Search Results - "ROBINSON, ROBERT C."

The evolution of compositionally and functionally distinct actin filaments by Gunning, Peter W, Ghoshdastider, Umesh, Whitaker, Shane, Popp, David, Robinson, Robert C

“…The actin filament is astonishingly well conserved across a diverse set of eukaryotic species. It has essentially remained unchanged in the billion years that…”
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AlphaFold2: A versatile tool to predict the appearance of functional adaptations in evolution: Profilin interactions in uncultured Asgard archaea by Ponlachantra, Khongpon, Suginta, Wipa, Robinson, Robert C., Kitaoku, Yoshihito

“…Abstract The release of AlphaFold2 (AF2), a deep‐learning‐aided, open‐source protein structure prediction program, from DeepMind, opened a new era of molecular…”
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Gelsolin: The tail of a molecular gymnast by Nag, Shalini, Larsson, Mårten, Robinson, Robert C., Burtnick, Leslie D.

“…Gelsolin superfamily members are Ca2+‐dependent, multidomain regulators of the actin cytoskeleton. Calcium binding activates gelsolin by inducing molecular…”
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Proteomics profiling of arginine methylation defines PRMT5 substrate specificity by Musiani, Daniele, Bok, Jabez, Massignani, Enrico, Wu, Liling, Tabaglio, Tommaso, Ippolito, Marica Rosaria, Cuomo, Alessandro, Ozbek, Umut, Zorgati, Habiba, Ghoshdastider, Umesh, Robinson, Robert C, Guccione, Ernesto, Bonaldi, Tiziana

“…Protein arginine methyltransferases (PRMTs) catalyze arginine methylation on both chromatin-bound and cytoplasmic proteins. Accumulating evidence supports the…”
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Tree of motility – A proposed history of motility systems in the tree of life by Miyata, Makoto, Robinson, Robert C., Uyeda, Taro Q. P., Fukumori, Yoshihiro, Fukushima, Shun‐ichi, Haruta, Shin, Homma, Michio, Inaba, Kazuo, Ito, Masahiro, Kaito, Chikara, Kato, Kentaro, Kenri, Tsuyoshi, Kinosita, Yoshiaki, Kojima, Seiji, Minamino, Tohru, Mori, Hiroyuki, Nakamura, Shuichi, Nakane, Daisuke, Nakayama, Koji, Nishiyama, Masayoshi, Shibata, Satoshi, Shimabukuro, Katsuya, Tamakoshi, Masatada, Taoka, Azuma, Tashiro, Yosuke, Tulum, Isil, Wada, Hirofumi, Wakabayashi, Ken‐ichi

“…Motility often plays a decisive role in the survival of species. Five systems of motility have been studied in depth: those propelled by bacterial flagella,…”
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Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization by Xue, Bo, Leyrat, Cedric, Grimes, Jonathan M, Robinson, Robert C

“…Significance Thymosin-β4 (Tβ4) sequesters actin monomers to help maintain the high concentrations of unpolymerized actin in higher eukaryotic cells. Despite…”
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Direct and convenient measurement of plasmid stability in lab and clinical isolates of E. coli by Chen, Siyi, Larsson, Mårten, Robinson, Robert C., Chen, Swaine L.

“…Plasmids are important mobile elements in bacteria, contributing to evolution, virulence, and antibiotic resistance. Natural plasmids are generally large and…”
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Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein by Park, Hee-Won, Ma, Zhujun, Zhu, Haizhong, Jiang, Shimin, Robinson, Robert C., Endow, Sharyn A.

“…Kinesin microtubule motor proteins play essential roles in division, including attaching chromosomes to spindles and crosslinking microtubules for spindle…”
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Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis by Scipion, Clement P. M., Ghoshdastider, Umesh, Ferrer, Fernando J., Yuen, Tsz-Ying, Wongsantichon, Jantana, Robinson, Robert C.

