Search Results - "ROBERTS, Lynne M."

Fluorescent Reporter Proteins for the Tonoplast and the Vacuolar Lumen Identify a Single Vacuolar Compartment in Arabidopsis Cells by Hunter, Paul R, Craddock, Christian P, Di Benedetto, Sara, Roberts, Lynne M, Frigerio, Lorenzo

“…We generated fusions between three Arabidopsis (Arabidopsis thaliana) tonoplast intrinsic proteins (TIPs; α-, γ-, and δ-TIP) and yellow fluorescent protein…”
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Preferences of Australian healthcare providers regarding education on long-term health after hypertensive disorders of pregnancy: a qualitative study by Roth, Heike, Morcos, Veronica, Roberts, Lynne M, Hanley, Lisa, Homer, Caroline S E, Henry, Amanda

“…Objectives)To explore Australian healthcare providers’ (HCPs’) preferred content, format and access to education regarding long-term health after hypertensive…”
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Assessing Australian women’s knowledge and knowledge preferences about long-term health after hypertensive disorders of pregnancy: a survey study by Roth, Heike, Homer, Caroline S E, LeMarquand, Grace, Roberts, Lynne M, Hanley, LIsa, Brown, Mark, Henry, Amanda

“…ObjectivesTo (1) assess women’s current knowledge regarding long-term cardiovascular health after hypertensive disorders of pregnancy (2) elicit women’s…”
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An Arabidopsis reticulon and the atlastin homologue RHD3-like2 act together in shaping the tubular endoplasmic reticulum by Lee, Hannah, Sparkes, Imogen, Gattolin, Stefano, Dzimitrowicz, Natasha, Roberts, Lynne M., Hawes, Chris, Frigerio, Lorenzo

“…The endoplasmic reticulum (ER) is a network of membrane sheets and tubules connected via three-way junctions. A family of proteins, the reticulons, are…”
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Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol by Susic, Daniella, Davis, Gregory, O' Sullivan, Anthony J, McGovern, Emily, Harris, Katie, Roberts, Lynne M, Craig, Maria E, Mangos, George, Hold, Georgina L, El-Omar, Emad M, Henry, Amanda

“…Pregnancy induces significant physiological and cardiometabolic changes, and is associated with alterations in the maternal microbiota. Increasing rates of…”
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Cytosolic entry of Shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p by Li, Shuyu, Spooner, Robert A, Hampton, Randolph Y, Lord, J Michael, Roberts, Lynne M

“…Escherichia coli Shiga-like toxin 1 normally traffics to the endoplasmic reticulum (ER) in sensitive mammalian cells from where the catalytic A chain (SLTxA1)…”
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Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum by Spooner, Robert A, Hart, Philip J, Cook, Jonathan P, Pietroni, Paola, Rogon, Christian, Höhfeld, Jörg, Roberts, Lynne M, Lord, J. Michael

“…The plant cytotoxin ricin enters target mammalian cells by receptor-mediated endocytosis and undergoes retrograde transport to the endoplasmic reticulum (ER)…”
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Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins by Amessou, Mohamed, Fradagrada, Alexandre, Falguières, Thomas, Lord, J. Michael, Smith, Daniel C, Roberts, Lynne M, Lamaze, Christophe, Johannes, Ludger

“…Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network…”
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Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum by Spooner, Robert A, Watson, Peter D, Marsden, Catherine J, Smith, Daniel C, Moore, Katherine A H, Cook, Jonathon P, Lord, J Michael, Roberts, Lynne M

“…Cells expressing ricin B chain within the secretory pathway are significantly more resistant to intoxication by ricin holotoxin but not to other cytotoxins…”
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Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum by Li, Shuyu, Spooner, Robert A, Allen, Stuart C H, Guise, Christopher P, Ladds, Graham, Schnöder, Tina, Schmitt, Manfred J, Lord, J Michael, Roberts, Lynne M

