Search Results - "RING, Susan"

Systematic identification of genetic influences on methylation across the human life course by Gaunt, Tom R, Shihab, Hashem A, Hemani, Gibran, Min, Josine L, Woodward, Geoff, Lyttleton, Oliver, Zheng, Jie, Duggirala, Aparna, McArdle, Wendy L, Ho, Karen, Ring, Susan M, Evans, David M, Davey Smith, George, Relton, Caroline L

“…The influence of genetic variation on complex diseases is potentially mediated through a range of highly dynamic epigenetic processes exhibiting temporal…”
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Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) by Richmond, Rebecca C, Simpkin, Andrew J, Woodward, Geoff, Gaunt, Tom R, Lyttleton, Oliver, McArdle, Wendy L, Ring, Susan M, Smith, Andrew D A C, Timpson, Nicholas J, Tilling, Kate, Davey Smith, George, Relton, Caroline L

“…Maternal smoking during pregnancy has been found to influence newborn DNA methylation in genes involved in fundamental developmental processes. It is pertinent…”
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Cohort Profile: The 'Children of the 90s'—the index offspring of the Avon Longitudinal Study of Parents and Children by BOYD, Andy, GOLDING, Jean, MACLEOD, John, LAWLOR, Debbie A, FRASER, Abigail, HENDERSON, John, MOLLOY, Lynn, NESS, Andy, RING, Susan, SMITH, George Davey

“…The Avon Longitudinal Study of Parents and Children (ALSPAC) is a transgenerational prospective observational study investigating influences on health and…”
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Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children by Sharp, Gemma C, Lawlor, Debbie A, Richmond, Rebecca C, Fraser, Abigail, Simpkin, Andrew, Suderman, Matthew, Shihab, Hashem A, Lyttleton, Oliver, McArdle, Wendy, Ring, Susan M, Gaunt, Tom R, Davey Smith, George, Relton, Caroline L

“…Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a…”
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Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis by Thompson, William D, Tyrrell, Jessica, Borges, Maria-Carolina, Beaumont, Robin N, Knight, Bridget A, Wood, Andrew R, Ring, Susan M, Hattersley, Andrew T, Freathy, Rachel M, Lawlor, Debbie A

“…Systematic reviews of randomised controlled trials (RCTs) have suggested that maternal vitamin D (25[OH]D) and calcium supplementation increase birth weight…”
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DNA methylation patterns in cord blood DNA and body size in childhood by Relton, Caroline L, Groom, Alexandra, St Pourcain, Beate, Sayers, Adrian E, Swan, Daniel C, Embleton, Nicholas D, Pearce, Mark S, Ring, Susan M, Northstone, Kate, Tobias, Jon H, Trakalo, Joseph, Ness, Andy R, Shaheen, Seif O, Davey Smith, George

“…Epigenetic markings acquired in early life may have phenotypic consequences later in development through their role in transcriptional regulation with…”
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The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort by Simpkin, Andrew J, Howe, Laura D, Tilling, Kate, Gaunt, Tom R, Lyttleton, Oliver, McArdle, Wendy L, Ring, Susan M, Horvath, Steve, Smith, George Davey, Relton, Caroline L

“…Statistical models that use an individual's DNA methylation levels to estimate their age (known as epigenetic clocks) have recently been developed, with 96%…”
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Common variants in left/right asymmetry genes and pathways are associated with relative hand skill by Brandler, William M, Morris, Andrew P, Evans, David M, Scerri, Thomas S, Kemp, John P, Timpson, Nicholas J, St Pourcain, Beate, Smith, George Davey, Ring, Susan M, Stein, John, Monaco, Anthony P, Talcott, Joel B, Fisher, Simon E, Webber, Caleb, Paracchini, Silvia

“…Humans display structural and functional asymmetries in brain organization, strikingly with respect to language and handedness. The molecular basis of these…”
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A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci by Hinds, David A, McMahon, George, Kiefer, Amy K, Do, Chuong B, Eriksson, Nicholas, Evans, David M, St Pourcain, Beate, Ring, Susan M, Mountain, Joanna L, Francke, Uta, Davey-Smith, George, Timpson, Nicholas J, Tung, Joyce Y

“…David Hinds and colleagues report results of a genome-wide association meta-analysis of self-reported allergy. They identify 16 shared susceptibility loci for…”
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Genome-wide Association Study of Three-Dimensional Facial Morphology Identifies a Variant in PAX3 Associated with Nasion Position by Paternoster, Lavinia, Zhurov, Alexei I., Toma, Arshed M., Kemp, John P., St. Pourcain, Beate, Timpson, Nicholas J., McMahon, George, McArdle, Wendy, Ring, Susan M., Smith, George Davey, Richmond, Stephen, Evans, David M.

