip, Roffe, Christine

“…The majority of people who suffer a stroke are older adults. The last two decades have brought major progress in the diagnosis and management of stroke, which…”
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A randomized controlled trial of surface neuromuscular electrical stimulation applied early after acute stroke: effects on wrist pain, spasticity and contractures by Malhotra, Shweta, Rosewilliam, Sheeba, Hermens, Hermie, Roffe, Christine, Jones, Peter, Pandyan, Anand David

“…Objectives: To investigate effects of surface neuromuscular electrical stimulation applied early after stroke to the wrist and finger extensor muscles on upper…”
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Routine low-dose continuous or nocturnal oxygen for people with acute stroke: three-arm Stroke Oxygen Supplementation RCT by Roffe, Christine, Nevatte, Tracy, Bishop, Jon, Sim, Julius, Penaloza, Cristina, Jowett, Susan, Ives, Natalie, Gray, Richard, Ferdinand, Phillip, Muddegowda, Girish

“…Stroke is a major cause of death and disability worldwide. Hypoxia is common after stroke and is associated with worse outcomes. Oxygen supplementation could…”
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Does low-dose botulinum toxin help the recovery of arm function when given early after stroke? A phase II randomized controlled pilot study to estimate effect size by Cousins, Elizabeth, Ward, Anthony, Roffe, Christine, Rimington, Lesley, Pandyan, Anand

“…Objective: Spasticity after stroke may be associated with worse functional outcome. Our study aim is to establish whether a low dose of botulinum toxin, given…”
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Is intraprocedural intravenous aspirin safe for patients who require emergent extracranial stenting during mechanical thrombectomy? by Ingleton, Adam, Raseta, Marko, Chung, Rui-En, Kow, Kevin Jun Hui, Weddell, Jake, Nayak, Sanjeev, Jadun, Changez, Hashim, Zafar, Qayyum, Noman, Ferdinand, Phillip, Natarajan, Indira, Roffe, Christine

“…BackgroundIntraoperative antiplatelet therapy is recommended for emergent stenting during mechanical thrombectomy (MT). Most patients undergoing MT are also…”
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Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT by Sprigg, Nikola, Flaherty, Katie, Appleton, Jason P, Al-Shahi Salman, Rustam, Bereczki, Daniel, Beridze, Maia, Ciccone, Alfonso, Collins, Ronan, Dineen, Robert A, Duley, Lelia, Egea-Guerrero, Juan José, England, Timothy J, Karlinski, Michal, Krishnan, Kailash, Laska, Ann Charlotte, Law, Zhe Kang, Ovesen, Christian, Ozturk, Serefnur, Pocock, Stuart J, Roberts, Ian, Robinson, Thompson G, Roffe, Christine, Peters, Nils, Scutt, Polly, Thanabalan, Jegan, Werring, David, Whynes, David, Woodhouse, Lisa, Bath, Philip M

“…Tranexamic acid reduces death due to bleeding after trauma and postpartum haemorrhage. The aim of the study was to assess if tranexamic acid is safe, reduces…”
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Mechanical thrombectomy: can it be safely delivered out of hours in the UK? by Weddell, Jake, Parr, Emma, Knight, Stacey, Muddegowda, Girish, Natarajan, Indira, Chembala, Jayan, Ferdinand, Phillip, Ahmad, Nasar, Pencz, Zoltan, Rana, Saad, Warusevitane, Anushka, Jadun, Changez, Nayak, Sanjeev, Hashim, Zafar, Augustine, Albin, Sim, Julius, Roffe, Christine

“…Mechanical thrombectomy was approved by NICE as a treatment for stroke in 2016. However, most of the evidence is from studies conducted during working hours…”
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Mechanical thrombectomy for ischaemic stroke: the first UK case series by Ahmad, Nasar, Nayak, Sanjeev, Jadun, Changez, Natarajan, Indira, Jain, Palbha, Roffe, Christine

“…Endovascular treatments have the potential to accelerate reperfusion in acute ischaemic stroke with large vessel occlusion. In the UK only a few stroke centres…”
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Outcomes in Antiplatelet-Associated Intracerebral Hemorrhage in the TICH-2 Randomized Controlled Trial by Law, Zhe Kang, Desborough, Michael, Roberts, Ian, Al-Shahi Salman, Rustam, England, Timothy J, Werring, David J, Robinson, Thompson, Krishnan, Kailash, Dineen, Robert, Laska, Ann Charlotte, Peters, Nils, Egea-Guerrero, Juan Jose, Karlinski, Michal, Christensen, Hanne, Roffe, Christine, Bereczki, Daniel, Ozturk, Serefnur, Thanabalan, Jegan, Collins, Rónán, Beridze, Maia, Bath, Philip M, Sprigg, Nikola

“…Background Antiplatelet therapy increases the risk of hematoma expansion in intracerebral hemorrhage (ICH) while the effect on functional outcome is uncertain…”
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The SOS pilot study: a RCT of routine oxygen supplementation early after acute stroke--effect on recovery of neurological function at one week by Roffe, Christine, Ali, Khalid, Warusevitane, Anushka, Sills, Sheila, Pountain, Sarah, Allen, Martin, Hodsoll, John, Lally, Frank, Jones, Peter, Crome, Peter

“…Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous…”
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World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention by Grunwald, Iris Q, Mathias, Klaus, Bertog, Stefan, Snyder, Kenneth V, Sievert, Horst, Siddiqui, Adnan, Musialek, Piotr, Hornung, Marius, Papanagiotou, Panagiotes, Comelli, Simone, Pillai, Sanjay, Routledge, Helen, Nizankowski, Rafal T, Ewart, Ian, Fassbender, Klaus, Kühn, Anna L, Alvarez, Carlos A, Alekyan, Bagrat, Skrypnik, Dimitry, Politi, Maria, Tekieli, Lukasz, Haldis, Thomas, Gaikwad, Shailesh, Houston, John Graeme, Donald-Simspon, Helen, Guyler, Paul, Petrov, Ivo, Roffe, Christine, Abelson, Mark, Hargroves, David, Mani, Sunithi, Podlasek, Anna, Witkowski, Adam, Sievert, Kolja, Pawlowski, Krzysztof, Dziadkiewicz, Artur, Hopkins, Nelson L

“…Today, endovascular treatment (EVT) is the therapy of choice for strokes due to acute large vessel occlusion, irrespective of prior thrombolysis. This…”
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Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial by Tunnage, Bronwyn, Woodhouse, Lisa J, Dixon, Mark, Anderson, Craig, Ankolekar, Sandeep, Appleton, Jason, Cala, Lesley, England, Timothy, Krishnan, Kailash, Havard, Diane, Mair, Grant, Muir, Keith, Phillips, Steve, Potter, John, Price, Christopher, Randall, Marc, Robinson, Thompson G, Roffe, Christine, Sandset, Else, Siriwardena, Niro, Scutt, Polly, Wardlaw, Joanna M, Sprigg, Nikola, Bath, Philip M

“…Prehospital stroke trials will inevitably recruit patients with non-stroke conditions, so called stroke mimics. We undertook a pre-specified analysis to…”
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