Search Results - "RIPELLINO, J. A"

Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase by ROBERTS, S. B, RIPELLINO, J. A, INGALLS, K. M, ROBAKIS, N. K, FELSENSTEIN, K. M

“…The beta-amyloid precursor protein (beta-APP) is a membrane spanning glycoprotein. The small beta-protein domain within the precursor is presumed to be the…”
Get full text

Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum by RIPELLINO, J. A, NEVE, R. L, HOWE, J. R

“…The localization and expression of ionotropic non-N-methyl-D-aspartate glutamate receptors (GluR) were investigated in the developing and adult rat cerebellum…”
Get full text

Chondroitin sulfate proteoglycan form of the Alzheimer's beta-amyloid precursor by SHIOI, J, ANDERSON, J. P, RIPELLINO, J. A, ROBAKIS, N. K

“…The Alzheimer's amyloid beta protein is derived from a family of membrane glycoproteins termed amyloid precursor proteins (APP). Here we show that APP exists…”
Get full text

Cholinergic Agonists Stimulate Secretion of Soluble Full-Length Amyloid Precursor Protein in Neuroendocrine Cells by Efthimiopoulos, Spiros, Vassilacopoulou, Dido, Ripellino, James A., Tezapsidis, Nikolaos, Robakis, Nikolaos K.

“…The Aβ peptide of Alzheimer disease is derived from the proteolytic processing of the amyloid precursor proteins (APP), which are considered type I…”
Get full text

Hyaluronate Accumulation in Human Epidermis Treated with Retinoic Acid in Skin Organ Culture by Tammi, Raija, Ripellino, James A., Margolis, Richard U., Maibach, Howard I., Tammi, Markku

“…Retinoic acid (RA) has been shown to retard the differentiation of epidermal keratinocytes by several morphologic and biochemical criteria. In this study, the…”
Get full text

The hyaluronic acid binding region as a specific probe for the localization of hyaluronic acid in tissue sections. Application to chick embryo and rat brain by Ripellino, J A, Klinger, M M, Margolis, R U, Margolis, R K

“…The hyaluronic acid binding region was prepared by clostripain digestion of chondroitin sulfate proteoglycan isolated from the Swarm rat chondrosarcoma, and…”
Get full text

Solubilization of full-length amyloid precursor proteins from PC12 cell membranes by Ripellino, J A, Vassilacopoulou, D, Robakis, N K

“…The amyloid beta protein (A beta) of Alzheimer disease (AD) is derived from the proteolytic processing of the amyloid precursor proteins (APP), which are…”
Get more information

Immunoelectron Microscopic Localization of Hyaluronic Acid-Binding Region and Link Protein Epitopes in Brain by Ripellino, J. A., Margolis, R. U., Margolis, R. K.

“…The 1C6 monoclonal antibody to the hyaluronic acid-binding region weakly stained a 65-kD component in immunoblots of the chondroitin sulfate proteoglycans of…”
Get full text

Light and Electron Microscopic Studies on the Localization of Hyaluronic Acid in Developing Rat Cerebellum by Ripellino, J. A., Bailo, M., Margolis, R. U., Margolis, R. K.

“…The hyaluronic acid-binding region was prepared by trypsin digestion of chondroitin sulfate proteoglycan aggregate from the Swarm rat chondrosarcoma, and…”
Get full text

Localization of Epidermal Hyaluronic Acid Using the Hyaluronate Binding Region of Cartilage Proteoglycan as a Specific Probe by Tammi, Raija, Ripellino, James A., Margolis, Richard U., Tammi, Markku

“…Hyaluronate is actively synthesized by cultured epidermis and dermis, but no direct histological data have been available about its localization in normal…”
Get full text

Full-length and truncated Alzheimer amyloid precursors in chromaffin granules: solubilization of membrane amyloid precursor is mediated by an enzymatic mechanism by Vassilacopoulou, D, Ripellino, J A, Tezapsidis, N, Hook, V Y, Robakis, N K

“…The amyloid beta peptide (A beta) of Alzheimer disease is derived from the proteolytic processing of the amyloid precursor proteins (APPs), which are…”
Get more information

Occurrence of the HNK-1 epitope (3-sulfoglucuronic acid) in PC12 pheochromocytoma cells, chromaffin granule membranes, and chondroitin sulfate proteoglycans by Margolis, R K, Ripellino, J A, Goossen, B, Steinbrich, R, Margolis, R U

“…After biosynthetic labeling of sulfated glycoproteins in rat and goldfish brain and PC12 pheochromocytoma cells with sodium [35S]sulfate, it was observed that…”
Get more information

Oligosaccharide composition, localization, and developmental changes of a CNS-specific (F3-87-8) glycoprotein by Ripellino, J A, Margolis, R U, Margolis, R K

“…The F3-87-8 glycoprotein was isolated from rat brain by immunoaffinity chromatography after biosynthetic labeling by intracerebral administration of…”
Get more information

Structural properties of the heparan sulfate proteoglycans of brain by Ripellino, J A, Margolis, R U

“…The heparan sulfate proteoglycans present in a deoxycholate extract of rat brain were purified by ion exchange chromatography, affinity chromatography on…”
Get more information

Expression and heteromeric interactions of non- N-methyl- d-aspartate glutamate receptor subunits in the developing and adult cerebellum by Ripellino, J.A, Neve, R.L, Howe, J.R

“…The localization and expression of ionotropic non- N-methyl- d-aspartate glutamate receptors (GluR) were investigated in the developing and adult rat…”
Get full text

High-affinity kainate-type ion channels in rat cerebellar granule cells by Pemberton, Karen E., Belcher, Scott M., Ripellino, James A., Howe, James R.

“…Patch-clamp recordings were made from rat cerebellar granule cells in primary culture. In cells pre-exposed to concanavalin A (ConA) to remove kainate receptor…”
Get full text

Association of axonally transported heparan sulfate with isolated synaptic plasma membrane by ELAM, J. S, RIPELLINO, J. A

“…Studies on isolated synaptic plasma membranes (SPM) have detected little if any heparan sulfate or other glycosaminoglycans (GAGs), while more recent studies…”
Get full text

Axonal transport of proteoglycans to the goldfish optic tectum by RIPELLINO, J. A, ELAM, J. S

“…The study addressed the question of whether 35SO4 labeled molecules that have been delivered to the goldfish optic nerve terminals by rapid axonal transport…”
Get full text

Structure and localization of nervous tissue proteoglycans by Margolis, R U, Aquino, D A, Klinger, M M, Ripellino, J A, Margolis, R K

Get more information

The Alzheimer Amyloid Precursor Proteoglycan (Appican) Is Present in Brain and Is Produced by Astrocytes but Not by Neurons in Primary Neural Cultures by Shioi, Junichi, Pangalos, Menelas N., Ripellino, James A., Vassilacopoulou, Dido, Mytilineou, Catherine, Margolis, Richard U., Robakis, Nikolaos K.

“…Recent studies showed that the Alzheimer amyloid precursor (APP) occurs as the core protein of a chondroitin sulfate proteoglycan (appican) in C6 glioma cells…”
Get full text