Search Results - "RIGO, M"
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1
Development of porous spray-dried inhalable particles using an organic solvent-free technique
Published in Powder technology (15-01-2019)“…A simple technique to produce spray-dried porous particles for inhalatory administration was developed. The particles were produced using water as solvent,…”
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2
Modelling of the spray drying process for particle design
Published in Chemical engineering research & design (01-04-2018)“…[Display omitted] •A mathematical model for inhalable powder production in a spray dryer is developed.•Particle size and aerodynamic diameter are well…”
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3
Levofloxacin dry powder inhaler for high dose delivery
Published in Powder technology (02-01-2024)“…Mucous plugs in the respiratory system of cystic fibrosis patients are often infected, typically by Pseudomonas aeruginosa. Nebulized levofloxacin is effective…”
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4
Prediction of the particle size distribution of the aerosol generated by a pressurized metered-dose inhaler
Published in Powder technology (01-02-2022)“…Pressurized metered dose inhalers (pMDIs) are devices widely used for drug delivery in the respiratory tract. In this work, a mathematical model to predict the…”
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5
Influence of the valve on the performance of two cylindrical valved holding chambers
Published in Powder technology (15-01-2023)“…The use of valved holding chambers (VHCs) is recommended when pressurized metered dose inhalers (pMDI) are prescribed. These medical devices decrease…”
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6
Another generalization of abelian equivalence: Binomial complexity of infinite words
Published in Theoretical computer science (11-10-2015)“…The binomial coefficient of two words u and v is the number of times v occurs as a subsequence of u. Based on this classical notion, we introduce the…”
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Near-infrared spectroscopic applications in pharmaceutical particle technology
Published in Drug development and industrial pharmacy (03-10-2019)“…Near-infrared spectroscopy (NIRS) is nowadays an established analytical technique in the pharmaceutical industry. The aim of this review is to present the…”
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8
Aerosol deposition and emission from a United States Pharmacopeia‐induction port when using a pressurized metered‐dose inhaler with and without a valved holding chamber
Published in Canadian journal of chemical engineering (01-08-2024)“…The testing of pharmaceutical aerosols includes measuring the aerodynamic particle size distribution, which is usually performed on cascade impactors. In the…”
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9
Structure-based Methods for Binding Mode and Binding Affinity Prediction for Peptide-MHC Complexes
Published in Current topics in medicinal chemistry (01-01-2018)“…Understanding the mechanisms involved in the activation of an immune response is essential to many fields in human health, including vaccine development and…”
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ChaperISM: improved chaperone binding prediction using position-independent scoring matrices
Published in Bioinformatics (01-02-2020)“…Abstract Motivation Understanding the mechanisms of client protein interaction with Hsp70 chaperones is essential to analyze the complex dynamics in the…”
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Orphan Formulations in Pediatric Schistosomiasis Treatment: Development and Characterization of Praziquantel Nanoparticle—Loaded Powders for Reconstitution
Published in AAPS PharmSciTech (01-11-2019)“…Praziquantel is a broad spectrum antihelmintic agent and represents the drug of choice for the treatment of schistosomiasis. However, its low aqueous…”
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Nanoparticle-based chewable gels of praziquantel
Published in Pharmaceutical development and technology (02-01-2023)“…Chewable gels present significant advantages over conventional dosage forms, despite their development is not comprehensively assessed. In this sense, six…”
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13
Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy
Published in Frontiers in immunology (04-10-2017)“…Immunotherapy has become one of the most promising avenues for cancer treatment, making use of the patient's own immune system to eliminate cancer cells…”
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14
The anti‐epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA‐ and glycine‐gated currents
Published in British journal of pharmacology (01-07-2002)“…In this study in vitro and in vivo approaches were combined in order to investigate if the anti‐epileptic mechanism(s) of action of levetiracetam (LEV;…”
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Structural Modeling and Molecular Dynamics of the Immune Checkpoint Molecule HLA-G
Published in Frontiers in immunology (06-11-2020)“…HLA-G is considered to be an immune checkpoint molecule, a function that is closely linked to the structure and dynamics of the different HLA-G isoforms…”
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A multicenter LArge retrospectIve daTabase on the personalization of stereotactic ABlative radiotherapy use in lung metastases from colon-rectal cancer: The LaIT-SABR study
Published in Radiotherapy and oncology (01-01-2022)“…•SABR provides high rates of local control to lung oligometastases.•Local control of colorectal lung metastases seems lower compared to other tumors.•We…”
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Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks
Published in Glia (01-04-2011)“…Microglial cells invade the central nervous system during embryonic development, but their developmental functional roles in vivo remain largely unknown…”
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PepSim: T-cell cross-reactivity prediction via comparison of peptide sequence and peptide-HLA structure
Published in Frontiers in immunology (28-04-2023)“…Peptide-HLA class I (pHLA) complexes on the surface of tumor cells can be targeted by cytotoxic T-cells to eliminate tumors, and this is one of the bases for…”
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Variation of modulation and expression of biomarkers associated with inflammation in bariatric surgery patients: A systematic review and meta-analysis
Published in Surgery (01-11-2023)“…Bariatric surgery is an effective intervention that causes a series of metabolic changes related to inflammatory processes; however, the variation of…”
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Glycine receptors control the generation of projection neurons in the developing cerebral cortex
Published in Cell death and differentiation (01-11-2014)“…The development of the cerebral cortex requires coordinated regulation of proliferation, specification, migration and differentiation of cortical progenitors…”
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