Search Results - "RICOTTI, Emanuela"
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cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression
Published in Haematologica (Roma) (01-10-2007)“…* From the Department of Pediatrics, Laboratory of Pediatric Onco-Hematology, University of Padova, Padova, Italy ° Department of Pediatrics, University of…”
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Long-term modifications of the peripheral immune repertoire after switching from sequestering disease-modifying treatments in multiple sclerosis
Published in Multiple sclerosis (07-10-2024)“…Scarce data are available on the long-term immunological effects of multiple sclerosis (MS) disease-modifying treatments (DMTs). This study aimed to…”
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Peculiar immunophenotypic signature in MIS‐C‐affected children
Published in Pediatric allergy and immunology (01-05-2021)Get full text
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Immunophenotype Anomalies Predict the Development of Autoimmune Cytopenia in 22q11.2 Deletion Syndrome
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-09-2019)“…Patients with 22q11.2 deletion syndrome (22q11.2DS) may develop severe thrombocytopenic purpura and hemolytic anemia. There are no reliable predictors for the…”
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Aberrantly glycosylated IgA1 induces mesangial cells to produce platelet-activating factor that mediates nephrin loss in cultured podocytes
Published in Kidney international (01-03-2010)“…The reaction of mesangial cells with aberrantly glycosylated IgA1 has been implicated in the etiology of IgA nephropathy (IgAN). Tumor necrosis factor, which…”
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Low synovial double negative T and γδ T cells predict longer free‐disease survival in oligoarticular JIA
Published in Cytometry. Part B, Clinical cytometry (01-05-2018)“…Background Oligoarticular juvenile idiopathic arthritis (oJIA) is the most frequent form of chronic arthritis in children; the clinical course is extremely…”
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In vitro anti-neuroblastoma activity of saquinavir and its association with imatinib
Published in Oncology reports (01-03-2012)“…Neuroblastoma (NB) has a poor prognosis when in advanced stages, highlighting the need for new therapeutic options. The human immunodeficiency virus (HIV)…”
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In CD28-costimulated human naïve CD4⁺ T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms
Published in Immunology (01-10-2010)“…Stimulation of naïve CD4⁺ T cells through engagement of the T-cell receptor (TCR) and the CD28 co-receptor initiates cell proliferation which critically…”
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The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function
Published in Antiviral therapy (01-01-2005)“…In HIV-infected patients some clinical and immunological benefits of antiretroviral therapy, which frequently include a combination of HIV protease inhibitors…”
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CAMP response element binding protein (CREB) overexpression has been described as critical for leukemia progression
Published in Haematologica (Roma) (01-10-2007)Get full text
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In CD28-costimulated human naïve CD4+ T cells, I-[kappa]B kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms
Published in Immunology (01-10-2010)“…Summary Stimulation of naïve CD4+ T cells through engagement of the T-cell receptor (TCR) and the CD28 co-receptor initiates cell proliferation which…”
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In CD28-costimulated human naieve CD4+ T cells, I-B kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms
Published in Immunology (01-10-2010)“…SummaryStimulation of naieve CD4+ T cells through engagement of the T-cell receptor (TCR) and the CD28 co-receptor initiates cell proliferation which…”
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The human 26S proteasome is a target of antiretroviral agents
Published in AIDS (London) (29-03-2002)“…Proteasomes constitute the degradative machinery of the ubiquitin/adenosine triphosphate-dependent proteolytic pathway, which is involved in many cell…”
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Analyses of the Inducible Cyclic Adenosine 3′,5′-Monophosphate Early Repressor (ICER) and cAMP Response Element Binding Protein (CREB) in HL60 Cells: New Insight Leukemogenesis?
Published in Blood (16-11-2006)“…The cyclic AMP response-element binding protein (CREB) is a transcription factor that controls genes that regulate cell differentiation, proliferation and…”
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The effects of saquinavir on imatinib-resistant chronic myelogenous leukemia cell lines
Published in Haematologica (Roma) (01-05-2006)“…We evaluated the effect of the human immunodeficiency virus (HIV) protease inhibitor saquinavir on the imatinib-sensitive and imatinib-resistant chronic…”
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Immunomodulatory effects of two HIV protease inhibitors, Saquinavir and Ritonavir, on lymphocytes from healthy seronegative individuals
Published in Immunology Letters (15-08-2007)“…Abstract Immunological and clinical benefits of highly active antiretroviral therapy (HAART) do not always correlate with its efficacy in controlling HIV…”
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Nitric oxide mediates cyclosporine-induced apoptosis in cultured renal cells
Published in Kidney international (01-04-2000)“…Nitric oxide mediates cyclosporine-induced apoptosis in cultured renal cells. The clinical use of cyclosporine (CsA) is limited by its nephrotoxicity…”
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c-kit Is Expressed in Soft Tissue Sarcoma of Neuroectodermic Origin and Its Ligand Prevents Apoptosis of Neoplastic Cells
Published in Blood (01-04-1998)“…During development, mice with mutations of stem cell factor (SCF) or its receptor c-kit exhibit defects in melanogenesis, as well as hematopoiesis and…”
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Imatinib mesylate (STI571) interference with growth of neuroectodermal tumour cell lines does not critically involve c-Kit inhibition
Published in International journal of molecular medicine (01-09-2004)“…A therapeutic role of STI571 (imatinib mesylate) has been anticipated in patients with c-Kit positive neuroectodermal tumors. We examined the efficacy of…”
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Human immunodeficiency virus infection as risk factor for mother-to-child hepatitis C virus transmission; persistence of anti-hepatitis C virus in children is associated with the mother's anti-hepatitis C virus immunoblotting pattern
Published in Hepatology (Baltimore, Md.) (01-02-1995)“…To determine the rate of vertical transmission of hepatitis C virus (HCV), we prospectively studied 45 babies born to anti-HCV-positive women with or without…”
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