Search Results - "RINDER, Christine S"

Genetic Variants in P-Selectin and C-Reactive Protein Influence Susceptibility to Cognitive Decline After Cardiac Surgery by Mathew, Joseph P., MD, Podgoreanu, Mihai V., MD, Grocott, Hilary P., MD, White, William D., MPH, Morris, Richard W., PhD, Stafford-Smith, Mark, MD, Mackensen, G. Burkhard, MD, Rinder, Christine S., MD, Blumenthal, James A., PhD, Schwinn, Debra A., MD, Newman, Mark F., MD

“…Genetic Variants in P-Selectin and C-Reactive Protein Influence Susceptibility to Cognitive Decline After Cardiac Surgery Joseph P. Mathew, Mihai V…”
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Leukocyte Effects of C5a-Receptor Blockade During Simulated Extracorporeal Circulation by Rinder, Christine S., MD, Smith, Michael J., PhD, Rinder, Henry M., MD, Cortright, Daniel N., PhD, Brodbeck, Robbin M., PhD, Krause, James E., PhD, Smith, Brian R., MD

“…Background Distinct pathways of leukocyte activation during simulated cardiopulmonary bypass are mediated by the complement C5a anaphylatoxin. We hypothesized…”
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Monocyte Activation in On-Pump Versus Off-Pump Coronary Artery Bypass Surgery by Greilich, Philip E., MD, FAHA, Brouse, Chad F., MS, Rinder, Henry M., MD, Jessen, Michael E., MD, Rinder, Christine S., MD, Eberhart, Robert C., PhD, Whitten, Charles W., MD, Smith, Brian R., MD

“…Objective: Monocyte activation plays a key role in amplifying both inflammatory and coagulopathic sequelae in patients undergoing on-pump coronary artery…”
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Physiology of Hemostasis: With Relevance to Current and Future Laboratory Testing by Kriz, Nancy, BS, Rinder, Christine S., MD, Rinder, Henry M., MD

“…This article briefly details the physiologic and interdependent mechanisms of vascular hemostasis, with an eye toward how the laboratory can assist in…”
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Increased leukocyte-platelet adhesion in patients with graft occlusion after peripheral vascular surgery by Esposito, Claire J, Popescu, Wanda M, Rinder, Henry M, Schwartz, Jeffrey J, Smith, Brian R, Rinder, Christine S

“…Graft occlusion following peripheral vascular surgery is attributable to some combination of acute thrombosis, and progression of atherosclerosis: interactions…”
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Effects of ε-aminocaproic acid and aprotinin on leukocyte-platelet adhesion in patients undergoing cardiac surgery by GREILICH, Philip E, BROUSE, Chad F, RINDER, Christine S, SMITH, Brian R, SANDOVAL, Bernardo A, RINDER, Henry M, EBERHART, Robert C, JESSEN, Michael E

“…The administration of aprotinin during cardiopulmonary bypass (CPB) is hypothesized to decrease activation of leukocytes and platelets and possibly reduce…”
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Atrial Fibrillation After Cardiac Surgery/Cardiopulmonary Bypass Is Associated with Monocyte Activation by Fontes, Manuel L., Mathew, Joseph P., Rinder, Henry M., Zelterman, Daniel, Smith, Brian R., Rinder, Christine S.

“…Atrial fibrillation (AF) contributes significantly to morbidity and mortality in as many as one-third of patients after cardiac surgery that requires…”
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Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury by Rinder, Christine S, Fontes, Manuel, Mathew, Joseph P, Rinder, Henry M, Smith, Brian R

“…Renal injury remains a persistent complication of cardiopulmonary bypass (CPB) that, when sufficient to require dialysis, increases mortality eight-fold. The…”
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Reversibility of severe metabolic stress in stored platelets after in vitro plasma rescue or in vivo transfusion: restoration of secretory function and maintenance of platelet survival by Rinder, Henry M., Snyder, Edward L., Tracey, Jayne B., Dincecco, Dorothy, Wang, Chao, Baril, Laurence, Rinder, Christine S., Smith, Brian R.