“…The structure of the actin filament is known at a resolution that has allowed the architecture of protein components to be unambiguously assigned. However,…”
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Exploring the A22-Bacterial Actin MreB Interaction through Molecular Dynamics Simulations by Awuni, Yaw, Jiang, Shimin, Robinson, Robert C, Mu, Yuguang

“…MreB is an actin-like cytoskeleton protein that plays a vital role in the maintenance of the rod-shaped morphology of many bacteria. S-(3,4-Dichlorobenzyl)…”
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Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts by Shrestha, Man Mohan, Lim, Chun-Yan, Bi, Xuezhi, Robinson, Robert C, Han, Weiping

“…Insulin and muscle contractions mediate glucose transporter 4 (GLUT4) translocation and insertion into the plasma membrane (PM) for glucose uptake in skeletal…”
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The structure of the actin filament uncapping complex mediated by twinfilin by Mwangangi, Dennis M, Manser, Edward, Robinson, Robert C

“…Uncapping of actin filaments is essential for driving polymerization and depolymerization dynamics from capping protein-associated filaments; however, the…”
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ATP competes with PIP2 for binding to gelsolin by Szatmári, Dávid, Xue, Bo, Kannan, Balakrishnan, Burtnick, Leslie D, Bugyi, Beáta, Nyitrai, Miklós, Robinson, Robert C

“…Gelsolin is a severing and capping protein that targets filamentous actin and regulates filament lengths near plasma membranes, contributing to cell movement…”
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The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea by Tran, Linh T., Akıl, Caner, Senju, Yosuke, Robinson, Robert C.

“…Membrane-enclosed organelles are defining features of eukaryotes in distinguishing these organisms from prokaryotes. Specification of distinct membranes is…”
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Coherent diffractive imaging of microtubules using an X-ray laser by Brändén, Gisela, Hammarin, Greger, Harimoorthy, Rajiv, Johansson, Alexander, Arnlund, David, Malmerberg, Erik, Barty, Anton, Tångefjord, Stefan, Berntsen, Peter, DePonte, Daniel P., Seuring, Carolin, White, Thomas A., Stellato, Francesco, Bean, Richard, Beyerlein, Kenneth R., Chavas, Leonard M. G., Fleckenstein, Holger, Gati, Cornelius, Ghoshdastider, Umesh, Gumprecht, Lars, Oberthür, Dominik, Popp, David, Seibert, Marvin, Tilp, Thomas, Messerschmidt, Marc, Williams, Garth J., Loh, N. Duane, Chapman, Henry N., Zwart, Peter, Liang, Mengning, Boutet, Sébastien, Robinson, Robert C., Neutze, Richard

“…X-ray free electron lasers (XFELs) create new possibilities for structural studies of biological objects that extend beyond what is possible with synchrotron…”
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Functional display of bioactive peptides on the vGFP scaffold by Chee, Sharon Min Qi, Wongsantichon, Jantana, Yi, Lau Sze, Sana, Barindra, Frosi, Yuri, Robinson, Robert C., Ghadessy, Farid J.

“…Grafting bioactive peptides into recipient protein scaffolds can often increase their activities by conferring enhanced stability and cellular longevity. Here,…”
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Calcium-controlled conformational choreography in the N-terminal half of adseverin by Chumnarnsilpa, Sakesit, Robinson, Robert C., Grimes, Jonathan M., Leyrat, Cedric

“…Adseverin is a member of the calcium-regulated gelsolin superfamily of actin-binding proteins. Here we report the crystal structure of the calcium-free…”
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Directed Evolution of a Thermostable Quorum-quenching Lactonase from the Amidohydrolase Superfamily by Chow, Jeng Yeong, Xue, Bo, Lee, Kang Hao, Tung, Alvin, Wu, Long, Robinson, Robert C., Yew, Wen Shan

“…A thermostable quorum-quenching lactonase from Geobacillus kaustophilus HTA426 (GI: 56420041) was used as an initial template for in vitro directed evolution…”
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Structural characterization of a capping protein interaction motif defines a family of actin filament regulators by Kannan, Balakrishnan, Aguda, Adeleke H, Robinson, Robert C, Hernandez-Valladares, Maria, Kim, Taekyung, Tung, Alvin, Larsson, Mårten, Cooper, John A

“…Capping protein (CP) regulates actin dynamics through binding to the barbed ends of actin filaments. Structural analysis of the CP interaction motifs from…”
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Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling by Yang, Wulin, Thein, Shermaine, Lim, Chun-Yan, Ericksen, Russell E, Sugii, Shigeki, Xu, Feng, Robinson, Robert C, Kim, Jae Bum, Han, Weiping

“…Extensive actin cytoskeleton remodelling occurs during adipocyte development. We have previously shown that disruption of stress fibres by the actin-severing…”
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