Search Results - "RIETSCH, Arne"

The Type III Secretion Translocation Pore Senses Host Cell Contact by Armentrout, Erin I, Rietsch, Arne

“…Type III secretion systems (T3SS) are nano-syringes used by a wide range of Gram-negative pathogens to promote infection by directly injecting effector…”
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"The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm" by Jensen, Jaime L, Yamini, Shavait, Rietsch, Arne, Spiller, Benjamin W

“…Type III protein secretion systems (T3SS) deliver effector proteins from the Gram-negative bacterial cytoplasm into a eukaryotic host cell through a…”
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NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity by Minns, Martin S., Liboro, Karl, Lima, Tatiane S., Abbondante, Serena, Miller, Brandon A., Marshall, Michaela E., Tran Chau, Jolynn, Roistacher, Alicia, Rietsch, Arne, Dubyak, George R., Pearlman, Eric

“…Macrophages infected with Gram-negative bacteria expressing Type III secretion system (T3SS) activate the NLRC4 inflammasome, resulting in Gasdermin D…”
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ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival by Sun, Yan, Karmakar, Mausita, Taylor, Patricia R, Rietsch, Arne, Pearlman, Eric

“…Pseudomonas aeruginosa is a leading cause of blinding corneal ulcers worldwide. To determine the role of type III secretion in the pathogenesis of P…”
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PopB-PcrV Interactions Are Essential for Pore Formation in the Pseudomonas aeruginosa Type III Secretion System Translocon by Kundracik, Emma, Trichka, Josephine, Díaz Aponte, José, Roistacher, Alicia, Rietsch, Arne

“…The type III secretion system (T3SS) is a syringe-like virulence factor that delivers bacterial proteins directly into the cytoplasm of host cells. An…”
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Control of type III secretion activity and substrate specificity by the cytoplasmic regulator PcrG by Lee, Pei-Chung, Zmina, Stephanie Elizabeth, Stopford, Charles Morgan, Toska, Jonida, Rietsch, Arne

“…Pathogenic Gram-negative bacteria use syringe-like type III secretion systems (T3SS) to inject effector proteins directly into targeted host cells. Effector…”
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ExsE, a Secreted Regulator of Type III Secretion Genes in Pseudomonas aeruginosa by Rietsch, Arne, Vallet-Gely, Isabelle, Dove, Simon L., Mekalanos, John J.

“…Type III secretion systems are toxin delivery systems that are present in a large number of pathogens. A hallmark of all type III secretion systems studied to…”
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TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways by Sun, Yan, Karmakar, Mausita, Roy, Sanhita, Ramadan, Raniyah T, Williams, Susan R, Howell, Scott, Shive, Carey L, Han, Yiping, Stopford, Charles M, Rietsch, Arne, Pearlman, Eric

“…Pseudomonas aeruginosa is a major cause of blindness and visual impairment in the United States and worldwide. Using a murine model of keratitis in which…”
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Host response and bacterial virulence factor expression in Pseudomonas aeruginosa and Streptococcus pneumoniae corneal ulcers by Karthikeyan, Rajapandian SivaGanesa, Priya, Jeganathan Lakshmi, Leal, Jr, Sixto M, Toska, Jonida, Rietsch, Arne, Prajna, Venkatesh, Pearlman, Eric, Lalitha, Prajna

“…P. aeruginosa and S. pneumoniae are major bacterial causes of corneal ulcers in industrialized and in developing countries. The current study examined host…”
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Metabolic regulation of type III secretion gene expression in Pseudomonas aeruginosa by Rietsch, Arne, Mekalanos, John J.

“…Summary Type III secretion‐mediated cytotoxicity is one of the key virulence mechanisms of the opportunistic pathogen Pseudomonas aeruginosa. Prior data from…”
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Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV by Lee, Pei-Chung, Stopford, Charles M, Svenson, Amanda G, Rietsch, Arne

“…Pseudomonas aeruginosa uses a type III secretion system to inject protein effectors into a targeted host cell. Effector secretion is triggered by host cell…”
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ExoS Controls the Cell Contact-Mediated Switch to Effector Secretion in Pseudomonas aeruginosa by Cisz, Michelle, Lee, Pei-Chung, Rietsch, Arne

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Role of the Type III Secreted Exoenzymes S, T, and Y in Systemic Spread of Pseudomonas aeruginosa PAO1 In Vivo by Vance, Russell E, Rietsch, Arne, Mekalanos, John J

“…Pseudomonas aeruginosa uses a dedicated type III secretion system to deliver toxins directly into the cytoplasm of host cells. While progress has been made in…”
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Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates by Toska, Jonida, Sun, Yan, Carbonell, Dalina Alvarez, Foster, Altreisha N-S, Jacobs, Michael R, Pearlman, Eric, Rietsch, Arne

“…Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion…”
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THE GENETICS OF DISULFIDE BOND METABOLISM by Rietsch, Arne, Beckwith, Jonathan

“…Disulfide bonds are required for the stability and function of a large number of proteins. Genetic analysis in combination with biochemical studies have…”
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Dimerization of the Pseudomonas aeruginosa Translocator Chaperone PcrH Is Required for Stability, Not Function by Tomalka, Amanda G, Zmina, Stephanie E, Stopford, Charles M, Rietsch, Arne

“…Type III secretion systems rely on hydrophobic translocator proteins that form a pore in the host cell membrane to deliver effector proteins into targeted host…”
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Effect of Metabolic Imbalance on Expression of Type III Secretion Genes in Pseudomonas aeruginosa by RIETSCH, Arne, WOLFGANG, Matthew C, MEKALANOS, John J

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An in vivo Pathway for Disulfide Bond Isomerization in Escherichia coli by Rietsch, Arne, Belin, Dominique, Martin, Nancy, Beckwith, Jonathan

“…Biochemical studies have shown that the periplasmic protein disulfide oxidoreductase DsbC can isomerize aberrant disulfide bonds. Here we present the first…”
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Isolation and Characterization of a Generalized Transducing Phage for Pseudomonas aeruginosa Strains PAO1 and PA14 by BUDZIK, Jonathan M, ROSCHE, William A, RIETSCH, Arne, O'TOOLE, George A

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Pseudomonas aeruginosa Effector ExoS Inhibits ROS Production in Human Neutrophils by Vareechon, Chairut, Zmina, Stephanie Elizabeth, Karmakar, Mausita, Pearlman, Eric, Rietsch, Arne

“…Neutrophils are the first line of defense against bacterial infections, and the generation of reactive oxygen species is a key part of their arsenal. Pathogens…”
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