Search Results - "RIDA, Padmashree C. G"

Heading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migration by Ogden, Angela, Rida, Padmashree C. G., Aneja, Ritu

“…The complicity of centrosomes in carcinogenesis is unmistakable. Mounting evidence clearly implicates a robust correlation between centrosome amplification…”
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Benefits of whole ginger extract in prostate cancer by Karna, Prasanthi, Chagani, Sharmeen, Gundala, Sushma R., Rida, Padmashree C. G., Asif, Ghazia, Sharma, Vibhuti, Gupta, Meenakshi V., Aneja, Ritu

“…It is appreciated far and wide that increased and regular consumption of fruits and vegetables is linked with noteworthy anticancer benefits. Extensively…”
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How to be good at being bad: centrosome amplification and mitotic propensity drive intratumoral heterogeneity by Rida, Padmashree C. G., Cantuaria, Guilherme, Reid, Michelle D., Kucuk, Omer, Aneja, Ritu

“…Cancer is truly an iconic disease—a tour de force whose multiple formidable strengths can be attributed to the bewildering heterogeneity that a tumor can…”
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A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas by Mittal, Karuna, Choi, Da Hoon, Klimov, Sergey, Pawar, Shrikant, Kaur, Ramneet, Mitra, Anirban K, Gupta, Meenakshi V, Sams, Ralph, Cantuaria, Guilherme, Rida, Padmashree C G, Aneja, Ritu

“…Amplified centrosomes are widely recognized as a hallmark of cancer. Although supernumerary centrosomes would be expected to compromise cell viability by…”
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Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations by Wright, Nikita, Xia, Jun, Cantuaria, Guilherme, Klimov, Sergey, Jones, Mildred, Neema, Pranay, Il'yasova, Dora, Krishnamurti, Uma, Li, Xiaoxian, Reid, Michelle D, Gupta, Meenakshi, Rida, Padmashree C G, Osan, Remus, Aneja, Ritu

“…Clinical studies have revealed a higher risk of breast tumor recurrence in African-American (AA) patients compared to European-American (EA) patients,…”
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Prognostic value of CA20, a score based on centrosome amplification-associated genes, in breast tumors by Ogden, Angela, Rida, Padmashree C. G., Aneja, Ritu

“…Centrosome amplification (CA) is a hallmark of cancer, observable in ≥75% of breast tumors. CA drives aggressive cellular phenotypes such as chromosomal…”
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Centrosome amplification: a suspect in breast cancer and racial disparities by Ogden, Angela, Rida, Padmashree C G, Aneja, Ritu

“…The multifaceted involvement of centrosome amplification (CA) in tumorigenesis is coming into focus following years of meticulous experimentation, which have…”
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Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse by Ogden, Angela, Rida, Padmashree C.G, Knudsen, Beatrice S, Kucuk, Omer, Aneja, Ritu

“…Highlights • Docetaxel promotes the formation of giant, multinucleated cells. • Polyploid cells often exhibit centrosome amplification and aggressive behavior…”
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Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment by Saxena, Roopali, Yang, Chunhua, Rao, Mukkavilli, Turaga, Ravi Chakra, Garlapati, Chakravarthy, Gundala, Sushma Reddy, Myers, Kimberly, Ghareeb, Ahmed, Bhattarai, Shristi, Kamalinia, Golnaz, Bristi, Sangina, Su, Dan, Gadda, Giovanni, Rida, Padmashree C G, Cantuaria, Guilherme H, Aneja, Ritu

“…Most currently available chemotherapeutic agents target rampant cell division in cancer cells, thereby affecting rapidly dividing normal cells resulting in…”
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Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma by Mittal, Karuna, Ogden, Angela, Reid, Michelle D, Rida, Padmashree C G, Varambally, Sooryanarayana, Aneja, Ritu

“…Centrosome amplification (CA), the presence of centrosomes that are abnormally numerous or enlarged, is a well-established driver of tumor initiation and…”
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A novel microtubule-modulating agent EM011 inhibits angiogenesis by repressing the HIF-1α axis and disrupting cell polarity and migration by KARNA, Prasanthi, RIDA, Padmashree C. G, CHAKRA TURAGA, Ravi, JINMIN GAO, GUPTA, Meenakshi, FRITZ, Andreas, WERNER, Erica, YATES, Clayton, JUN ZHOU, ANEJA, Ritu