“…BACKGROUND:  Determining reversible aspects of the platelet storage lesion may result in improved function and survival of transfused platelets. STUDY DESIGN…”
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Transcerebral Platelet Activation After Aortic Cross-Clamp Release is Linked to Neurocognitive Decline by Mathew, Joseph P., Rinder, Henry M., Smith, Brian R., Newman, Mark F., Rinder, Christine S.

“…Neurocognitive decline after cardiac surgery requiring cardiopulmonary bypass (CPB) may be caused in part by highly prothrombotic atheroemboli to the brain;…”
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Rofecoxib does not compromise platelet aggregation during anesthesia and surgery by SILVERMAN, David G, HALASZYNSKI, Thomas, SINATRA, Raymond, LUTHER, Martha, RINDER, Christine S

“…This study was undertaken because, although there is evidence that cyclooxygenase type 2 (COX)-2 inhibitors do not compromise platelets in healthy volunteers,…”
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Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation by Rinder, Christine S., Rinder, Henry M., Smith, Michael J., Fitch, Jane C.K., Tracey, Jayne B., Chandler, Wayne L., Rollins, Scott A., Smith, Brian R.

“…BACKGROUND:  Patients undergoing cardiac surgery requiring cardiopulmonary bypass develop a systemic inflammatory reaction. Antithrombin III (AT) has…”
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Platelet abnormalities associated with cerebral perfusion defects in cocaine dependence by Kosten, Thomas R, Tucker, Karen, Gottschalk, P.Christopher, Rinder, Christine S, Rinder, Henry M

“…This study assessed whether reduced regional cerebral blood flow (rCBF; hypoperfusion) in cocaine-dependent (CD) patients is associated with platelet…”
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The Effects of Heparin, Protamine, and Heparin/Protamine Reversal on Platelet Function Under Conditions of Arterial Shear Stress by Griffin, Michael J., Rinder, Henry M., Smith, Brian R., Tracey, Jayne B., Kriz, Nancy S., Li, Conan K., Rinder, Christine S.

“…Platelet dysfunction contributes to blood loss after cardiopulmonary bypass. This study examined the antiplatelet effects of heparin, protamine, and varying…”
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Role of C3 cleavage in monocyte activation during extracorporeal circulation by RINDER, C. S, RINDER, H. M, JOHNSON, K, SMITH, M, LEE, D. L, TRACEY, J, POLACK, G, HIGGINS, P, YEH, C. G, SMITH, B. R

“…We previously demonstrated that inhibiting formation of terminal complement components (C5a and C5b-9) prevents platelet and neutrophil (PMN) but not monocyte…”
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Platelet activation and aggregation during cardiopulmonary bypass by Rinder, C S, Bohnert, J, Rinder, H M, Mitchell, J, Ault, K, Hillman, R

“…Increases in plasma concentrations of platelet granule products such as platelet factor 4 and beta-thromboglobulin during cardiopulmonary bypass suggest that…”
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Aspirin or amiloride for cerebral perfusion defects in cocaine dependence by Kosten, Thomas R., Gottschalk, P.Christopher, Tucker, Karen, Rinder, Christine S., Dey, Holly M., Rinder, Henry M.

“…Cocaine dependent (CD) patients have regional cerebral blood flow (rCBF) deficits that may be related to occlusion of blood vessels by vasoconstriction and…”
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Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass by Rinder, Christine S., Gaal, Dorothy, Student, Laura A., Smith, Brian R.

“…Cardiopulmonary bypass has been shown in adults to activate platelets and leukocytes, lead to the formation of circulating platelet-leukocyte conjugates, and…”
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Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation by Rinder, Christine S., Rinder, Henry M., Smith, Michael J., Tracey, Jayne B., Fitch, Jane, Li, Lan, Rollins, Scott A., Smith, Brian R.

“…Objective: Complement activation is induced by cardiopulmonary bypass, and previous work found that late complement components (C5a, C5b-9) contribute to…”
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Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass by Mathew, Joseph P., Rinder, Christine S., Tracey, Jayne B., Auszura, Laura A., O'Connor, Theresa, Davis, Elizabeth, Smith, Brian R.

“…Granulocyte adhesion to ischemic tissue, mediated in large part by β 2 integrin receptors, is important in the pathophysiology of reperfusion injury…”
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