Search Results - "RIEKER, Ralf J"

Vascular occlusion by neutrophil extracellular traps in COVID-19 by Leppkes, Moritz, Knopf, Jasmin, Naschberger, Elisabeth, Lindemann, Aylin, Singh, Jeeshan, Herrmann, Irmgard, Stürzl, Michael, Staats, Léonie, Mahajan, Aparna, Schauer, Christine, Kremer, Anita N., Völkl, Simon, Amann, Kerstin, Evert, Katja, Falkeis, Christina, Wehrfritz, Andreas, Rieker, Ralf J., Hartmann, Arndt, Kremer, Andreas E., Neurath, Markus F., Muñoz, Luis E., Schett, Georg, Herrmann, Martin

“…Coronavirus induced disease 2019 (COVID-19) can be complicated by severe organ damage leading to dysfunction of the lungs and other organs. The processes that…”
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SMARCA4 and SMARCA2 Deficiency in Non-small Cell Lung Cancer: Immunohistochemical Survey of 316 Consecutive Specimens by Herpel, Esther, MD, Rieker, Ralf J., MD, Dienemann, Hendrik, MD, Muley, Thomas, PhD, Meister, Michael, PhD, Hartmann, Arndt, MD, Warth, Arne, MD, Agaimy, Abbas, MD

“…Abstract The chromatin remodeling Switch Sucrose Non-Fermentable (SWI/SNF) complex has been increasingly implicated in the pathogenesis and dedifferentiation…”
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Contribution of serum lipids and cholesterol cellular metabolism in lung cancer development and progression by Hartmann, Philipp, Trufa, Denis I., Hohenberger, Katja, Tausche, Patrick, Trump, Sonja, Mittler, Susanne, Geppert, Carol I., Rieker, Ralf J., Schieweck, Oliver, Sirbu, Horia, Hartmann, Arndt, Finotto, Susetta

“…Neoplasms of the lungs are the leading cause of cancer incidence and mortality worldwide. Although immunotherapy has increased the overall survival of patients…”
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Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma by Kachler, Katerina, Bailer, Maximilian, Heim, Lisanne, Schumacher, Fabian, Reichel, Martin, Holzinger, Corinna D, Trump, Sonja, Mittler, Susanne, Monti, Juliana, Trufa, Denis I, Rieker, Ralf J, Hartmann, Arndt, Sirbu, Horia, Kleuser, Burkhard, Kornhuber, Johannes, Finotto, Susetta

“…The lipid hydrolase enzyme acid sphingomyelinase (ASM) is required for the conversion of the lipid cell membrane component sphingomyelin into ceramide. In…”
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IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer by Heim, Lisanne, Yang, Zuqin, Tausche, Patrick, Hohenberger, Katja, Chiriac, Mircea T, Koelle, Julia, Geppert, Carol-Immanuel, Kachler, Katerina, Miksch, Sarah, Graser, Anna, Friedrich, Juliane, Kharwadkar, Rakshin, Rieker, Ralf J, Trufa, Denis I, Sirbu, Horia, Neurath, Markus F, Kaplan, Mark H, Finotto, Susetta

“…Although lung cancer is the leading cause of cancer deaths worldwide, the mechanisms how lung cancer cells evade the immune system remain incompletely…”
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A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19 by Singh, Jeeshan, Herrmann, Irmgard, Mahajan, Aparna, Schauer, Christine, Shan, Xiaomei, Hartmann, Arndt, Rieker, Ralf J, Evert, Katja, Falkeis, Christina, Naschberger, Elisabeth, von Stillfried, Saskia, Boor, Peter, Muñoz, Luis E, Schett, Georg, Herrmann, Martin, Knopf, Jasmin

