Search Results - "RISIN, DIANA"

The current state of bone loss research: Data from spaceflight and microgravity simulators by Nagaraja, Mamta Patel, Risin, Diana

“…Bone loss is a well documented phenomenon occurring in humans both in short‐ and in long‐term spaceflights. This phenomenon can be also reproduced on the…”
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Identification of mechanosensitive genes in osteoblasts by comparative microarray studies using the rotating wall vessel and the random positioning machine by Patel, Mamta J., Liu, Wenbin, Sykes, Michelle C., Ward, Nancy E., Risin, Semyon A., Risin, Diana, Jo, Hanjoong

“…Weightlessness or microgravity of spaceflight induces bone loss due in part to decreased bone formation by unknown mechanisms. Due to difficulty in performing…”
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LOSS OF SIGNAL TRANSDUCTION AND INHIBITION OF LYMPHOCYTE LOCOMOTION IN A GROUND-BASED MODEL OF MICROGRAVITY by SUNDARESAN, ALAMELU, RISIN, DIANA, PELLIS, NEAL R

“…Inflammatory adherence to, and locomotion through the interstitium is an important component of the immune response. Conditions such as microgravity and…”
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Induction of Three-Dimensional Assembly of Human Liver Cells by Simulated Microgravity by Vladimir I. Khaoustov, Darlington, Gretchen J., Soriano, Humberto E., Bhuvaneswari Krishnan, Diana Risin, Pellis, Neal R., Yoffe, Boris

“…The establishment of long-term cultures of functional primary human liver cells (PHLC) is formidable. Developed at NASA, the Rotary Cell Culture System (RCCS)…”
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Modeled Microgravity Inhibits Apoptosis in Peripheral Blood Lymphocytes by Diana Risin, Pellis, Neal R.

“…Microgravity interferes with numerous lymphocyte functions (expression of cell surface molecules, locomotion, polyclonal and antigen-specific activation, and…”
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SUPPRESSION OF ANTIGEN-SPECIFIC LYMPHOCYTE ACTIVATION IN MODELED MICROGRAVITY by COOPER, DAVID, PRIDE, MICHAEL W, BROWN, ERIC L, RISIN, DIANA, PELLIS, NEAL R

“…Various parameters of immune suppression are observed in lymphocytes from astronauts during and after a space flight. It is difficult to ascribe this…”
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Changes in Gravity Inhibit Lymphocyte Locomotion through Type I Collagen by Pellis, Neal R., Thomas J. Goodwin, Diana Risin, McIntyre, Bradley W., Roland P. Pizzini, Cooper, David, Tacey L. Baker, Glenn F. Spaulding

“…Immunity relies on the circulation of lymphocytes through many different tissues including blood vessels, lymphatic channels, and lymphoid organs. The ability…”
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MICROARRAY ANALYSIS OF GENES DIFFERENTIALLY EXPRESSED IN HEPG2 CELLS CULTURED IN SIMULATED MICROGRAVITY: PRELIMINARY REPORT by KHAOUSTOV, VLADIMIR I, RISIN, DIANA, PELLIS, NEAL R, YOFFE, BORIS

“…Developed at NASA, the rotary cell culture system (RCCS) allows the creation of unique microgravity environment of low shear force, high-mass transfer, and…”
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Gene expression alterations in activated human T-cells induced by modeled microgravity by Ward, Nancy E., Pellis, Neal R., Risin, Semyon A., Risin, Diana

“…Studies conducted in real Space and in ground‐based microgravity analog systems (MAS) have demonstrated changes in numerous lymphocyte functions. In this…”
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Gene Expression Profiles of 2T3 Preosteoblasts in Microgravity Analog Systems: Comparison of the Random Positioning Machine and the Rotating Wall Vessel Bioreactor by Patel, Mamta J, Risin, Diana, Jo, Hanjoong

“…We have previously shown that 2T3 preosteoblasts exposed to simulated microgravity using the Random Positioning Machine (RPM) experienced changes in gene…”
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MODELED MICROGRAVITY INHIBITS APOPTOSIS IN PERIPHERAL BLOOD LYMPHOCYTES1 by RISIN, DIANA, PELLIS, NEAL R

“…Microgravity interferes with numerous lymphocyte functions (expression of cell surface molecules, locomotion, polyclonal and antigen-specific activation, and…”
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Changes in expression of genes involved in apoptosis in activated human T-cells in response to modeled microgravity by Ward, Nancy E, Pellis, Neal R, Risin, Diana, Risin, Semyon A, Liu, Wenbin

“…Space flights result in remarkable effects on various physiological systems, including a decline in cellular immune functions. Previous studies have shown that…”
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Locomotion of lymphocytes towards melanoma cells treated with tumor necrosis factor in a syngeneic in vitro model by Gutman, H, Laish-Farkash, A, Risin, D, Pellis, N R

“…Tumor necrosis factor (TNF) causes cell necrosis in vivo by damaging the endothelium of the neovasculature. However, its mechanism of action is not well…”
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Impairment of lymphocyte locomotion in the tumor microenvironment and the effect of systemic immunotherapy with liposome-encapsulated myramyl-tripeptide-phosphatidylethanolamine by Risin, Diana, Kleinerman, Eugenie S., Umezu, Yasuiki, Pizzini, Roland P., Balch, Charles M., Pellis, Neal R.

“…The ability of the lymphocytes to move through the interstitium is obligatory to the immune response. We previously showed that tumor-infiltrating lymphocytes…”
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Effect of surgery on peripheral blood lymphocyte locomotion through type I collagen by Gutman, H, Risin, D, Pollock, R E, Pellis, N R

“…Locomotion of peripheral blood lymphocytes (PBL) through peritumoral matrix is obligatory for tumor cell killing. The authors investigated the effect of…”
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