Search Results - "ROESSLER, E"

Recent NMR investigations on molecular dynamics of polymer melts in bulk and in confinement by Rössler, E.A., Stapf, S., Fatkullin, N.

“…Polymer dynamics in the melt state cover a wide range in time and frequency, for both molecular weights below and above the entanglement length. Nuclear…”
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A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication by Arcos-Burgos, M, Jain, M, Acosta, M T, Shively, S, Stanescu, H, Wallis, D, Domené, S, Vélez, J I, Karkera, J D, Balog, J, Berg, K, Kleta, R, Gahl, W A, Roessler, E, Long, R, Lie, J, Pineda, D, Londoño, A C, Palacio, J D, Arbelaez, A, Lopera, F, Elia, J, Hakonarson, H, Johansson, S, Knappskog, P M, Haavik, J, Ribases, M, Cormand, B, Bayes, M, Casas, M, Ramos-Quiroga, J A, Hervas, A, Maher, B S, Faraone, S V, Seitz, C, Freitag, C M, Palmason, H, Meyer, J, Romanos, M, Walitza, S, Hemminger, U, Warnke, A, Romanos, J, Renner, T, Jacob, C, Lesch, K-P, Swanson, J, Vortmeyer, A, Bailey-Wilson, J E, Castellanos, F X, Muenke, M

“…Attention-Deficit/Hyperactivity Disorder (ADHD) has a very high heritability (0.8), suggesting that about 80% of phenotypic variance is due to genetic factors…”
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A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD by Jain, M, Vélez, J I, Acosta, M T, Palacio, L G, Balog, J, Roessler, E, Pineda, D, Londoño, A C, Palacio, J D, Arbelaez, A, Lopera, F, Elia, J, Hakonarson, H, Seitz, C, Freitag, C M, Palmason, H, Meyer, J, Romanos, M, Walitza, S, Hemminger, U, Warnke, A, Romanos, J, Renner, T, Jacob, C, Lesch, K-P, Swanson, J, Castellanos, F X, Bailey-Wilson, J E, Arcos-Burgos, M, Muenke, M

“…In previous studies of a genetic isolate, we identified significant linkage of attention deficit hyperactivity disorder (ADHD) to 4q, 5q, 8q, 11q and 17p. The…”
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How a Hedgehog might see holoprosencephaly by Roessler, Erich, Muenke, Maximilian

“…Detailed knowledge of the Hedgehog signaling pathway is fundamental to an understanding of vertebrate development as well as several birth defects in humans…”
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Loss-of-Function Mutations in Growth Differentiation Factor-1 ( GDF1) Are Associated with Congenital Heart Defects in Humans by Karkera, J.D., Lee, J.S., Roessler, E., Banerjee-Basu, S., Ouspenskaia, M.V., Mez, J., Goldmuntz, E., Bowers, P., Towbin, J., Belmont, J.W., Baxevanis, A.D., Schier, A.F., Muenke, M.

“…Congenital heart defects (CHDs) are among the most common birth defects in humans (incidence 8–10 per 1,000 live births). Although their etiology is often…”
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Cardioprotection via the skin: nociceptor-induced conditioning against cardiac MI in the NIC of time by Ren, Xiaoping, Roessler, Anne E, Lynch, 4th, Thomas L, Haar, Lauren, Mallick, Faryal, Lui, Yong, Tranter, Michael, Ren, Michelle Huan, Xie, Wen Rui, Fan, Guo-Chang, Zhang, Jun-Ming, Kranias, Evangelia G, Anjak, Ahmad, Koch, Sheryl, Jiang, Min, Miao, Qing, Wang, Yang, Cohen, Albert, Rubinstein, Jack, Weintraub, Neal L, Jones, W Keith

“…Timely reperfusion is still the most effective approach to limit infarct size in humans. Yet, despite advances in care and reduction in door-to-balloon times,…”
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Holoprosencephaly: A paradigm for the complex genetics of brain development by Roessler, E., Muenke, M.

