Search Results - "ROBERTS, Lewis"
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Hepatocellular carcinoma: a global view
Published in Nature reviews. Gastroenterology & hepatology (01-08-2010)“…Hepatocellular carcinoma is a global health problem, although developing countries are disproportionally affected. About three-quarters of hepatocellular…”
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Untreated Chronic Hepatitis B Is Associated With a Higher Risk of Extrahepatic Malignancies
Published in Journal of clinical oncology (10-10-2022)Get full text
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Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2019)“…The pathogenesis of hepatocellular carcinoma (HCC) is poorly understood, but recent advances in genomics have increased our understanding of the mechanisms by…”
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A global view of hepatocellular carcinoma: trends, risk, prevention and management
Published in Nature reviews. Gastroenterology & hepatology (01-10-2019)“…Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide. Risk factors for HCC include chronic hepatitis B and…”
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Genetics of Hepatocellular Carcinoma: Approaches to Explore Molecular Diversity
Published in Hepatology (Baltimore, Md.) (01-01-2021)Get full text
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p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
Published in Cancer cell (10-10-2016)“…Hepatic stellate cells (HSCs) play critical roles in liver fibrosis and hepatocellular carcinoma (HCC). Vitamin D receptor (VDR) activation in HSCs inhibits…”
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Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
Published in Scientific reports (01-10-2015)“…Hepatocellular carcinoma (HCC) is the second-leading cause of cancer-related death worldwide and the factors influencing HCC progression are poorly understood…”
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Imaging for the diagnosis of hepatocellular carcinoma: A systematic review and meta‐analysis
Published in Hepatology (Baltimore, Md.) (01-01-2018)“…Multiphasic computed tomography (CT) and magnetic resonance imaging (MRI) are both used for noninvasive diagnosis of hepatocellular carcinoma (HCC) in patients…”
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The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets
Published in Seminars in cancer biology (01-02-2011)“…Abstract A growing body of literature highlights the cross-talk between tumor cells and the surrounding peri-tumoral stroma as a key modulator of the processes…”
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Trial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference
Published in Hepatology (Baltimore, Md.) (01-01-2021)Get full text
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Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Published in Nature reviews. Gastroenterology & hepatology (01-09-2020)“…Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence…”
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Chemopreventive strategies in hepatocellular carcinoma
Published in Nature reviews. Gastroenterology & hepatology (01-01-2014)“…Key Points Antiviral therapies directed against HBV and HCV are universally effective in primary and secondary prevention of hepatocellular carcinoma (HCC),…”
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AASLD guidelines for the treatment of hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-01-2018)Get full text
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Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE Study
Published in Liver international (01-09-2015)“…Background & Aims Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths worldwide. The global HCC BRIDGE study was a multiregional,…”
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Diabetes Is Associated With Increased Risk of Hepatocellular Carcinoma in Patients With Cirrhosis From Nonalcoholic Fatty Liver Disease
Published in Hepatology (Baltimore, Md.) (01-03-2020)“…Diabetes increases the risk of liver disease progression and cirrhosis development in patients with nonalcoholic steatohepatitis (NASH). The association…”
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Elevated rates of horizontal gene transfer in the industrialized human microbiome
Published in Cell (15-04-2021)“…Industrialization has impacted the human gut ecosystem, resulting in altered microbiome composition and diversity. Whether bacterial genomes may also adapt to…”
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Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma
Published in Journal of hepatology (01-08-2020)“…Cholangiocarcinoma (CCA), a deadly malignancy of the bile ducts, can be classified based on its anatomical location into either intrahepatic (iCCA) or…”
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A SURVEY OF THE HIGH ORDER MULTIPLICITY OF NEARBY SOLAR-TYPE BINARY STARS WITH Robo-AO
Published in The Astrophysical journal (20-01-2015)“…We conducted a survey of nearby binary systems composed of main sequence stars of spectral types F and Gin order to improve our understanding of the…”
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