“…Craniofacial morphology is highly heritable, but little is known about which genetic variants influence normal facial variation in the general population. We…”
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Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies by Simpkin, Andrew J, Hemani, Gibran, Suderman, Matthew, Gaunt, Tom R, Lyttleton, Oliver, Mcardle, Wendy L, Ring, Susan M, Sharp, Gemma C, Tilling, Kate, Horvath, Steve, Kunze, Sonja, Peters, Annette, Waldenberger, Melanie, Ward-Caviness, Cavin, Nohr, Ellen A, Sørensen, Thorkild I A, Relton, Caroline L, Smith, George Davey

“…DNA methylation-based biomarkers of aging are highly correlated with actual age. Departures of methylation-estimated age from actual age can be used to define…”
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DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework by Richmond, Rebecca C, Sharp, Gemma C, Ward, Mary E, Fraser, Abigail, Lyttleton, Oliver, McArdle, Wendy L, Ring, Susan M, Gaunt, Tom R, Lawlor, Debbie A, Davey Smith, George, Relton, Caroline L

“…Multiple differentially methylated sites and regions associated with adiposity have now been identified in large-scale cross-sectional studies. We tested for…”
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Assessment of rates of recanting and hair testing as a biological measure of drug use in a general population sample of young people by Taylor, Michelle, Sullivan, John, Ring, Susan M., Macleod, John, Hickman, Matthew

“…Aims We investigate the extent of and factors associated with denial of previously reported cannabis and other illicit drug use, and assess the potential of…”
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Longitudinal analysis of DNA methylation associated with birth weight and gestational age by Simpkin, Andrew J, Suderman, Matthew, Gaunt, Tom R, Lyttleton, Oliver, McArdle, Wendy L, Ring, Susan M, Tilling, Kate, Davey Smith, George, Relton, Caroline L

“…Gestational age (GA) and birth weight have been implicated in the determination of long-term health. It has been hypothesized that changes in DNA methylation…”
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Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth by Elks, Cathy E, Loos, Ruth J F, Sharp, Stephen J, Langenberg, Claudia, Ring, Susan M, Timpson, Nicholas J, Ness, Andrew R, Davey Smith, George, Dunger, David B, Wareham, Nicholas J, Ong, Ken K

“…Genome-wide studies have identified several common genetic variants that are robustly associated with adult obesity risk. Exploration of these genotype…”
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Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age by Lee, Ken W K, Richmond, Rebecca, Hu, Pingzhao, French, Leon, Shin, Jean, Bourdon, Celine, Reischl, Eva, Waldenberger, Melanie, Zeilinger, Sonja, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Woodward, Geoff, Bouchard, Luigi, Gaudet, Daniel, Smith, George Davey, Relton, Caroline, Paus, Tomas, Pausova, Zdenka

“…Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure) had been associated with altered DNA methylation (DNAm) at birth. We examined whether…”
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Prevalence of Mitochondrial 1555A→G Mutation in European Children by Heron, Jon, Bitner-Glindzicz, Maria, Rahman, Shamima, Pembrey, Marcus, Ring, Susan M, Hall, Amanda, Duncan, Andrew

“…To the Editor: Aminoglycoside antibiotics are used worldwide to treat gram-negative sepsis. Since these drugs are ototoxic and nephrotoxic, drug levels are…”
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Maternal thyroid function and child educational attainment: prospective cohort study by Nelson, Scott M, Haig, Caroline, McConnachie, Alex, Sattar, Naveed, Ring, Susan M, Smith, George D, Lawlor, Debbie A, Lindsay, Robert S

“…AbstractObjectiveTo determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational…”
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Alleles of a Polymorphic ETV6 Binding Site in DCDC2 Confer Risk of Reading and Language Impairment by Powers, Natalie R., Eicher, John D., Butter, Falk, Kong, Yong, Miller, Laura L., Ring, Susan M., Mann, Matthias, Gruen, Jeffrey R.

“…Reading disability (RD) and language impairment (LI) are common learning disabilities that make acquisition and utilization of reading and verbal language…”
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Programming of adiposity in childhood and adolescence: associations with birth weight and cord blood adipokines by Simpson, Joy, Smith, Andrew DAC, Fraser, Abigail, Sattar, Naveed, Lindsay, Robert S, Ring, Susan M, Tilling, Kate, Davey Smith, George, Lawlor, Debbie A, Nelson, Scott M

“…Context:Exposure to maternal adiposity during pregnancy is associated with higher offspring birthweight and greater adiposity through childhood and adult life…”
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