Search Results - "ROBERTS, J."
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Therapeutic protein aggregation: mechanisms, design, and control
Published in Trends in biotechnology (Regular ed.) (01-07-2014)“…Highlights • Therapeutic proteins form a variety of aggregate types. • Aggregates are risk factors for patient immune responses. • Aggregation mechanisms…”
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Protein aggregation and its impact on product quality
Published in Current opinion in biotechnology (01-12-2014)“…Graphical abstract…”
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Contribution of elastic tissues to the mechanics and energetics of muscle function during movement
Published in Journal of experimental biology (01-01-2016)“…Muscle force production occurs within an environment of tissues that exhibit spring-like behavior, and this elasticity is a critical determinant of muscle…”
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Protein aggregation – Mechanisms, detection, and control
Published in International journal of pharmaceutics (25-10-2018)“…[Display omitted] Protein aggregation has been recognized as one of the major challenges in the development and commercialization of successful protein-based…”
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Impact of vaccination by priority group on UK deaths, hospital admissions and intensive care admissions from COVID‐19
Published in Anaesthesia (01-05-2021)“…Summary National (and global) vaccination provides an opportunity to control the COVID‐19 pandemic, which disease suppression by societal lockdown and…”
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Climate change and the transition to neoliberal environmental governance
Published in Global environmental change (01-09-2017)“…•Documents five main shifts within UNFCCC and outlines core governance practices for each phase.•Offers an analytical framework to assess the extent of…”
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Concepts and misconceptions in corneal biomechanics
Published in Journal of cataract and refractive surgery (01-06-2014)“…This review looks at biomechanical concepts and misconceptions related to in vivo assessment of corneal biomechanical response via air-puff deformation,…”
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Explaining differential vulnerability to climate change: A social science review
Published in Wiley interdisciplinary reviews. Climate change (01-03-2019)“…The varied effects of recent extreme weather events around the world exemplify the uneven impacts of climate change on populations, even within relatively…”
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Identifying Supply and Demand Elasticities of Agricultural Commodities: Implications for the US Ethanol Mandate
Published in The American economic review (01-10-2013)“…We present a new framework to identify supply elasticities ofstorable commodities where past shocks are used as exogenous price shifters. In the agricultural…”
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Emerging mechanisms of dynein transport in the cytoplasm versus the cilium
Published in Biochemical Society transactions (20-08-2018)“…Two classes of dynein power long-distance cargo transport in different cellular contexts. Cytoplasmic dynein-1 is responsible for the majority of transport…”
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Nonlinear temperature effects indicate severe damages to U.S. crop yields under climate change
Published in Proceedings of the National Academy of Sciences - PNAS (15-09-2009)“…The United States produces 41% of the world's corn and 38% of the world's soybeans. These crops comprise two of the four largest sources of caloric energy…”
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Twenty-five years of adaptation finance through a climate justice lens
Published in Climatic change (01-07-2020)“…How much finance should be provided to support climate change adaptation and by whom? How should it be allocated, and on what basis? Over the years, various…”
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13
Reefs of the Deep: The Biology and Geology of Cold-Water Coral Ecosystems
Published in Science (American Association for the Advancement of Science) (28-04-2006)“…Coral reefs are generally associated with shallow tropical seas; however, recent deep-ocean exploration using advanced acoustics and submersibles has revealed…”
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14
Use of Exploratory Factor Analysis in Published Research: Common Errors and Some Comment on Improved Practice
Published in Educational and psychological measurement (01-06-2006)“…Given the proliferation of factor analysis applications in the literature, the present article examines the use of factor analysis in current published…”
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From constraint to sufficiency: The decoupling of energy and carbon from human needs, 1975–2005
Published in Ecological economics (01-12-2010)“…We investigate the relationship between human needs, energy consumption and carbon emissions for several indicators of human development: life expectancy,…”
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Flexible mechanisms: the diverse roles of biological springs in vertebrate movement
Published in Journal of experimental biology (01-02-2011)“…The muscles that power vertebrate locomotion are associated with springy tissues, both within muscle and in connective tissue elements such as tendons. These…”
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Non-native protein aggregation kinetics
Published in Biotechnology and bioengineering (01-12-2007)“…Experimental kinetics of non-native protein aggregation are of practical importance in that they help dictate viable processing, formulation, and storage…”
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Environmental Justice
Published in Annual review of environment and resources (01-01-2009)“…The article reviews two decades of scholars' claims that exposures to pollution and other environmental risks are unequally distributed by race and class,…”
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Reductions in global biodiversity loss predicted from conservation spending
Published in Nature (London) (16-11-2017)“…Empirical two-part models describe the relationship between conservation spending, human development pressures and biodiversity loss and can inform sustainable…”
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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
Published in Oncogene (14-05-2007)“…Mitogen-activated protein kinase (MAPK) cascades are key signaling pathways involved in the regulation of normal cell proliferation, survival and…”
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