Search Results - "RINDI, Simonetta"
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Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases
Published in Frontiers in cellular and infection microbiology (05-05-2017)“…Neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against…”
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Streptococcus agalactiae Non-Pilus, Cell Wall-Anchored Proteins: Involvement in Colonization and Pathogenesis and Potential as Vaccine Candidates
Published in Frontiers in immunology (05-04-2018)“…Group B (GBS) remains an important etiological agent of several infectious diseases including neonatal septicemia, pneumonia, meningitis, and orthopedic device…”
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Mechanical Strength and Inhibition of the Staphylococcus aureus Collagen-Binding Protein Cna
Published in mBio (25-10-2016)“…The bacterial pathogen Staphylococcus aureus expresses a variety of cell surface adhesion proteins that bind to host extracellular matrix proteins. Among…”
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Antibody-Based Agents in the Management of Antibiotic-Resistant Staphylococcus aureus Diseases
Published in Microorganisms (Basel) (13-03-2018)“…is a human pathogen that can cause a wide spectrum of diseases, including sepsis, pneumonia, arthritis, and endocarditis. Ineffective treatment of a number of…”
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Fibronectin-binding protein B variation in Staphylococcus aureus
Published in BMC microbiology (01-06-2010)“…Fibronectin binding proteins A and B (FnBPA and FnBPB) mediate adhesion of S. aureus to fibrinogen, elastin and fibronectin. We previously identified seven…”
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SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion
Published in Infection and immunity (01-07-2014)“…Group A streptococcus (GAS) is a human pathogen causing a wide repertoire of mild and severe diseases for which no vaccine is yet available. We recently…”
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Solubility and pH of direct pulp capping materials: a comparative study
Published in Journal of applied biomaterials & functional materials (04-07-2015)“…The objective of the present study was to compare solubility and pH of 6 direct pulp capping materials. Specimens of each material - i.e., Dycal, Calcicur,…”
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Immunogenic properties of Streptococcus agalactiae FbsA fragments
Published in PloS one (24-09-2013)“…Several species of Gram-positive bacteria can avidly bind soluble and surface-associated fibrinogen (Fng), a property that is considered important in the…”
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The presence of both bone sialoprotein-binding protein gene and collagen adhesin gene as a typical virulence trait of the major epidemic cluster in isolates from orthopedic implant infections
Published in Biomaterials (01-12-2009)“…Abstract Staphylococcus aureus is a major, highly clonal, pathogen causing implant infections. This study aimed at investigating the diverse distribution of…”
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Prevention and treatment of Staphylococcus biofilms
Published in Current medicinal chemistry (01-12-2008)“…Staphylococcus growth on medical devices represents a common occurrence that can lead to serious illness and death. Biomaterial-associated infection, mostly…”
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Molecular Characterization of the Multiple Interactions of SpsD, a Surface Protein from Staphylococcus pseudintermedius, with Host Extracellular Matrix Proteins
Published in PloS one (21-06-2013)“…Staphylococcus pseudintermedius, a commensal and pathogen of dogs and occasionally of humans, expresses surface proteins potentially involved in host…”
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Capturing host-pathogen interactions by protein microarrays: identification of novel streptococcal proteins binding to human fibronectin, fibrinogen, and C4BP
Published in The FASEB journal (01-09-2009)“…Microbial pathogen entry and survival in the host is mediated by a network of molecular interactions between the two partners, which has been the subject of…”
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Purification of Human Plasma/Cellular Fibronectin and Fibronectin Fragments
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…A method is described for the purification of plasma fibronectins based on a combination of gelatin- and arginine-Sepharose chromatography steps. Cellular…”
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Single-Cell and Single-Molecule Analysis Unravels the Multifunctionality of the Staphylococcus aureus Collagen-Binding Protein Cna
Published in ACS nano (28-02-2017)“…The collagen-binding protein Cna is a prototype cell surface protein from Staphylococcus aureus which fulfils important physiological functions during…”
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The Group B Streptococcus-Secreted Protein CIP Interacts with C4, Preventing C3b Deposition via the Lectin and Classical Complement Pathways
Published in The Journal of immunology (1950) (01-01-2016)“…The group B Streptococcus (GBS) is a leading cause of neonatal invasive disease. GBS bacteria are surrounded by a thick capsular polysaccharide that is a…”
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Monoclonal Antibodies to CNA, a Collagen-binding Microbial Surface Component Recognizing Adhesive Matrix Molecules, DetachStaphylococcus aureus from a Collagen Substrate
Published in The Journal of biological chemistry (22-12-2000)“…Previous studies showed that Staphylococcus aureus expresses a collagen-binding MSCRAMM (Microbial Surface Component Recognizing Adhesive Matrix Molecules),…”
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Structural and functional role of Staphylococcus aureus surface components recognizing adhesive matrix molecules of the host
Published in Future microbiology (01-12-2009)“…Staphylococcus aureus is a versatile and harmful human pathogen in both hospital- and community-acquired infections. S. aureus can initiate host infection by…”
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IsdC from Staphylococcus lugdunensis induces biofilm formation under low-iron growth conditions
Published in Infection and immunity (01-06-2014)“…Staphylococcus lugdunensis is a coagulase-negative staphylococcus that is a commensal of humans and an opportunistic pathogen. It can cause a spectrum of…”
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Fibronectin Binding Proteins SpsD and SpsL Both Support Invasion of Canine Epithelial Cells by Staphylococcus pseudintermedius
Published in Infection and immunity (01-10-2015)“…In this study, we investigated the cell wall-anchored fibronectin-binding proteins SpsD and SpsL from the canine commensal and pathogen Staphylococcus…”
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Purification of human plasma fibronectin using immobilized gelatin and Arg affinity chromatography
Published in Nature protocols (01-03-2008)“…This protocol describes a method for purification of fibronectin (Fn) from human plasma based on a combination of gel filtration and affinity chromatography…”
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