“…Endothelial tubular morphogenesis relies on an exquisite interplay of microtubule dynamics and actin remodeling to propel directed cell migration. Recently,…”
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Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis by Donthamsetty, Shashikiran, Brahmbhatt, Meera, Pannu, Vaishali, Rida, Padmashree, Ramarathinam, Sujatha, Ogden, Angela, Cheng, Alice, Singh, Keshav K., Aneja, Ritu

“…Centrosomes direct spindle morphogenesis to assemble a bipolar mitotic apparatus to enable error-free chromosome segregation and preclude chromosomal…”
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The Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical Applications by Rida, Padmashree C. G., LiVecche, Dillon, Ogden, Angela, Zhou, Jun, Aneja, Ritu

“…Given its manifold potential therapeutic applications and amenability to modification, noscapine is a veritable “Renaissance drug” worthy of commemoration…”
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Non‐toxic melanoma therapy by a novel tubulin‐binding agent by Aneja, Ritu, Asress, Seneshaw, Dhiman, Neerupma, Awasthi, Anshumali, Rida, Padmashree C.G., Arora, Sudarshan K., Zhou, Jun, Glass, Jonathan D., Joshi, Harish C.

“…(S)‐3‐((R)‐9‐bromo‐4‐methoxy‐6‐methyl‐5,6,7,8‐tetrahydro‐[1,3]dioxolo[4,5‐g]isoquino‐lin‐5‐yl)‐6,7‐dimethoxyisobenzofuran‐1(3H)‐one (EM011) is a…”
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Die-hard survivors: heterogeneity in apoptotic thresholds may underlie chemoresistance by Ogden, Angela, Rida, Padmashree CG, Reid, Michelle D, Kucuk, Omer, Aneja, Ritu

“…The unmatched efficacy of microtubule-targeting agents (MTAs) as chemotherapeutics was once assumed to originate from their impact on mitotic processes;…”
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Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer by Mittal, Karuna, Donthamsetty, Shashi, Kaur, Ramneet, Yang, Chunhua, Gupta, Meenakshi V, Reid, Michelle D, Choi, Da Hoon, Rida, Padmashree C G, Aneja, Ritu

“…Background: Docetaxel is the only FDA-approved first-line treatment for castration-resistant prostate cancer (CRPC) patients. Docetaxel treatment inevitably…”
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Application of Combination High‐Throughput Phenotypic Screening and Target Identification Methods for the Discovery of Natural Product‐Based Combination Drugs by Isgut, Monica, Rao, Mukkavilli, Yang, Chunhua, Subrahmanyam, Vangala, Rida, Padmashree C. G., Aneja, Ritu

“…Modern drug discovery efforts have had mediocre success rates with increasing developmental costs, and this has encouraged pharmaceutical scientists to seek…”
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Yeast-to-hyphal transition triggers formin-dependent Golgi localization to the growing tip in Candida albicans by Rida, Padmashree C G, Nishikawa, Akiko, Won, Gena Y, Dean, Neta

“…Rapid and long-distance secretion of membrane components is critical for hyphal formation in filamentous fungi, but the mechanisms responsible for polarized…”
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Tackling intra- and inter-tumor heterogeneity to combat triple negative breast cancer by Wright, Nikita, Rida, Padmashree C G, Aneja, Ritu

“…Rampant inter-patient and intra-tumor heterogeneity present formidable challenges in the clinical management of triple-negative breast cancer (TNBC) and…”
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A novel prognostic two-gene signature for triple negative breast cancer by Alsaleem, Mansour A., Ball, Graham, Toss, Michael S., Raafat, Sara, Aleskandarany, Mohammed, Joseph, Chitra, Ogden, Angela, Bhattarai, Shristi, Rida, Padmashree C.G., Khani, Francesca, Davis, Melissa, Elemento, Olivier, Aneja, Ritu, Ellis, Ian O., Green, Andrew, Mongan, Nigel P., Rakha, Emad

“…The absence of a robust risk stratification tool for triple negative breast cancer (TNBC) underlies imprecise and nonselective treatment of these patients with…”
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