Search Results - "ROCCO, Vincent P"

Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1 by Wainscott, David B, Little, Sheila P, Yin, Tinggui, Tu, Yuan, Rocco, Vincent P, He, John X, Nelson, David L

“…The hemagglutinin-tagged human trace amine-associated receptor1 (TAAR1) was stably coexpressed with rat Galpha(s) in the AV12-664 cell line, and receptor…”
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Advances toward new antidepressants beyond SSRIS: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 4 by ROCCO, Vincent P, SPINAZZE, Patrick G, TAKEUCHI, Kumiko, KOHN, Todd J, HONIGSCHMIDT, Nicholas A, NELSON, David L, WAINSCOTT, D. Bradley, AHMAD, Laura J, SHAW, Janice, THRELKELD, Penny G, WONG, David T

“…A series of 1-(1H-indol-4-yloxy)-3-(4-arylpiperidinyl)propan-2-ols possessing potent dual 5-HT(1A) receptor antagonism and serotonin reuptake inhibition was…”
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Advances toward new antidepressants beyond SSRIs : 1-Aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 5 by TAKEUCHI, Kumiko, KOHN, Todd J, LODGE, David, MARTIN, Laura J, SHAW, Janice, THRELKELD, Penny G, WONG, David T, HONIGSCHMIDT, Nicholas A, ROCCO, Vincent P, SPINAZZE, Patrick G, HEMRICK-LUECKE, Susan K, THOMPSON, Linda K, EVANS, David C, RASMUSSEN, Kurt, KOGER, Deanna

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT1A receptor antagonism and serotonin reuptake inhibition was discovered…”
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Advances toward new antidepressants beyond SSRIs: 1-Aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1 by TAKEUCHI, Kumiko, KOHN, Todd J, THRELKELD, Penny G, WONG, David T, HONIGSCHMIDT, Nicholas A, ROCCO, Vincent P, SPINAZZE, Patrick G, KOCH, Daniel J, NELSON, David L, WAINSCOTT, D. Bradley, AHMAD, Laura J, SHAW, Janice

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT(1A) receptor antagonism and serotonin reuptake inhibition was discovered…”
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Advances toward new antidepressants beyond SSRIS: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3 by TAKEUCHI, Kumiko, KOHN, Todd J, SHAW, Janice, THRELKELD, Penny G, WONG, David T, HONIGSCHMIDT, Nicholas A, ROCCO, Vincent P, SPINAZZE, Patrick G, ATKINSON, Steven T, HERTEL, Larry W, NELSON, David L, WAINSCOTT, D. Bradley, AHMAD, Laura J

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT(1A) receptor antagonism and serotonin reuptake inhibition was discovered…”
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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 2 by TAKEUCHI, Kumiko, KOHN, Todd J, AHMAD, Laura J, SHAW, Janice, THRELKELD, Penny G, WONG, David T, HONIGSCHMIDT, Nicholas A, ROCCO, Vincent P, SPINAZZE, Patrick G, KOCH, Daniel J, ATKINSON, Steven T, HERTEL, Larry W, NELSON, David L, WAINSCOTT, D. Bradley

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Intramolecular [2 + 2] photocycloaddition of 4-substituted cyclopent-2-en-1-ones by Dauben, William G, Rocco, Vincent P, Shapiro, Gideon

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Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase by McNulty, Ann M, Audia, James E, Bemis, Kerry G, Goode, Robin L, Rocco, Vincent P, Neubauer, Blake Lee

“…Type I and type II steroid 5α-reductases (5α-R) catalyze the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 is a benzoquinolinone (BQ)…”
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Greater effects of fluoxetine and its combination with (-)-pindolol in elevating hypothalamic serotonin in rats during dark hours by Dreshfield, L J, Rocco, V P, Wong, D T

“…Administration of fluoxetine (10 mg/kg i.p.) caused a significantly greater increase in extracellular 5-HT levels in hypothalamus of rats adapted to a reverse…”
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Advances toward new antidepressants beyond SSRIs: 1-Aryloxy-3-piperidinylpropan-2-ols with dual 5-HT 1A receptor antagonism/SSRI activities. Part 5 by Takeuchi, Kumiko, Kohn, Todd J., Honigschmidt, Nicholas A., Rocco, Vincent P., Spinazze, Patrick G., Hemrick-Luecke, Susan K., Thompson, Linda K., Evans, David C., Rasmussen, Kurt, Koger, Deanna, Lodge, David, Martin, Laura J., Shaw, Janice, Threlkeld, Penny G., Wong, David T.

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT 1A receptor antagonism and serotonin reuptake inhibition was discovered. 1-(1…”
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Advances toward new antidepressants beyond SSRIs: 1-Aryloxy-3-piperidinylpropan-2-ols with dual 5-HT sub(1A) receptor antagonism/SSRI activities by Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Hemrick-Luecke, Susan K, Thompson, Linda K, Evans, David C, Rasmussen, Kurt, Koger, Deanna, Lodge, David, Martin, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5- HT sub(1A) receptor antagonism and serotonin reuptake inhibition was discovered…”
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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT 1A receptor antagonism/SSRI activities. Part 4 by Rocco, Vincent P., Spinazze, Patrick G., Kohn, Todd J., Honigschmidt, Nicholas A., Nelson, David L., Bradley Wainscott, D., Ahmad, Laura J., Shaw, Janice, Threlkeld, Penny G., Wong, David T., Takeuchi, Kumiko

“…A series of 1-(1 H-indol-4-yloxy)-3-(4-arylpiperidinyl)propan-2-ols possessing potent dual 5-HT 1A receptor antagonism and serotonin reuptake inhibition was…”
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Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2 by Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Koch, Daniel J, Atkinson, Steven T, Hertel, Larry W, Nelson, David L, Wainscott, D Bradley, Ahmad, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

“…Potent 5-HT1A/SSRIs at low nanomolar and subnanomolar concentrations were identified in a series of…”
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Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT 1A receptor antagonism/SSRI activities. Part 2 by Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Koch, Daniel J, Atkinson, Steven T, Hertel, Larry W, Nelson, David L, Wainscott, D.Bradley, Ahmad, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

“…Potent 5-HT1A/SSRIs at low nanomolar and subnanomolar concentrations were identified in a series of 1-(1 H-indol-4-yloxy)-3-(4-benzo[…”
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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT 1A receptor antagonism/SSRI activities. Part 1 by Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Koch, Daniel J, Nelson, David L, Wainscott, D.Bradley, Ahmad, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT 1A receptor antagonism and serotonin reuptake inhibition was discovered. 1-(1…”
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Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT 1A receptor antagonism/SSRI activities. Part 3 by Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Atkinson, Steven T, Hertel, Larry W, Nelson, David L, Wainscott, D.Bradley, Ahmad, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

“…A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT 1A receptor antagonism and serotonin reuptake inhibition was discovered…”
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Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions by Smith, Edward C.R., McQuaid, Loretta A., Goode, Robin L., McNulty, Ann M., Neubauer, Blake Lee, Rocco, Vincent P., Audia, James E.

“…Benzoquinolinones have been shown to be potent, selective inhibitors of the Type I 5α-reductase enzyme, which is responsible for the production of…”
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