Search Results - "RIJZEWIJK, Luuk J"

Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus by Rijzewijk, Luuk J., MD, van der Meer, Rutger W., MD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Bax, Jeroen J., MD, PhD, Hammer, Sebastiaan, MSc, Romijn, Johannes A., MD, PhD, de Roos, Albert, MD, PhD, Lamb, Hildo J., MD, PhD

“…Objectives The purpose of this study was to compare myocardial triglyceride content and function between patients with uncomplicated type 2 diabetes mellitus…”
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Findings from Left Ventricular Strain and Strain Rate Imaging in Asymptomatic Patients With Type 2 Diabetes Mellitus by Ng, Arnold C.T., MBBS, Delgado, Victoria, MD, Bertini, Matteo, MD, van der Meer, Rutger W., MD, Rijzewijk, Luuk J., MD, Shanks, Miriam, MD, Nucifora, Gaetano, MD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Romijn, Johannes A., MD, PhD, de Roos, Albert, MD, PhD, Leung, Dominic Y., MBBS, PhD, Lamb, Hildo J., MD, PhD, Bax, Jeroen J., MD, PhD

“…Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy have not been well documented. LV multidirectional strain and…”
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Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies by Greulich, Sabrina, Chen, Weena J Y, Maxhera, Bujar, Rijzewijk, Luuk J, van der Meer, Rutger W, Jonker, Jacqueline T, Mueller, Heidi, de Wiza, Daniella Herzfeld, Floerke, Ralf-Ruediger, Smiris, Konstantinos, Lamb, Hildo J, de Roos, Albert, Bax, Jeroen J, Romijn, Johannes A, Smit, Jan W A, Akhyari, Payam, Lichtenberg, Artur, Eckel, Juergen, Diamant, Michaela, Ouwens, D Margriet

“…Adipokines are linked to the development of cardiovascular dysfunction in type 2 diabetes (DM2). In DM2-patients, circulating levels of omentin-1, an adipokine…”
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Right Ventricular Involvement in Diabetic Cardiomyopathy by WIDYA, Ralph L, VAN DER MEER, Rutger W, SMIT, Johannes W. A, RIJZEWIJK, Luuk J, DIAMANT, Michaela, BAX, Jeroen J, DE ROOS, Albert, LAMB, Hildo J

“…To compare magnetic resonance imaging-derived right ventricular (RV) dimensions and function between men with type 2 diabetes and healthy subjects, and to…”
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Effects of Hepatic Triglyceride Content on Myocardial Metabolism in Type 2 Diabetes by Rijzewijk, Luuk J., MD, Jonker, Jacqueline T., MD, van der Meer, Rutger W., MD, PhD, Lubberink, Mark, PhD, de Jong, Hugo W., PhD, Romijn, Johannes A., MD, PhD, Bax, Jeroen J., MD, PhD, de Roos, Albert, MD, PhD, Heine, Robert J., MD, PhD, Twisk, Jos W., MD, PhD, Windhorst, Albert D., PhD, Lammertsma, Adriaan A., PhD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Lamb, Hildo J., MD, PhD

“…Objectives The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in…”
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Short-Term Caloric Restriction Induces Accumulation of Myocardial Triglycerides and Decreases Left Ventricular Diastolic Function in Healthy Subjects by VAN DER MEER, Rutger W, HAMMER, Sebastiaan, SMIT, Johannes W. A, FRÖLICH, Marijke, BAX, Jeroen J, DIAMANT, Michaela, RIJZEWIJK, Luuk J, DE ROOS, Albert, ROMIJN, Johannes A, LAMB, Hildo J

