Search Results - "RIEMENSCHNEIDER, Markus J"

Histological classification and molecular genetics of meningiomas by Riemenschneider, Markus J, Perry, Arie, Reifenberger, Guido

“…Meningiomas account for up to 30% of all primary intracranial tumours. They are histologically classified according to the World Health Organization (WHO)…”
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Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion by Alieva, Maria, Leidgens, Verena, Riemenschneider, Markus J., Klein, Christoph A., Hau, Peter, van Rheenen, Jacco

“…The pathogenesis of glioblastoma (GBM) is characterized by highly invasive behavior allowing dissemination and progression. A conclusive image of the invasive…”
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Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients by Schlottau, Kore, Forth, Leonie, Angstwurm, Klemens, Höper, Dirk, Zecher, Daniel, Liesche, Friederike, Hoffmann, Bernd, Kegel, Victoria, Seehofer, Daniel, Platen, Sabine, Salzberger, Bernd, Liebert, Uwe G, Niller, Hans-Helmut, Schmidt, Barbara, Matiasek, Kaspar, Riemenschneider, Markus J, Brochhausen, Christoph, Banas, Bernhard, Renders, Lutz, Moog, Philipp, Wunderlich, Silke, Seifert, Christian L, Barreiros, Ana, Rahmel, Axel, Weiss, Jutta, Tappe, Dennis, Herden, Christiane, Schmidt-Chanasit, Jonas, Schwemmle, Martin, Rubbenstroth, Dennis, Schlegel, Jürgen, Pietsch, Corinna, Hoffmann, Donata, Jantsch, Jonathan, Beer, Martin

“…Evidence of Borna disease virus 1 infection in humans is limited; in this report, donor-derived Borna virus encephalitis is shown to occur in three solid-organ…”
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Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs by Schulze, Markus, Sommer, Annika, Plötz, Sonja, Farrell, Michaela, Winner, Beate, Grosch, Janina, Winkler, Jürgen, Riemenschneider, Markus J

“…Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson's disease (PD) have allowed insights into the mechanisms of…”
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The neuropathology of fatal encephalomyelitis in human Borna virus infection by Liesche, Friederike, Ruf, Viktoria, Zoubaa, Saida, Kaletka, Gwendolyn, Rosati, Marco, Rubbenstroth, Dennis, Herden, Christiane, Goehring, Lutz, Wunderlich, Silke, Wachter, Miguel Frederic, Rieder, Georg, Lichtmannegger, Ines, Permanetter, Willibald, Heckmann, Josef G., Angstwurm, Klemens, Neumann, Bernhard, Märkl, Bruno, Haschka, Stefan, Niller, Hans-Helmut, Schmidt, Barbara, Jantsch, Jonathan, Brochhausen, Christoph, Schlottau, Kore, Ebinger, Arnt, Hemmer, Bernhard, Riemenschneider, Markus J., Herms, Jochen, Beer, Martin, Matiasek, Kaspar, Schlegel, Jürgen

“…After many years of controversy, there is now recent and solid evidence that classical Borna disease virus 1 (BoDV-1) can infect humans. On the basis of six…”
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Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration by Ramesh, Vidya, Bayam, Efil, Cernilogar, Filippo M, Bonapace, Ian M, Schulze, Markus, Riemenschneider, Markus J, Schotta, Gunnar, Götz, Magdalena

“…In order to understand whether early epigenetic mechanisms instruct the long-term behavior of neural stem cells (NSCs) and their progeny, we examined Uhrf1…”
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The Role of Translocator Protein TSPO in Hallmarks of Glioblastoma by Ammer, Laura-Marie, Vollmann-Zwerenz, Arabel, Ruf, Viktoria, Wetzel, Christian H., Riemenschneider, Markus J., Albert, Nathalie L., Beckhove, Philipp, Hau, Peter

“…Glioblastoma (GBM) is the most fatal primary brain cancer in adults. Despite extensive treatment, tumors inevitably recur, leading to an average survival time…”
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PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia by Blazquez, Raquel, Wlochowitz, Darius, Wolff, Alexander, Seitz, Stefanie, Wachter, Astrid, Perera‐Bel, Julia, Bleckmann, Annalen, Beißbarth, Tim, Salinas, Gabriela, Riemenschneider, Markus J., Proescholdt, Martin, Evert, Matthias, Utpatel, Kirsten, Siam, Laila, Schatlo, Bawarjan, Balkenhol, Marko, Stadelmann, Christine, Schildhaus, Hans‐Ulrich, Korf, Ulrike, Reinz, Eileen, Wiemann, Stefan, Vollmer, Elena, Schulz, Mathias, Ritter, Uwe, Hanisch, Uwe K., Pukrop, Tobias