“…Holoprosencephaly (HPE) is the most common major developmental defect of the forebrain in humans. Clinical expression is variable, ranging from a small brain…”
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Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function by Lacbawan, F, Solomon, B D, Roessler, E, El-Jaick, K, Domené, S, Vélez, J I, Zhou, N, Hadley, D, Balog, J Z, Long, R, Fryer, A, Smith, W, Omar, S, McLean, S D, Clarkson, K, Lichty, A, Clegg, N J, Delgado, M R, Levey, E, Stashinko, E, Potocki, L, Vanallen, M I, Clayton-Smith, J, Donnai, D, Bianchi, D W, Juliusson, P B, Njølstad, P R, Brunner, H G, Carey, J C, Hehr, U, Müsebeck, J, Wieacker, P F, Postra, A, Hennekam, R C M, van den Boogaard, M-J H, van Haeringen, A, Paulussen, A, Herbergs, J, Schrander-Stumpel, C T R M, Janecke, A R, Chitayat, D, Hahn, J, McDonald-McGinn, D M, Zackai, E H, Dobyns, W B, Muenke, M

“…Holoprosencephaly (HPE) is the most common structural malformation of the human forebrain. There are several important HPE mutational target genes, including…”
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Hexacoordinate Ru-based olefin metathesis catalysts with pH-responsive N-heterocyclic carbene (NHC) and N-donor ligands for ROMP reactions in non-aqueous, aqueous and emulsion conditions by Balof, Shawna L, Nix, K Owen, Olliff, Matthew S, Roessler, Sarah E, Saha, Arpita, Müller, Kevin B, Behrens, Ulrich, Valente, Edward J, Schanz, Hans-Jörg

“…Three new ruthenium alkylidene complexes (PCy3)Cl2(H2ITap)Ru=CHSPh (9), (DMAP)2Cl2(H2ITap)Ru=CHPh (11) and (DMAP)2Cl2(H2ITap)Ru=CHSPh (12) have been…”
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A Hypomorphic Allele in the FGF8 Gene Contributes to Holoprosencephaly and Is Allelic to Gonadotropin-Releasing Hormone Deficiency in Humans by Arauz, R.F., Solomon, B.D., Pineda-Alvarez, D.E., Gropman, A.L., Parsons, J.A., Roessler, E., Muenke, M.

“…Holoprosencephaly (HPE), the most common malformation of the human forebrain, may arise due to interacting genetic and environmental factors. To date, at least…”
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The Mutational Spectrum of the Sonic Hedgehog Gene in Holoprosencephaly: SHH Mutations Cause a Significant Proportion of Autosomal Dominant Holoprosencephaly by Nanni, Luisa, Ming, Jeffrey E., Bocian, Maureen, Steinhaus, Kathryn, Bianchi, Diana W., de Die-Smulders, Christine, Giannotti, Aldo, Imaizumi, Kiyoshi, Jones, Kenneth L., Del Campo, Miguel, Martin, Rick A., Meinecke, Peter, Pierpont, Mary Ella M., Robin, Nathaniel H., Young, Ian D., Roessler, Erich, Muenke, Maximilian

“…Holoprosencephaly (HPE) is a common developmental anomaly of the human forebrain and midface where the cerebral hemispheres fail to separate into distinct left…”
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Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly by Belloni, E, Muenke, M, Roessler, E, Traverse, G, Siegel-Bartelt, J, Frumkin, A, Mitchell, H.F, Donis-Keller, H, Helms, C, Hing, A.V, Heng, H.H.Q, Koop, B, Martindale, D, Rommens, J.M, Tsui, L.-C, Scherer, S.W

“…Holoprosencephaly (HPE) is a genetically and phenotypically heterogenous disorder involving the development of forebrain and midface, with an incidence of…”
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Mutations in the C-Terminal Domain of Sonic Hedgehog Cause Holoprosencephaly by Roessler, Erich, Belloni, Elena, Gaudenz, Karin, Vargas, Fernando, Scherer, Stephen W., Tsui, Lap-Chee, Muenke, Maximilian