“…Short-Term Caloric Restriction Induces Accumulation of Myocardial Triglycerides and Decreases Left Ventricular Diastolic Function in Healthy Subjects Rutger W…”
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Association of plasma osteoprotegerin and adiponectin with arterial function, cardiac function and metabolism in asymptomatic type 2 diabetic men by Chen, Weena J Y, Rijzewijk, Luuk J, van der Meer, Rutger W, Heymans, Martijn W, van Duinkerken, Eelco, Lubberink, Mark, Lammertsma, Adriaan A, Lamb, Hildo J, de Roos, Albert, Romijn, Johannes A, Smit, Jan W A, Bax, Jeroen J, Bjerre, Mette, Frystyk, Jan, Flyvbjerg, Allan, Diamant, Michaela

“…Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor receptor superfamily, is linked to cardiovascular disease. Negative associations exist…”
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Altered Myocardial Substrate Metabolism and Decreased Diastolic Function in Nonischemic Human Diabetic Cardiomyopathy: Studies With Cardiac Positron Emission Tomography and Magnetic Resonance Imaging by RIJZEWIJK, Luuk J, VAN DER MEER, Rutger W, LAMMERTSMA, Adriaan A, SMIT, Johannes W. A, DIAMANT, Michaela, LAMB, Hildo J, DE JONG, Hugo W. A. M, LUBBERINK, Mark, ROMIJN, Johannes A, BAX, Jeroen J, DE ROOS, Albert, TWISK, Jos W, HEINE, Robert J

“…This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated…”
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Myocardial Steatosis and Biventricular Strain and Strain Rate Imaging in Patients With Type 2 Diabetes Mellitus by NG, Arnold C. T, DELGADO, Victoria, DE ROOS, Albert, LEUNG, Dominic Y, LAMB, Hildo J, BAX, Jeroen J, BERTINI, Matteo, VAN DER MEER, Rutger W, RIJZEWIJK, Luuk J, SEE HOOI EWE, SIEBELINK, Hans-Marc, SMIT, Johannes W. A, DIAMANT, Michaela, ROMIJN, Johannes A

“…Magnetic resonance spectroscopy can quantify myocardial triglyceride content in type 2 diabetic patients. Its relation to alterations in left (LV) and right…”
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Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus by VAN DER MEER, Rutger W, RIJZEWIJK, Luuk J, HEINE, Robert J, LAMMERTSMA, Adriaan A, SMIT, Johannes W. A, DIAMANT, Michaela, DE JONG, Hugo W. A. M, LAMB, Hildo J, LUBBERINK, Mark, ROMIJN, Johannes A, BAX, Jeroen J, DE ROOS, Albert, KAMP, Otto, PAULUS, Walter J

“…Cardiac disease is the leading cause of mortality in type 2 diabetes mellitus (T2DM). Pioglitazone has been associated with improved cardiac outcome but also…”
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Circulating Long Noncoding RNAs in Personalized Medicine: Response to Pioglitazone Therapy in Type 2 Diabetes by de Gonzalo-Calvo, David, Kenneweg, Franziska, Bang, Claudia, Toro, Rocío, van der Meer, Rutger W., Rijzewijk, Luuk J., Smit, Johannes W.A., Lamb, Hildo J., Llorente-Cortes, Vicenta, Thum, Thomas

“…[...]assessment of lncRNA levels could constitute a major breakthrough in the development of personalized medicine to guide medical therapy, with important…”
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Altered Myocardial Substrate Metabolism and Decreased Diastolic Function in Nonischemic Human Diabetic Cardiomyopathy by Rijzewijk, Luuk J., MD, van der Meer, Rutger W., MD, PhD, Lamb, Hildo J., MD, PhD, de Jong, Hugo W.A.M., PhD, Lubberink, Mark, PhD, Romijn, Johannes A., MD, PhD, Bax, Jeroen J., MD, PhD, de Roos, Albert, MD, PhD, Twisk, Jos W., PhD, Heine, Robert J., MD, PhD, Lammertsma, Adriaan A., PhD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD

“…Objectives This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled,…”
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Effects of Short-Term High-Fat, High-Energy Diet on Hepatic and Myocardial Triglyceride Content in Healthy Men by van der Meer, Rutger W., Hammer, Sebastiaan, Lamb, Hildo J., Frölich, Marijke, Diamant, Michaela, Rijzewijk, Luuk J., de Roos, Albert, Romijn, Johannes A., Smit, Johannes W. A.