“…Mutations and activation of the PI3K signaling pathway in breast cancer cells have been linked to brain metastases. However, here we describe that in some…”
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Use of statins or NSAIDs and survival of patients with high-grade glioma by Seliger, Corinna, Schaertl, Julia, Gerken, Michael, Luber, Christian, Proescholdt, Martin, Riemenschneider, Markus J, Leitzmann, Michael F, Hau, Peter, Klinkhammer-Schalke, Monika

“…High-grade glioma (HGG) is associated with a limited prognosis. Drug repurposing has become of increasing interest to improve standard therapy. Statins and…”
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Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation by Leidgens, Verena, Proske, Judith, Rauer, Lisa, Moeckel, Sylvia, Renner, Kathrin, Bogdahn, Ulrich, Riemenschneider, Markus J, Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna

“…Glioblastoma (GBM) is the most common and malignant type of primary brain tumor and associated with a devastating prognosis. Signal transducer and activator of…”
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Mitochondrial and Cellular Function in Fibroblasts, Induced Neurons, and Astrocytes Derived from Case Study Patients: Insights into Major Depression as a Mitochondria-Associated Disease by Cardon, Iseline, Grobecker, Sonja, Kücükoktay, Selin, Bader, Stefanie, Jahner, Tatjana, Nothdurfter, Caroline, Koschitzki, Kevin, Berneburg, Mark, Weber, Bernhard H F, Stöhr, Heidi, Höring, Marcus, Liebisch, Gerhard, Braun, Frank, Rothammer-Hampl, Tanja, Riemenschneider, Markus J, Rupprecht, Rainer, Milenkovic, Vladimir M, Wetzel, Christian H

“…The link between mitochondria and major depressive disorder (MDD) is increasingly evident, underscored both by mitochondria's involvement in many mechanisms…”
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Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems by Schuster, Martina, Braun, Frank K, Chiang, Dapi Meng-Lin, Ludwig, Christina, Meng, Chen, Grätz, Christian, Kirchner, Benedikt, Proescholdt, Martin, Hau, Peter, Steinlein, Ortrud K, Pfaffl, Michael W, Riemenschneider, Markus J, Reithmair, Marlene

“…Newer 3D culturing approaches are a promising way to better mimic the tumor microenvironment and to study the interactions between the heterogeneous cell…”
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Metabolic Heterogeneity of Brain Tumor Cells of Proneural and Mesenchymal Origin by Seliger, Corinna, Meyer, Anne-Louise, Leidgens, Verena, Rauer, Lisa, Moeckel, Sylvia, Jachnik, Birgit, Proske, Judith, Dettmer, Katja, Rothhammer-Hampl, Tanja, Kaulen, Leon D., Riemenschneider, Markus J., Oefner, Peter J., Kreutz, Marina, Schmidt, Nils-Ole, Merrill, Marsha, Uhl, Martin, Renner, Kathrin, Vollmann-Zwerenz, Arabel, Proescholdt, Martin, Hau, Peter

“…Brain-tumor-initiating cells (BTICs) of proneural and mesenchymal origin contribute to the highly malignant phenotype of glioblastoma (GB) and resistance to…”
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SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation by Lindemann, Carina, Hackmann, Oliver, Delic, Sabit, Schmidt, Natalie, Reifenberger, Guido, Riemenschneider, Markus J.

