Search Results - "ROCKWOOD, Alan L"
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Liquid chromatography-tandem mass spectrometry applications in endocrinology
Published in Mass spectrometry reviews (01-05-2010)“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been recognized as a primary methodology for the accurate analysis of endogenous steroid hormones…”
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Liquid chromatography tandem mass spectrometry for analysis of steroids in clinical laboratories
Published in Clinical biochemistry (2011)“…Liquid chromatography tandem mass spectrometry is one of the most specific techniques available in clinical laboratories. In the past, immunoassays were the…”
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LC-MS/MS Measurement of Parathyroid Hormone-Related Peptide
Published in Clinical chemistry (Baltimore, Md.) (01-01-2016)“…Parathyroid hormone-related peptide (PTHrP) is involved in activating pathways, allowing tumor cells to form bone metastases. Measurement of PTHrP is used for…”
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State-of-the-Art of Serum Testosterone Measurement by Isotope Dilution-Liquid Chromatography- Tandem Mass Spectrometry
Published in Clinical chemistry (Baltimore, Md.) (01-08-2008)“…The recent interest of clinical laboratories in developing serum testosterone assays based on isotope dilution-liquid chromatography-tandem mass spectrometry…”
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Harmonization of Liquid Chromatography–Tandem Mass Spectrometry Protein Assays
Published in Clinics in laboratory medicine (01-09-2018)“…Harmonization of diagnostic test results is fundamental to the effective use of laboratory testing in the diagnosis, treatment, and monitoring of disease…”
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Mid-pregnancy, perinatal, and neonatal reproductive endocrinology: a prospective cohort study in twins and singleton control subjects
Published in Fertility and sterility (01-12-2015)“…Objective To answer the questions: Are perinatal reproductive hormone profiles different in case of a twin compared with a singleton pregnancy? Are…”
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Free Thyroid Hormones in Serum by Direct Equilibrium Dialysis and Online Solid-Phase Extraction-Liquid Chromatography/Tandem Mass Spectrometry
Published in Clinical chemistry (Baltimore, Md.) (01-04-2008)“…Measurements of free thyroxine (FT4) and free triiodothyronine (FT3) are important for the diagnosis and monitoring of thyroid diseases. Considerable…”
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Direct measurement of free estradiol in human serum by equilibrium dialysis–liquid chromatography–tandem mass spectrometry and reference intervals of free estradiol in women
Published in Clinica chimica acta (14-06-2012)“…Measurement of free estradiol offers a better representation of the bioactive fraction of the hormone. We describe a direct equilibrium dialysis–liquid…”
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Efficient Calculation of Accurate Masses of Isotopic Peaks
Published in Journal of the American Society for Mass Spectrometry (01-03-2006)“…This paper presents a new method for calculating accurate masses of isotopic peaks. It is based on breaking the calculation into a binary series of…”
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ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides
Published in The Journal of immunology (1950) (15-08-2013)“…Effective CD8(+) T cell responses depend on presentation of a stable peptide repertoire by MHC class I (MHC I) molecules on the cell surface. The overall…”
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Relationship between Serum Testosterone and Fracture Risk in Men: A Comparison of RIA and LC-MS/MS
Published in Clinical chemistry (Baltimore, Md.) (01-09-2015)“…Serum testosterone can be measured by LC-MS/MS and RIA. We investigated whether the testosterone-fracture relationship was affected by the method of…”
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Development and Performance Evaluation of a Tandem Mass Spectrometry Assay for 4 Adrenal Steroids
Published in Clinical chemistry (Baltimore, Md.) (01-08-2006)“…Congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by a deficiency of 1 of 4 enzymes required for the synthesis of…”
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Steroid profiles in ovarian follicular fluid in women with and without polycystic ovary syndrome, analyzed by liquid chromatography-tandem mass spectrometry
Published in Fertility and sterility (01-11-2010)“…Objective To compare steroid concentrations and steroid product-to-precursor ratios in ovarian follicular fluid (FF) from women with polycystic ovary syndrome…”
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Performance Characteristics of a Novel Tandem Mass Spectrometry Assay For Serum Testosterone
Published in Clinical chemistry (Baltimore, Md.) (01-01-2006)“…Commercial immunoassays for testosterone (Te) may give inaccurate results for samples from women and children, leading to misdiagnosis and inappropriate…”
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Perceived stress at work is associated with lower levels of DHEA-S
Published in PloS one (2013)“…It is known that long-term psychosocial stress may cause or contribute to different diseases and symptoms and accelerate aging. One of the consequences of…”
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Meaning and Measurability of Single-Ion Activities, the Thermodynamic Foundations of pH, and the Gibbs Free Energy for the Transfer of Ions between Dissimilar Materials
Published in Chemphyschem (22-06-2015)“…Considering the relationship between concentration and vapor pressure (or the relationship between concentration and fugacity) single‐ion activity coefficients…”
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Large Scale Mass Spectrometric Profiling of Peptides Eluted from HLA Molecules Reveals N-Terminal-Extended Peptide Motifs
Published in The Journal of immunology (1950) (01-10-2008)“…The majority of >2000 HLA class I molecules can be clustered according to overlapping peptide binding specificities or motifs recognized by CD8(+) T cells. HLA…”
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Choline in Whole Blood and Plasma: Sample Preparation and Stability
Published in Clinical chemistry (Baltimore, Md.) (01-03-2008)“…Choline is critical for a variety of biological functions and has been investigated as a biomarker for various pathological conditions including acute coronary…”
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Quantitation of nicotine, its metabolites, and other related alkaloids in urine, serum, and plasma using LC-MS-MS
Published in Methods in molecular biology (Clifton, N.J.) (2010)“…We describe a method for the quantitative analysis of nicotine, cotinine, trans-3'-hydroxy cotinine, nornicotine, and anabasine in urine, serum, and plasma…”
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Cortisol and cortisone analysis in serum and plasma by atmospheric pressure photoionization tandem mass spectrometry
Published in Clinical biochemistry (01-05-2004)“…Objectives: Cortisol metabolism is controlled by 11β-hydroxysteroid dehydrogenase (11β-HSD) isoenzymes, which interconvert cortisol and cortisone. Accurate…”
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