“…Context: An association has been suggested between elevated plasma nonesterified fatty acid (NEFA) levels, myocardial triglyceride (TG) accumulation, and…”
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The ageing male heart: myocardial triglyceride content as independent predictor of diastolic function by van der Meer, Rutger W., Rijzewijk, Luuk J., Diamant, Michaela, Hammer, Sebastiaan, Schär, Michael, Bax, Jeroen J., Smit, Johannes W.A., Romijn, Johannes A., de Roos, Albert, Lamb, Hildo J.

“…Aims In animal models of obesity and diabetes mellitus, myocardial TG accumulation is associated with decreased myocardial function. In the physiologically…”
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Circulating Long Noncoding RNAs in Personalized Medicine by de Gonzalo-Calvo, David, PhD, Kenneweg, Franziska, MSc, Bang, Claudia, PhD, Toro, Rocío, MD, PhD, van der Meer, Rutger W., MD, PhD, Rijzewijk, Luuk J., MD, Smit, Johannes W.A., MD, PhD, Lamb, Hildo J., MD, PhD, Llorente-Cortes, Vicenta, PhD, Thum, Thomas, MD, PhD

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Liver Fat Content in Type 2 Diabetes: Relationship With Hepatic Perfusion and Substrate Metabolism by RIJZEWIJK, Luuk J, VAN DER MEER, Rutger W, DIAMANT, Michaela, LUBBERINK, Mark, LAMB, Hildo J, ROMIJN, Johannes A, DE ROOS, Albert, TWISK, Jos W, HEINE, Robert J, LAMMERTSMA, Adriaan A, SMIT, Johannes W. A

“…Hepatic steatosis is common in type 2 diabetes. It is causally linked to the features of the metabolic syndrome, liver cirrhosis, and cardiovascular disease…”
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Activin A is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes by Chen, Weena J Y, Greulich, Sabrina, van der Meer, Rutger W, Rijzewijk, Luuk J, Lamb, Hildo J, de Roos, Albert, Smit, Johannes W A, Romijn, Johannes A, Ruige, Johannes B, Lammertsma, Adriaan A, Lubberink, Mark, Diamant, Michaela, Ouwens, D Margriet

“…Activin A released from epicardial adipose tissue has been linked to contractile dysfunction and insulin resistance in cardiomyocytes. This study investigated…”
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Pioglitazone Decreases Plasma Cholesteryl Ester Transfer Protein Mass, Associated With a Decrease in Hepatic Triglyceride Content, in Patients With Type 2 Diabetes by Jonker, Jacqueline T, Wang, Yanan, de Haan, Willeke, Diamant, Michaela, Rijzewijk, Luuk J, van der Meer, Rutger W, Lamb, Hildo J, Tamsma, Jouke T, de Roos, Albert, Romijn, Johannes A, Rensen, Patrick C.N, Smit, Johannes W.A

“…OBJECTIVE: Thiazolidinediones reduce hepatic steatosis and increase HDL cholesterol levels. In mice with human-like lipoprotein metabolism (APOE*3-Leiden.CETP…”
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Kinetic models for analysing myocardial [11C]palmitate data by de Jong, Hugo W. A. M., Rijzewijk, Luuk J., Lubberink, Mark, van der Meer, Rutger W., Lamb, Hildo J., Smit, Jan W. A., Diamant, Michaëla, Lammertsma, Adriaan A.

“…Purpose [ 11 C]Palmitate PET can be used to study myocardial fatty acid metabolism in vivo. Several models have been applied to describe and quantify its…”
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135 Influence of short-term excessive dietary fat intake on myocardial triglyceride content and function by vd Meer, Rutger, Hammer, Sebastiaan, Rijzewijk, Luuk J, Diamant, Michaela, Romijn, Johannes A, Smit, Johannes WA, De Roos, Albert, Lamb, Hildo J

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