Search Results - "RING, B"

Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells by Zhang, Y, Gong, Y, Hu, D, Zhu, P, Wang, N, Zhang, Q, Wang, M, Aldeewan, A, Xia, H, Qu, X, Ring, B Z, Minato, N, Su, L

“…SIPA1 (signal-induced proliferation-associated protein 1) is a GTPase activation protein that can catalyze the hydrolysis of Rap1 bound GTP to GDP. Recently…”
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Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3 by Wagman, Allan S, Boyce, Rustum S, Brown, Sean P, Fang, Eric, Goff, Dane, Jansen, Johanna M, Le, Vincent P, Levine, Barry H, Ng, Simon C, Ni, Zhi-Jie, Nuss, John M, Pfister, Keith B, Ramurthy, Savithri, Renhowe, Paul A, Ring, David B, Shu, Wei, Subramanian, Sharadha, Zhou, Xiaohui A, Shafer, Cynthia M, Harrison, Stephen D, Johnson, Kirk W, Bussiere, Dirksen E

“…In an effort to identify new antidiabetic agents, we have discovered a novel family of…”
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Nuclear SIPA1 activates integrin beta 1 promoter and promotes invasion of breast cancer cells by Zhang, Y, Gong, Y, Hu, D, Zhu, P, Wang, N, Zhang, Q, Wang, M, Aldeewan, A, Xia, H, Qu, X, Ring, B Z, Minato, N, Su, L

“…SIPA1 (signal-induced proliferation-associated protein 1) is a GTPase activation protein that can catalyze the hydrolysis of Rap1 bound GTP to GDP. Recently…”
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Selective Glycogen Synthase Kinase 3 Inhibitors Potentiate Insulin Activation of Glucose Transport and Utilization In Vitro and In Vivo by RING, David B, JOHNSON, Kirk W, WAGMAN, Allan S, HAMMOND, Mary-Ellen Wernette, HARRISON, Stephen D, HENRIKSEN, Erik J, NUSS, John M, GOFF, Dane, KINNICK, Tyson R, MA, Sylvia T, REEDER, John W, SAMUELS, Isa, SLABIAK, Trina

“…Selective Glycogen Synthase Kinase 3 Inhibitors Potentiate Insulin Activation of Glucose Transport and Utilization In Vitro and In Vivo David B. Ring 1 , Kirk…”
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Predicting energy expenditure from accelerometry counts in adolescent girls by SCHMITZ, Kathryn H, TREUTH, Margarita, HANNAN, Peter, MCMURRAY, Robert, RING, Kimberly B, CATELLIER, Diane, PATE, Russ

“…Calibration of accelerometer counts against oxygen consumption to predict energy expenditure has not been conducted in middle school girls. We concurrently…”
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Comparison of two approaches to structured physical activity surveys for adolescents by MCMURRAY, Robert G, RING, Kimberly B, SALLIS, James F, TREUTH, Margarita S, WELK, Gregory J, PATE, Russell R, SCHMITZ, Kathryn H, PICKREL, Julie L, GONZALEZ, Vivian, ALMEDIA, M. Jaoa C. A, YOUNG, Deborah Rohm

“…To compare the test-retest reliability, convergent validity, and overall feasibility/ usability of activity-based (AB) and time-based (TB) approaches for…”
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Three- and Four-Dimensional-Quantitative Structure Activity Relationship (3D/4D-QSAR) Analyses of CYP2C9 Inhibitors by EKINS, S, BRAVI, G, BINKLEY, S, GILLESPIE, J. S, RING, B. J, WIKEL, J. H, WRIGHTON, S. A

“…The interaction of competitive type inhibitors with the active site of cytochrome P450 (CYP) 2C9 has been predicted using three- and four-dimensional…”
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Novel EDA p.Ile260Ser Mutation Linked to Non-syndromic Hypodontia by Yang, Y., Luo, L., Xu, J., Zhu, P., Xue, W., Wang, J., Li, W., Wang, M., Cheng, K., Liu, S., Tang, Z., Ring, B.Z., Su, L.

