Search Results - "RIDER, M. H"

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B by Johanns, M., Lai, Y.-C., Hsu, M.-F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M, Rider, M H

“…Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated…”
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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia by Marsin, A-S., Bertrand†, L., Rider, M.H., Deprez, J., Beauloye, C., Vincent‡, M.F., Van den Berghe‡, G., Carling, D., Hue, L.

“…Background: The role of protein phosphorylation in the Pasteur effect—the phenomenon whereby anaerobic conditions stimulate glycolysis—has not been addressed…”
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Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase by DELPIERRE, Ghislain, RIDER, Mark H, COLLARD, Francois, STROOBANT, Vincent, VANSTAPEL, Florent, SANTOS, Helena, VAN SCHAFTINGEN, Emile

“…Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase. G Delpierre , M H Rider , F Collard , V Stroobant , F Vanstapel , H…”
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6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells by Ros, S, Flöter, J, Kaymak, I, Da Costa, C, Houddane, A, Dubuis, S, Griffiths, B, Mitter, R, Walz, S, Blake, S, Behrens, A, Brindle, K M, Zamboni, N, Rider, M H, Schulze, A

“…The bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 (PFKFB4) controls metabolic flux through allosteric regulation of glycolysis…”
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Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase by Johanns, M., Pyr dit Ruys, S., Houddane, A., Vertommen, D., Herinckx, G., Hue, L., Proud, C.G., Rider, M.H.

“…Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a key regulator of protein synthesis in mammalian cells. It phosphorylates and inhibits eEF2, the…”
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Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues by Hue, L, Rider, M H

“…Since Fru-2,6-P sub(2) is present in all mammalian tissues, it is tempting to suppose that it plays the major role in the control of glycolysis. The purpose of…”
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New targets of AMP-activated protein kinase by Hue, L, Beauloye, C, Bertrand, L, Horman, S, Krause, U, Marsin, A-S, Meisse, D, Vertommen, D, Rider, M H

“…The discovery of the AMP-activated protein kinase (AMPK) more than a decade ago has shed much light on the cellular response to stresses characterized by a…”
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Regulation of oxidative enzyme activity and eukaryotic elongation factor 2 in human skeletal muscle: influence of gender and exercise by Roepstorff, C., Schjerling, P., Vistisen, B., Madsen, M., Steffensen, C. H., Rider, M. H., Kiens, B.

“…Aim:  To investigate gender‐related differences in the responses of oxidative enzymes and eukaryotic elongation factor‐2 (eEF2) to exercise. Methods:  The…”
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Identification of Phosphorylation Sites on Human Deoxycytidine Kinase After Overexpression in Eucaryotic Cells by Smal, C., Vertommen, D., Bertrand, L., Rider, M. H., Van Den Neste, E., Bontemps, F.

“…Compelling evidence suggests that deoxycytidine kinase (dCK), a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant…”
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Role of fructose 2,6-bisphosphate in the control of heart glycolysis by DEPRE, C, RIDER, M. H, VEITCH, K, HUE, L

“…The aim of this work was to study whether changes in fructose 2,6-bisphosphate concentration are correlated with variations of the glycolytic flux in the…”
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Myocardial Ischemia and Increased Heart Work Modulate the Phosphorylation State of Eukaryotic Elongation Factor-2 by Horman, Sandrine, Beauloye, Christophe, Vertommen, Didier, Vanoverschelde, Jean-Louis, Hue, Louis, Rider, Mark H.

“…Protein synthesis, in particular peptide chain elongation, is an energy-consuming biosynthetic process. AMP-activated protein kinase (AMPK) is a key regulatory…”
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Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades by Deprez, Johan, Vertommen, Didier, Alessi, Dario R., Hue, Louis, Rider, Mark H.

“…To understand the insulin-induced activation of 6-phosphofructo-2-kinase (PFK-2) of the bifunctional enzyme PFK-2/fructose-2,6-bisphosphatase in heart, the…”
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Inhibition of Spliceosome Assembly by the Cell Cycle-regulated Protein Kinase MELK and Involvement of Splicing Factor NIPP1 by Vulsteke, Veerle, Beullens, Monique, Boudrez, An, Keppens, Stefaan, Van Eynde, Aleyde, Rider, Mark H., Stalmans, Willy, Bollen, Mathieu

“…NIPP1 is a ubiquitous nuclear protein that is required for spliceosome assembly. We report here that the phosphothreonine-binding Forkhead-associated domain of…”
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Palmitate inhibits liver glycolysis. Involvement of fructose 2,6-bisphosphate in the glucose/fatty acid cycle by Hue, L, Maisin, L, Rider, M H

“…In hepatocytes from overnight-fasted rats incubated with glucose, palmitate decreased the production of lactate, the detritiation of [2-3H]- and…”
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Site-directed mutagenesis of rat muscle 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase : role of Asp-130 in the 2-kinase domain by RIDER, M. H, CREPIN, K. M, DE CLOEDT, M, BERTRAND, L, HUE, L

“…Asp-130 of the recombinant skeletal-muscle 6-phosphofructo-2-kinase (PFK-2)/fructose-2,6-bisphosphatase was mutated into Ala in order to study its role in…”
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Complete nucleotide sequence coding for rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase derived from a cDNA clone by Darville, M.I., Crepin, K.M., Vandekerckhove, J., Van Damme, J., Octave, J.N., Rider, M.H., Marchand, M.J., Hue, L., Rousseau, G.G.

“…cDNA clones for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase were isolated from rat liver expression libraries in λgt11 by antibody, oligonucleotide,…”
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Molecular forms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase expressed in rat skeletal muscle by Crepin, K.M., De Cloedt, M, Vertommen, D, Foret, D, Michel, A, Rider, M.H., Rousseau, G.G., Hue, L

“…The rat cDNA for the muscle-type (M) isozyme of 6-phosphofructo-2-kinase (PFK-2)/fructose-2,6-bisphosphatase (FBPase-2) contains two putative translation…”
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Rat muscle 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Study of the kinase domain by site-directed mutagenesis by CREPIN, K. M, VERTOMMEN, D, DOM, G, HUE, L, RIDER, M. H

“…Sequence alignment and modeling of the 2-kinase domain of the liver bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, on…”
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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from frog skeletal muscle : purification, kinetics and immunological properties by PYKO, M, RIDER, M. H, WEGENER, G

“…Fructose 2,6-bisphosphate is the most potent activator of 6-phosphofructo-1-kinase, a key regulatory enzyme of glycolysis in animal tissues. This study was…”
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The two forms of bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase result from alternative splicing by RIDER, M. H, VANDAMME, J, LEBEAU, E, VERTOMMEN, D, VIDAL, H, ROUSSEAU, G. G, VANDEKERCKHOVE, J, HUE, L

“…Purified bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) showed two bands with subunit M(r) of 58,000 and 54,000 when…”
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