“…We report that a toxic polypeptide retaining the potential to refold upon dislocation from the endoplasmic reticulum (ER) to the cytosol (ricin A chain; RTA)…”
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The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain by Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P, Roberts, David M, Lord, J Michael, Hartmann-Petersen, Rasmus, Roberts, Lynne M, Spooner, Robert A

“…The plant cytotoxin ricin enters mammalian cells by receptor-mediated endocytosis, undergoing retrograde transport to the ER (endoplasmic reticulum) where its…”
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The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network by Spooner, Robert A, Watson, Peter, Smith, Daniel C, Boal, Frédéric, Amessou, Mohammed, Johannes, Ludger, Clarkson, Guy J, Lord, J Michael, Stephens, David J, Roberts, Lynne M

“…The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to…”
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Ricin A Chain Insertion into Endoplasmic Reticulum Membranes Is Triggered by a Temperature Increase to 37 °C by Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa T.J., Moore, Katherine A.H., Lord, J.Michael, Johnson, Arthur E., Roberts, Lynne M.

“…After endocytic uptake by mammalian cells, the heterodimeric plant toxin ricin is transported to the endoplasmic reticulum (ER), where the ricin A chain (RTA)…”
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Retrograde transport pathways utilised by viruses and protein toxins by Spooner, Robert A, Smith, Daniel C, Easton, Andrew J, Roberts, Lynne M, Lord, J Michael

“…A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with…”
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Disulfide formation in plant storage vacuoles permits assembly of a multimeric lectin by Marshall, Richard S, Frigerio, Lorenzo, Roberts, Lynne M

“…The ER (endoplasmic reticulum) has long been considered the plant cell compartment within which protein disulfide bond formation occurs. Members of the…”
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The Role of CDC48 in the Retro-translocation of Non-ubiquitinated Toxin Substrates in Plant Cells by Marshall, Richard S., Jolliffe, Nicholas A., Ceriotti, Aldo, Snowden, Christopher J., Lord, J. Michael, Frigerio, Lorenzo, Roberts, Lynne M.

“…When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the…”
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Internalized Pseudomonas Exotoxin A can Exploit Multiple Pathways to Reach the Endoplasmic Reticulum by Smith, Daniel C., Spooner, Robert A., Watson, Peter D., Murray, James L., Hodge, Thomas W., Amessou, Mohamed, Johannes, Ludger, Lord, J. Michael, Roberts, Lynne M.

“…Receptor‐mediated internalization to the endoplasmic reticulum (ER) and subsequent retro‐translocation to the cytosol are essential sequential processes…”
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The Low Lysine Content of Ricin A Chain Reduces the Risk of Proteolytic Degradation after Translocation from the Endoplasmic Reticulum to the Cytosol by Deeks, Emma D, Cook, Jonathan P, Day, Philip J, Smith, Daniel C, Roberts, Lynne M, Lord, J. Michael

“…Several protein toxins, including the A chain of ricin (RTA), enter mammalian cells by endocytosis and subsequently reach their cytosolic substrates by…”
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Preeclampsia-Associated Cardiovascular Risk Factors 6 Months and 2 Years After Pregnancy: The P4 Study by Henry, Amanda, Mangos, George, Roberts, Lynne M, Brown, Mark A, Pettit, Franziska, O'Sullivan, Anthony J, Crowley, Rose, Youssef, George, Davis, Gregory K

“…Increased cardiovascular risk following preeclampsia is well established and there are signs of early cardiovascular aging 6 months postpartum. This study…”
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Ricin A Chain without Its Partner B Chain is Degraded after Retrotranslocation from the Endoplasmic Reticulum to the Cytosol in Plant Cells by Di Cola, Alessandra, Frigerio, Lorenzo, Lord, J. Michael, Ceriotti, Aldo, Roberts, Lynne M.

“…When expressed in tobacco cells, the catalytic subunit of the dimeric ribosome inactivating protein, ricin, is first inserted into the endoplasmic reticulum…”
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