Search Results - "RODRIGUEZ, Noris"

2-Aryl-quinazolin-4(3H)-ones as an inhibitor of leishmania folate pathway: In vitro biological evaluation, mechanism studies and molecular docking by Romero, Angel H., Rodríguez, Noris, Oviedo, Henry

“…[Display omitted] •2-Arylquinazolin(3H)ones 2h and 2u showed from sub-micromolar response against resistant amastigote strains of L. braziliensis.•Compounds 2h…”
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Synthesis and Antitrypanosomal and Mechanistic Studies of a Series of 2‑Arylquinazolin-4-hydrazines: A Hydrazine Moiety as a Selective, Safe, and Specific Pharmacophore to Design Antitrypanosomal Agents Targeting NO Release by Romero, Angel H., Aguilera, Elena, Gotopo, Lourdes, Charris, Jaime, Rodríguez, Noris, Oviedo, Henry, Dávila, Belén, Cabrera, Gustavo, Cerecetto, Hugo

“…Nitric oxide (NO) represents a valuable target to design antitrypanosomal agents by its high toxicity against trypanosomatids and minimal side effects on host…”
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Identification of dehydroxy isoquine and isotebuquine as promising antileishmanial agents by Romero, Angel H., Rodríguez, Noris, López, Simón E., Oviedo, Henry

“…Traditional antimalarial drugs based on 4‐aminoquinolines have exhibited good antiproliferative activities against Leishmania parasites; however, their…”
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Antileismanial activity, mechanism of action study and molecular docking of 1,4‐bis(substituted benzalhydrazino)phthalazines by Romero, Angel H., Rodríguez, Noris, Oviedo, Henry, Lopez, Simón E.

“…To identify new agents for the treatment of American cutaneous leishmaniasis, a series of eight 1,4‐bis(substituted benzalhydrazino)phthalazines was evaluated…”
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Leishmanicidal Activity of Betulin Derivatives in Leishmania amazonensis; Effect on Plasma and Mitochondrial Membrane Potential, and Macrophage Nitric Oxide and Superoxide Production by Alcazar, Wilmer, Alakurtti, Sami, Padrón-Nieves, Maritza, Tuononen, Maija Liisa, Rodríguez, Noris, Yli-Kauhaluoma, Jari, Ponte-Sucre, Alicia

“…Herein, we evaluated in vitro the anti-leishmanial activity of betulin derivatives in Venezuelan isolates of , isolated from patients with therapeutic failure…”
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Antileishmanial activity, structure–activity relationship of series of 2‐(trifluoromethyl)benzo[b][1,8]naphthyridin‐4(1H)‐ones by Romero, Angel H., López, Simon E., Rodríguez, Noris, Oviedo, Henry

“…Trifluoromethyl‐substituted quinolones and their analogues have emerged as an interesting platform in the last 6 years to design antiparasite agents. Many of…”
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Synthesis and leishmanicidal evaluation of sulfanyl‐ and sulfonyl‐tethered functionalized benzoate derivatives featuring a nitroimidazole moiety by Rodríguez, Miguel, Gutiérrez, Joyce, Domínguez, José, Peixoto, Philippe A., Fernández, Alexis, Rodríguez, Noris, Deffieux, Denis, Rojas, Luis, Quideau, Stéphane, Pouységu, Laurent, Charris, Jaime

“…A series of new nitroimidazole‐containing derivatives was synthesized by coupling of 2‐[2‐(2‐methyl‐5‐nitro‐1H‐imidazol‐1‐yl)ethylthio]ethanol with diversely…”
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Amiodarone Destabilizes Intracellular Ca2+ Homeostasis and Biosynthesis of Sterols in Leishmania mexicana by SERRANO-MARTIN, Xenon, GARCIA-MARCHAN, Yael, FERNANDEZ, Alexis, RODRIGUEZ, Noris, ROJAS, Hector, VISBAL, Gonzalo, BENAIM, Gustavo

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Isolation and molecular identification of Leishmania chagasi from a bat (Carollia perspicillata) in northeastern Venezuela by De Lima, Hector, Rodríguez, Noris, Barrios, Miguel A, Ávila, Ángela, Cañizales, Israel, Gutiérrez, Saúl

“…This report describes the isolation of a Leishmania chagasi strain from a bat (Carollia perspicillata), and its identification using biological methods and…”
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The epidemiology and control of leishmaniasis in Andean countries by Davies, C R, Reithinger, R, Campbell-Lendrum, D, Feliciangeli, D, Borges, R, Rodriguez, N

“…This paper reviews the current knowledge of leishmaniasis epidemiology in Venezuela, Colombia, Ecuador, Peru, and Bolivia. In all 5 countries leishmaniasis is…”
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In vitro evaluation and in vivo efficacy of nitroimidazole-sulfanyl ethyl derivatives against Leishmania (V.) braziliensis and Leishmania (L.) mexicana by Blanco, Zuleima, Mijares, Michael R., Ramírez, Hegira, Fernandez-Moreira, Esteban, Oviedo, Henry J., Rodríguez, Noris M., Charris, Jaime E.