“…Holoprosencephaly (HPE) is the most common brain anomaly in humans, involving abnormal formation and septation of the developing central nervous system. Among…”
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A Potent Inhibitor of Aminopeptidase P2 Reduces Reperfusion Injury in Models of Myocardial Infarction and Stroke by Lenz, Morgan R, Tsai, Shih-Yen, Roessler, Anne E, Wang, Yang, Sethupathi, Periannan, Jones, W Keith, Kartje, Gwendolyn L, Simmons, William H

“…During a myocardial infarction or ischemic stroke, blood flow to the heart or brain is partially blocked. This results in reduced delivery of oxygen and…”
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Social enrichment on the job: Complex work with people improves episodic memory, promotes brain reserve, and reduces the risk of dementia by Coleman, Max E., Roessler, Meghan E. H., Peng, Siyun, Roth, Adam R., Risacher, Shannon L., Saykin, Andrew J., Apostolova, Liana G., Perry, Brea L.

“…Individuals with more complex jobs experience better cognitive function in old age and a lower risk of dementia, yet complexity has multiple dimensions…”
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The Interleukin (IL) 2 Receptor β Chain is Shared by IL-2 and a Cytokine, Provisionally Designated IL-T, That Stimulates T-Cell Proliferation and the Induction of Lymphokine-Activated Killer Cells by Bamford, Richard N., Grant, Angus J., Burton, Jack D., Peters, Christian, Kurys, Gloria, Goldman, Carolyn K., Brennan, Jennifer, Roessler, Erich, Waldman, Thomas A.

“…Late-phase human T-cell lymphotropic virus I-associated adult T-cell leukemia cells express IL-2 receptors (IL-2R) but no longer produce IL-2. We have reported…”
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Exome Sequencing and High-Density Microarray Testing in Monozygotic Twin Pairs Discordant for Features of VACTERL Association by Solomon, B.D., Pineda-Alvarez, D.E., Hadley, D.W., Hansen, N.F., Kamat, A., Donovan, F.X., Chandrasekharappa, S.C., Hong, S.-K., Roessler, E., Mullikin, J.C.

“…Exome sequencing offers an efficient and affordable method to interrogate genetic factors involved in human disease. Performing exome sequencing of monozygotic…”
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Everolimus Versus Azathioprine in a Cyclosporine and Ketoconazole–Based Immunosuppressive Therapy in Kidney Transplant: 3-Year Follow-up of an Open-Label, Prospective, Cohort, Comparative Clinical Trial by Gonzalez, F, Espinoza, M, Herrera, P, Rocca, X, Reynolds, E, Lorca, E, Roessler, E, Hidalgo, J, Espinoza, O

“…Abstract In cyclosporine-based protocols, everolimus is more effective than azathioprine to reduce acute rejection. Ketoconazole may reduce cyclosporine and…”
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A Lymphokine, Provisionally Designated Interleukin T and Produced by a Human Adult T-Cell Leukemia Line, Stimulates T-Cell Proliferation and the Induction of Lymphokine-Activated Killer Cells by Burton, Jack D., Bamford, Richard N., Peters, Christian, Grant, Angus J., Kurys, Gloria, Goldman, Carolyn K., Brennan, Jennifer, Roessler, Erich, Waldmann, Thomas A.

“…In early phases of human T-cell lymphotropic virus I-induced adult T-cell leukemia (ATL), the malignant cell proliferation is associated with an autocrine…”
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Effectiveness and Cost of Replacing a Calcineurin Inhibitor With Sirolimus to Slow the Course of Chronic Kidney Disease in Renal Allografts by González, F, Espinoza, M, Reynolds, E, Herrera, P, Espinoza, O, Rocca, X, Lorca, E, Hidalgo, J, Roessler, E

“…Abstract Renal grafts suffer a progressive decrease in glomerular filtration rate (GFR) because of several factors including calcineurin inhibitor (CNI)…”
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