“…Vascular occlusions in patients with coronavirus diseases 2019 (COVID-19) have been frequently reported in severe outcomes mainly due to a dysregulation of…”
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Neutrophil extracellular traps characterize caseating granulomas by Zlatar, Leticija, Knopf, Jasmin, Singh, Jeeshan, Wang, Han, Muñoz-Becerra, Marco, Herrmann, Irmgard, Chukwuanukwu, Rebecca C., Eckstein, Markus, Eichhorn, Philip, Rieker, Ralf J., Naschberger, Elisabeth, Burkovski, Andreas, Krenn, Veit, Bilyy, Rostyslav, Butova, Tetiana, Liskina, Iryna, Kalabukha, Ihor, Khmel, Oleg, Boettcher, Michael, Schett, Georg, Butov, Dmytro, Tkachenko, Anton, Herrmann, Martin

“…Tuberculosis (TB) remains one of the top 10 causes of death worldwide and still poses a serious challenge to public health. Recent attention to neutrophils has…”
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Glucose-Restricted Diet Regulates the Tumor Immune Microenvironment and Prevents Tumor Growth in Lung Adenocarcinoma by Gähler, Alexander, Trufa, Denis I, Chiriac, Mircea T, Tausche, Patrick, Hohenberger, Katja, Brunst, Ann-Kathrin, Rauh, Manfred, Geppert, Carol I, Rieker, Ralf J, Krammer, Susanne, Leberle, Anna, Neurath, Markus F, Sirbu, Horia, Hartmann, Arndt, Finotto, Susetta

“…Lung cancer is the second common cancer type in western countries and has a high mortality. During the development and progression of the tumor, the nutrients…”
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Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma by Schenzel, Alicia, Geiger, Adriana, Nendel, Elvedina, Yang, Zuqin, Krammer, Susanne, Leberle, Anna, Brunst, Ann-Kathrin, Trump, Sonja, Mittler, Susanne, Rauh, Manfred, Geppert, Carol I, Tausche, Patrick, Hohenberger, Katja, Rieker, Ralf J, Schieweck, Oliver, Zundler, Sebastian, Finotto, Susetta

“…Allergic Asthma is a disease presenting various endotypes and no current therapies act curative but alleviate disease symptoms. Dietary interventions are…”
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Targeted deletion of Interleukin-3 results in asthma exacerbations by Kölle, Julia, Zimmermann, Theodor, Kiefer, Alexander, Rieker, Ralf J., Xepapadaki, Paraskevi, Zundler, Sebastian, Papadopoulos, Nikolaos G., Finotto, Susetta

“…The cytokine interleukin-3 (IL-3) acts on early hematopoietic precursor cells. In humans, Treg cells secrete IL-3 and repress inflammatory cells except for…”
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Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells by Grund, Janina C., Krammer, Susanne, Yang, Zuqin, Mitländer, Hannah, Rauh, Manfred, Zirlik, Sabine, Kiefer, Alexander, Zimmermann, Theodor, Rieker, Ralf J., Geppert, Carol I., Papadopoulos, Nikolaos G., Finotto, Susetta

“…Vitamin D3 (VitD3) is known to have immunomodulatory functions, and VitD3 deficiency is associated with more severe asthma. We aimed to assess the…”
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Genomic profiling reveals subsets of dedifferentiated liposarcoma to follow separate molecular pathways by Rieker, Ralf J., Weitz, Juergen, Lehner, Burkhard, Egerer, Gerlinde, Mueller, Andrea, Kasper, Bernd, Schirmacher, Peter, Joos, Stefan, Mechtersheimer, Gunhild

“…With the aim to provide more insight into their biology, a series of 79 liposarcomas (LS) representative of all main subtypes was analysed for chromosomal…”
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Reproducibility of immunohistochemical scoring for epidermal growth factor receptor expression in non-small cell lung cancer: round robin test by Rüschoff, Josef, Kerr, Keith M, Grote, Hans J, Middel, Peter, von Heydebreck, Anja, Alves, Venâncio A, Baldus, Stephan E, Büttner, Reinhard, Carvalho, Lina, Fink, Ludger, Jochum, Wolfram, Lo, Anthony W I, López-Ríos, Fernando, Marx, Alexander, Molina, Thierry J, Olszewski, Włodzimierz T, Rieker, Ralf J, Volante, Marco, Thunnissen, Erik, Wrba, Fritz, Celik, Ilhan, Störkel, Stephan

