Search Results - "RODRIGUES, A. A."
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Silicon's Role in Abiotic and Biotic Plant Stresses
Published in Annual review of phytopathology (04-08-2017)“…Silicon (Si) plays a pivotal role in the nutritional status of a wide variety of monocot and dicot plant species and helps them, whether directly or…”
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Drug Interactions Involving 17α‐Ethinylestradiol: Considerations Beyond Cytochrome P450 3A Induction and Inhibition
Published in Clinical pharmacology and therapeutics (01-06-2022)“…It is widely acknowledged that drug‐drug interactions (DDIs) involving estrogen (17α‐ethinylestradiol (EE))‐containing oral contraceptives (OCs) are important…”
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Reimagining the Framework Supporting the Static Analysis of Transporter Drug Interaction Risk; Integrated Use of Biomarkers to Generate Pan‐Transporter Inhibition Signatures
Published in Clinical pharmacology and therapeutics (01-05-2023)“…Solute carrier (SLC) transporters present as the loci of important drug–drug interactions (DDIs). Therefore, sponsors generate in vitro half‐maximal inhibitory…”
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Photodynamic therapy review: principles, photosensitizers, applications, and future directions
Published in Pharmaceutics (25-08-2021)“…"This article belongs to the Special Issue: Special Issue in Honor of Dr. Michael Weber’s 70th Birthday: Photodynamic Therapy: Rising Star in Pharmaceutical…”
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5
Contribution of structural lightweight aggregate concrete to the reduction of thermal bridging effect in buildings
Published in Construction & building materials (15-09-2016)“…•The energy performance of SLWAC in residential buildings was studied.•SLWAC proved to be able to significantly improve the thermal bridging effect.•SLWAC can…”
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6
Evolution and function of genomic imprinting in plants
Published in Genes & development (15-12-2015)“…Genomic imprinting, an inherently epigenetic phenomenon defined by parent of origin-dependent gene expression, is observed in mammals and flowering plants…”
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Mass spectrometry-based plant metabolomics: Metabolite responses to abiotic stress
Published in Mass spectrometry reviews (01-09-2016)“…Metabolomics is one omics approach that can be used to acquire comprehensive information on the composition of a metabolite pool to provide a functional screen…”
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Endogenous Probes for Drug Transporters: Balancing Vision With Reality
Published in Clinical pharmacology and therapeutics (01-03-2018)“…Various endogenous probes have been identified for a number of hepatic and renal drug transporters and available clinical data indicate that they could be…”
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Thermal, luminous and energy performance of solar control films in single-glazed windows: Use of energy performance criteria to support decision making
Published in Energy and buildings (01-09-2019)“…•Thermal, luminous and energy efficiency of single-glass with solar films is assessed.•Experimental data was used to calibrate a simulation model in EnergyPlus…”
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10
Clustering algorithms: A comparative approach
Published in PloS one (15-01-2019)“…Many real-world systems can be studied in terms of pattern recognition tasks, so that proper use (and understanding) of machine learning methods in practical…”
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Assessment of the visual, thermal and energy performance of static vs thermochromic double-glazing under different European climates
Published in Building and environment (01-06-2022)“…Highly glazed buildings are typically responsible for significant solar heat gains/losses and, consequently, considerable cooling and heating energy needs…”
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Profiling of Drug-Metabolizing Enzymes and Transporters in Human Tissue Biopsy Samples: A Review of the Literature
Published in The Journal of pharmacology and experimental therapeutics (01-03-2020)“…Within the drug pharmacokinetics (PK)-absorption, distribution, metabolism, and excretion (ADME) research community, investigators regularly generate in vitro…”
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Organic Anion Transporter 2: An Enigmatic Human Solute Carrier
Published in Drug metabolism and disposition (01-02-2017)“…As a member of the solute carrier 22A (SLC22A) family, organic anion transporter 2 (OAT2; SLC22A7) is emerging as an important drug transporter because of its…”
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Biomarker‐Informed Model‐Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug‐Drug Interactions
Published in Clinical pharmacology and therapeutics (01-02-2022)“…Quantitative prediction of drug‐drug interactions (DDIs) involving organic anion transporting polypeptide (OATP)1B1/1B3 inhibition is limited by uncertainty in…”
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Species differences in bile acids I. Plasma and urine bile acid composition
Published in Journal of applied toxicology (01-10-2018)“…Maintenance of bile acid (BA) homeostasis is essential to achieve their physiologic functions and avoid their toxic effects. The marked differences in BA…”
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The use of 3D GIS to analyse the influence of urban context on buildings’ solar energy potential
Published in Energy and buildings (15-10-2018)“…•The impact of the urban context on buildings' solar energy potential was assessed.•3D GIS was used to build a city block in Lisbon and surrounding urban…”
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Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals – A comprehensive review
Published in Advanced drug delivery reviews (01-06-2018)“…Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of inadequate drug dissolution rates, is one of the most significant…”
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Global Biodiversity Conservation Priorities
Published in Science (American Association for the Advancement of Science) (07-07-2006)“…The location of and threats to biodiversity are distributed unevenly, so prioritization is essential to minimize biodiversity loss. To address this need,…”
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Cynomolgus Monkey as an Emerging Animal Model to Study Drug Transporters: In Vitro, In Vivo, In Vitro-to-In Vivo Translation
Published in Drug metabolism and disposition (01-03-2022)“…Membrane transporters have been recognized as one of the key determinants of pharmacokinetics and are also known to affect the efficacy and toxicity of drugs…”
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Crime prediction through urban metrics and statistical learning
Published in Physica A (01-09-2018)“…Understanding the causes of crime is a longstanding issue in researcher’s agenda. While it is a hard task to extract causality from data, several linear models…”
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