“…Hypodontia, a tooth developmental disease, can affect chewing and pronunciation. Mutations in the ectodysplasin-A (EDA) gene can lead to both X-linked…”
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Effect of Tadalafil on Cytochrome P450 3A4-mediated Clearance: Studies in Vitro and in Vivo by Ring, Barbara J., Patterson, Beverley E., Mitchell, Malcolm I., Vandenbranden, Mark, Gillespie, Jennifer, Bedding, Alun W., Jewell, Hayley, Payne, Christopher D., Forgue, S. Thomas, Eckstein, James, Wrighton, Steven A., Phillips, Diane L.

“…Objectives Tadalafil was examined in vitro and in vivo for its ability to affect human cytochrome P450 (CYP) 3A‐mediated metabolism. Methods Reversible and…”
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Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia by Danilenko, DM, Ring, BD, Yanagihara, D, Benson, W, Wiemann, B, Starnes, CO, Pierce, GF

“…The growth and development of hair follicles is influenced by a number of different growth factors and cytokines, particularly members of the fibroblast growth…”
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CHILD: A First Step Towards Continual Learning by Ring, Mark B

“…Continual learning is the constant development of increasingly complex behaviors; the process of building more complicated skills on top of those already…”
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Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine by WRIGHTON, S. A, RING, B. J

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Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice by Ring, B D, Scully, S, Davis, C R, Baker, M B, Cullen, M J, Pelleymounter, M A, Danilenko, D M

“…Leptin is a 16 kD protein that is produced by adipocytes and induces weight loss in both normal and genetically obese ob/ob mice. ob/ob mice are obese, have…”
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Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless by Min, H, Danilenko, D M, Scully, S A, Bolon, B, Ring, B D, Tarpley, J E, DeRose, M, Simonet, W S

“…Fgf-10-deficient mice (Fgf-10(-/-)) were generated to determine the role(s) of Fgf-10 in vertebrate development. Limb bud initiation was abolished in…”
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Capillary transfer constant of Gd-DTPA in the myocardium at rest and during vasodilation assessed by MRI by Fritz-Hansen, T, Rostrup, E, Søndergaard, L, Ring, P B, Amtorp, O, Larsson, H B

“…The purpose of this study was to determine whether the capillary transfer constant (Ki) of gadolinium-DTPA was sensitive to perfusion changes and whether…”
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Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine by Ring, B J, Catlow, J, Lindsay, T J, Gillespie, T, Roskos, L K, Cerimele, B J, Swanson, S P, Hamman, M A, Wrighton, S A

“…The formation kinetics of 2-hydroxymethyl olanzapine (2-OH olanzapine), 4'-N-oxide olanzapine (N-O olanzapine) and 4'-N-desmethyl olanzapine (NdM olanzapine)…”
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Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine by Ring, B J, Eckstein, J A, Gillespie, J S, Binkley, S N, VandenBranden, M, Wrighton, S A

“…The formation of R- and S-norfluoxetine was analyzed in vitro in human liver microsomes. Low apparent K(m) values for R-norfluoxetine formation of < or =8…”
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The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature Osteoclasts by Burgess, Teresa L., Qian, Yi-xin, Kaufman, Stephen, Ring, Brian D., Van, Gwyneth, Capparelli, Charles, Kelley, Michael, Hsu, Hailing, Boyle, William J., Dunstan, Colin R., Hu, Sylvia, Lacey, David L.

“…Osteoprotegerin (OPG) and OPG-ligand (OPGL) potently inhibit and stimulate, respectively, osteoclast differentiation (Simonet, W.S., D.L. Lacey, C.R. Dunstan,…”
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Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract by Housley, R M, Morris, C F, Boyle, W, Ring, B, Biltz, R, Tarpley, J E, Aukerman, S L, Devine, P L, Whitehead, R H, Pierce, G F

“…Keratinocyte growth factor (KGF), a member of the fibroblast growth factor (FGF) family, was identified as a specific keratinocyte mitogen after isolation from…”
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Autoactivation and activation of the cytochrome P450s by Ekins, S, Ring, B J, Binkley, S N, Hall, S D, Wrighton, S A

“…In order to reliably predict in vivo pharmacokinetic parameters from in vitro data, we must thoroughly understand the systems we currently use to determine…”
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