“…The aim of this study was to synthesize several small molecules of the type 5-nitroimidazole-sulfanyl and evaluate biological properties against the main…”
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Prevalence of contact dermatitis to glucose sensors in pediatric population and the main allergens involved by Vidal‐Albareda, Carmen, Yelmo‐Valverde, Rosa, Solórzano‐Zepeda, Cristiana, Rodríguez‐Muñoz, Noris, de‐la‐Hoz‐Caballer, Belén, González‐de‐Olano, David

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Cotton Rats ( Sigmodon hispidus ) and Black Rats ( Rattus rattus ) as Possible Reservoirs of Leishmania spp. in Lara State, Venezuela by De Lima, Hector, De Guglielmo, Zoraya, Rodríguez, Armando, Convit, Jacinto, Rodriguez, Noris

“…A total of 519 wild animals belonging to eleven species were collected during a two year study in a cutaneous leishmaniasis endemic area in Venezuela (La…”
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Canine visceral leishmaniasis on Margarita Island (Nueva Esparta, Venezuela) by Zerpa, Olga, Ulrich, Marian, Negrón, Emilia, Rodríguez, Noris, Centeno, Marta, Rodríguez, Vestalia, Barrios, Rosa M., Belizario, Doris, Reed, Steven, Convit, Jacinto

“…The frequency of American visceral leishmaniasis affecting humans on Margarita Island, Venezuela, has increased in recent years, and infected dogs appear to…”
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Overexpression of the Leishmania amazonensis Ca2+‐ATPase gene lmaa1 enhances virulence by Rodriguez, Noris M., Docampo, Roberto, Lu, Hong‐gang, Scott, David A.

“…Summary A gene for a Ca2+‐transporting ATPase (lmaa1) from the trypanosomatid parasite Leishmania (mexicana) amazonensis was overexpressed in two clones of L…”
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Eficacia de un ácido kaurénico extraído de la planta venezolana Wedelia trilobata (Asterácea) contra Leishmania (Viannia) braziliensis by Brito, Solanny, Crescente, Oscar, Fernández, Alexis, Coronado, Aura, Rodriguez, Noris

“…Introducción. La leishmaniasis es un grave problema de salud pública y aun no existe un tratamiento eficaz para la enfermedad. Por esta razón, es necesario…”
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Visceral Leishmaniasis Due to a Leishmania Variant That Shares Kinetoplast DNA Sequences with Leishmania braziliensis and Leishmania mexicana in a Patient Infected with Human Immunodeficiency Virus: Identification of the Leishmania Species with Use of the Polymerase Chain Reaction by Hernández, Dimas E., Rodriguez, Noris, Wessolossky, Mireya, Convit, Jacinto

“…We describe a female patient who was infected with human immunodeficiency virus (HIV) and who developed visceral leishmaniasis due to a variant of Leishmania…”
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Therapy of Venezuelan Patients with Severe Mucocutaneous or Early Lesions of Diffuse Cutaneous Leishmaniasis with a Vaccine Containing Pasteurized Leishmania Promastigotes and Bacillus Calmette-Guerin - Preliminary Report by Convit, Jacinto, Ulrich, Marian, Polegre, María Argelia, Avila, Angela, Rodríguez, Noris, Mazzedo, Maria Ilina, Blanco, Belkis

“…Severe mucocutaneous (MCL) and diffuse (DCL) forms of American cutaneous leishmaniasis (ACL) are infrequent in Venezuela. Chemotherapy produces only transitory…”
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Correlation between glucose uptake and membrane potential in Leishmania parasites isolated from DCL patients with therapeutic failure: a proof of concept by Padrón-Nieves, Maritza, Machuca, Claudia, Díaz, Emilia, Cotrim, Paulo, Rodriguez, Noris, Ponte-Sucre, Alicia

“…Besides infection with drug-resistant parasites, therapeutic failure in leishmaniasis may be caused by altered drug pharmacokinetics, re-infection, and host…”
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Isolation of Leishmania (Viannia) braziliensis from Lutzomyia spinicrassa (species group Verrucarum) Morales Osorno Mesa, Osorno & Hoyos 1969, in the Venezuelan Andean Region by Perruolo, G., Noris Rodríguez, N., Feliciangeli, M.D.

“…Natural infection with Leishmania spp. in phlebotomine sandflies was searched for during a longitudinal study carried out from July 1997 to July 1998 in the…”
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