“…The addition of cetuximab to first-line chemotherapy substantially prolonged survival in patients with advanced non-small cell lung cancer whose tumors…”
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Mutation status of the mediator complex subunit 12 (MED12) in uterine leiomyomas and concurrent/metachronous multifocal peritoneal smooth muscle nodules (leiomyomatosis peritonealis disseminata) by Rieker, Ralf J., Agaimy, Abbas, Moskalev, Evgeny A., Hebele, Simone, Hein, Alexander, Mehlhorn, Grit, Beckmann, Matthias W., Hartmann, Arndt, Haller, Florian

“…The pathogenesis and classification of multicentric smooth muscle tumours with benign appearance and concurrent/metachronous uterine and peritoneal involvement…”
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Histologic classification of thymic epithelial tumors: Comparison of established classification schemes by Rieker, Ralf J., Hoegel, Josef, Morresi‐Hauf, Alicia, Hofmann, Walter J., Blaeker, Hendrik, Penzel, Roland, Otto, Herwart F.

“…The object of our multicenter retrospective study was to compare the new histologic World Health Organization (WHO) classification and the classical histologic…”
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Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma by Ehemann, Volker, Kern, Michael A., Breinig, Marco, Schnabel, Philipp A., Gunawan, Bastian, Schulten, Hans‐Jörg, Schlaeger, Christoph, Radlwimmer, Bernhard, Steger, Christina M., Dienemann, Hendrik, Lichter, Peter, Schirmacher, Peter, Rieker, Ralf J.

“…Thymomas and thymic carcinomas are peculiar epithelial tumors of the anterior mediastinum. They may show aggressive clinical behavior and are a paradigm for…”
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Thymolipoma. A report of nine cases, with emphasis on its association with myasthenia gravis by Rieker, Ralf J., Schirmacher, Peter, Schnabel, Philipp A., Moser, Katharina, Hoffmann, Hans, Dienemann, Hendrik, Pfannschmidt, Joachim

“…Purpose Thymolipomas are rare tumors of the anterior mediastinum accounting for up to 9% of all thymic tumors. These tumors are associated with autoimmune…”
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NFATc1 Promotes Antitumoral Effector Functions and Memory CD8 + T-cell Differentiation during Non-Small Cell Lung Cancer Development by Heim, Lisanne, Friedrich, Juliane, Engelhardt, Marina, Trufa, Denis I, Geppert, Carol I, Rieker, Ralf J, Sirbu, Horia, Finotto, Susetta

“…Nuclear factor of activated T cells 1 (NFATc1) is a transcription factor activated by T-cell receptor (TCR) and Ca signaling that affects T-cell activation and…”
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Chromosomal imbalances in carcinoma showing thymus-like elements (CASTLE) by Veits, Lothar, Mechtersheimer, Gunhild, Steger, Christina, Freitag, Jens, Mikuz, Gregor, Schmid, Kurt W., Hofmann, Walter, Schirmacher, Peter, Hartmann, Arndt, Rieker, Ralf J.

“…Carcinoma showing thymus-like elements (CASTLE) is a rare neoplasm of the thyroid gland resembling lymphoepithelioma-like and squamous cell carcinoma of the…”
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PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis by Ganzleben, Ingo, He, Gui-Wei, Günther, Claudia, Prigge, Elena-Sophie, Richter, Karsten, Rieker, Ralf J., Mougiakakos, Dimitrios, Neurath, Markus F., Becker, Christoph

“…Rationale Mitochondrial homeostasis has recently emerged as a focal point in the pathophysiology of idiopathic pulmonary fibrosis (IPF), but conflicting data…”
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