Search Results - "RIGAULT DE LA LONGRAIS, Irene A"
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The circadian gene NPAS2 is a novel prognostic biomarker for breast cancer
Published in Breast cancer research and treatment (01-04-2010)“…Mounting evidence suggests that neuronal PAS domain protein 2 ( NPAS2 ) and other circadian genes are involved in tumorigenesis and tumor growth, possibly…”
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Hypermethylation of let-7a-3 in Epithelial Ovarian Cancer Is Associated with Low Insulin-like Growth Factor-II Expression and Favorable Prognosis
Published in Cancer research (Chicago, Ill.) (01-11-2007)“…MicroRNAs (miRNA) are endogenous noncoding small RNAs that regulate the activity of mRNAs. Many miRNA genes, including let-7a-3, are located in CpG islands,…”
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ERCC1 Genotype and Phenotype in Epithelial Ovarian Cancer Identify Patients Likely to Benefit From Paclitaxel Treatment in Addition to Platinum-Based Therapy
Published in Journal of clinical oncology (20-11-2007)“…To investigate the effect of excision repair cross-complementation group 1 (ERCC1) on treatment response and survival of patients treated with platinum…”
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Peptide concentrations and mRNA expression of IGF-I, IGF-II and IGFBP-3 in breast cancer and their associations with disease characteristics
Published in Breast cancer research and treatment (01-05-2009)“…Purpose To measure peptide concentrations and mRNA expression of the IGF Family in breast cancer and to examine their associations with the disease features…”
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Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II
Published in European Journal of Cancer (01-08-2009)“…Abstract Lin-28 and lin-28B are RNA-binding proteins which can block microRNA let-7 maturation and affect the differentiation and proliferation of embryonic…”
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Klotho Expression in Epithelial Ovarian Cancer and its Association with Insulin-Like Growth Factors and Disease Progression
Published in Cancer investigation (01-01-2008)“…Klotho is an anti-aging hormone and is able to suppress the action of IGFs. High IGF activities are associated with cancer risk and tumor progression. Klotho's…”
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IGF-I in epithelial ovarian cancer and its role in disease progression
Published in Growth factors (Chur, Switzerland) (01-10-2007)“…Insulin-like growth factor-I (IGF-I) is known to be involved in the development and progression of several types of solid tumors including ovarian cancer…”
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Aberrant promoter methylation of multiple genes in malignant ovarian tumors and in ovarian tumors with low malignant potential
Published in Cancer (15-07-2006)“…BACKGROUND. Methylation‐mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and…”
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The relationship of insulin-like growth factor-II, insulin-like growth factor binding protein-3, and estrogen receptor-alpha expression to disease progression in epithelial ovarian cancer
Published in Clinical cancer research (15-02-2006)“…PURPOSE: The insulin-like growth factor (IGF) system plays important roles in cancer; blocking IGF signaling has been shown to have therapeutic effects on…”
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Prognostic Value of the Human Kallikrein Gene 15 Expression in Ovarian Cancer
Published in Journal of clinical oncology (15-08-2003)“…KLK15 is a newly cloned human kallikrein gene. Many kallikreins were found to be differentially expressed in ovarian cancer. Like other kallikreins, KLK15 is…”
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Expression of MDR1 in epithelial ovarian cancer and its association with disease progression
Published in Oncology research (01-01-2007)“…The purposes of this study were to analyze MDR1 expression in ovarian tumors prior to chemotherapy, to correlate the expression with p16, IGFs, ERalpha, and…”
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Higher Human Kallikrein Gene 4 (KLK4) Expression Indicates Poor Prognosis of Ovarian Cancer Patients
Published in Clinical cancer research (01-08-2001)“…Purpose: Kallikrein gene 4 ( KLK4 , also known as prostase/ KLK-L1 ), located on chromosome 19q13.4, is one of the newly discovered members of the human KLK…”
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Prognostic Value of Human Kallikrein 10 Expression in Epithelial Ovarian Carcinoma
Published in Clinical cancer research (01-08-2001)“…Purpose: Human kallikrein 10 (hK10; also known as the normal epithelial cell-specific 1 gene and protein) is a secreted serine protease, which belongs to the…”
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Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma
Published in International journal of cancer (10-09-2003)“…Human kallikrein 11 (hK11/trypsin‐like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases…”
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The oncogene phosphatidylinositol 3'-kinase catalytic subunit alpha promotes angiogenesis via vascular endothelial growth factor in ovarian carcinoma
Published in Cancer research (Chicago, Ill.) (15-07-2003)“…The gene of phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) has been implicated as an oncogene in ovarian cancer [L. Shayesteh et al., Nat…”
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A Multiparametric Panel for Ovarian Cancer Diagnosis, Prognosis, and Response to Chemotherapy
Published in Clinical cancer research (01-12-2007)“…Purpose: Our goal was to examine a panel of 11 biochemical variables, measured in cytosolic extracts of ovarian tissues (normal, benign, and malignant) by…”
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