“…The suppressor of cytokine signaling 3 ( SOCS3 ) gene is one of eight structurally related genes of the SOCS family and has been suggested to function as a…”
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Heterogeneity of Amino Acid Profiles of Proneural and Mesenchymal Brain-Tumor Initiating Cells by Seliger, Corinna, Rauer, Lisa, Wüster, Anne-Louise, Moeckel, Sylvia, Leidgens, Verena, Jachnik, Birgit, Ammer, Laura-Marie, Heckscher, Simon, Dettmer, Katja, Riemenschneider, Markus J, Oefner, Peter J, Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter

“…Glioblastomas are highly malignant brain tumors that derive from brain-tumor-initiating cells (BTICs) and can be subdivided into several molecular subtypes…”
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Epidermal Growth Factor Receptor Mutations and Gene Amplification in Non–Small-Cell Lung Cancer: Molecular Analysis of the IDEAL/INTACT Gefitinib Trials by BELL, Daphne W, LYNCH, Thomas J, KREBS, Annetta D, JOHNSON, David H, GIACCONE, Gmseppe, HERBST, Roy S, MANEGOLD, Christian, FUKUOKA, Masahiro, KRIS, Mark G, BASELGA, José, OCHS, Judith S, HABER, Daniel A, HASERLAT, Sara M, HARRIS, Patricia L, OKIMOTO, Ross A, BRANNIGAN, Brian W, SGROI, Dennis C, MUIR, Beth, RIEMENSCHNEIDER, Markus J, IACONA, Renee Bailey

“…Most cases of non-small-cell lung cancer (NSCLC) with dramatic responses to gefitinib have specific activating mutations in the epidermal growth factor…”
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Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma by Gerthofer, Valeria, Kreutz, Marina, Renner, Kathrin, Jachnik, Birgit, Dettmer, Katja, Oefner, Peter, Riemenschneider, Markus J, Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna

“…Glioblastoma remains a fatal diagnosis. Previous research has shown that metformin, which is an inhibitor of complex I of the respiratory chain, may inhibit…”
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Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany by Bauswein, Markus, Eidenschink, Lisa, Knoll, Gertrud, Neumann, Bernhard, Angstwurm, Klemens, Zoubaa, Saida, Riemenschneider, Markus J, Lampl, Benedikt M J, Pregler, Matthias, Niller, Hans Helmut, Jantsch, Jonathan, Gessner, André, Eberhardt, Yvonne, Huppertz, Gunnar, Schramm, Torsten, Kühn, Stefanie, Koller, Michael, Drasch, Thomas, Ehrl, Yvonne, Banas, Bernhard, Offner, Robert, Schmidt, Barbara, Banas, Miriam C

“…More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region…”
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Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease by Zatcepin, Artem, Gnörich, Johannes, Rauchmann, Boris-Stephan, Bartos, Laura M, Wagner, Stephan, Franzmeier, Nicolai, Malpetti, Maura, Xiang, Xianyuan, Shi, Yuan, Parhizkar, Samira, Grosch, Maximilian, Wind-Mark, Karin, Kunte, Sebastian T, Beyer, Leonie, Meyer, Carolin, Brösamle, Desirée, Wendeln, Ann-Christin, Osei-Sarpong, Collins, Heindl, Steffanie, Liesz, Arthur, Stoecklein, Sophia, Biechele, Gloria, Finze, Anika, Eckenweber, Florian, Lindner, Simon, Rominger, Axel, Bartenstein, Peter, Willem, Michael, Tahirovic, Sabina, Herms, Jochen, Buerger, Katharina, Simons, Mikael, Haass, Christian, Rupprecht, Rainer, Riemenschneider, Markus J, Albert, Nathalie L, Beyer, Marc, Neher, Jonas J, Paeger, Lars, Levin, Johannes, Höglinger, Günter U, Perneczky, Robert, Ziegler, Sibylle I, Brendel, Matthias

“…Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is…”
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Health-Related Quality of Life and Treatment Satisfaction of Patients with Malignant IDH Wild-Type Gliomas and Their Caregivers by Fischl, Anna, Gerken, Michael, Lindberg-Scharf, Patricia, Haedenkamp, Tareq M, Rosengarth, Katharina, Hillberg, Andrea, Vogelhuber, Martin, Schön, Ingrid, Proescholdt, Martin, Araceli, Tommaso, Koller, Michael, Herrmann, Anne, Kölbl, Oliver, Pukrop, Tobias, Riemenschneider, Markus J, Schmidt, Nils Ole, Klinkhammer-Schalke, Monika, Linker, Ralf, Hau, Peter, Bumes, Elisabeth

“…(1) Background: Clinical aspects like sex, age, Karnofsky Performance Scale (KPS) and psychosocial distress can affect the health-related quality of life…”
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