Search Results - "RICHARDSON, S. J"

prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes by Richardson, S. J, Willcox, A, Bone, A. J, Foulis, A. K, Morgan, N. G

“…Aims/hypothesis Evidence that the beta cells of human patients with type 1 diabetes can be infected with enterovirus is accumulating, but it remains unclear…”
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Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes by Marhfour, I., Lopez, X. M., Lefkaditis, D., Salmon, I., Allagnat, F., Richardson, S. J., Morgan, N. G., Eizirik, D. L.

“…Aims/hypothesis Endoplasmic reticulum (ER) stress may play a role in cytokine-mediated beta cell death in type 1 diabetes, but it remains controversial whether…”
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Islet-associated macrophages in type 2 diabetes by Richardson, S. J, Willcox, A, Bone, A. J, Foulis, A. K, Morgan, N. G

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The diagnosis of insulitis in human type 1 diabetes by Campbell-Thompson, M. L., Atkinson, M. A., Butler, A. E., Chapman, N. M., Frisk, G., Gianani, R., Giepmans, B. N., von Herrath, M. G., Hyöty, H., Kay, T. W., Korsgren, O., Morgan, N. G., Powers, A. C., Pugliese, A., Richardson, S. J., Rowe, P. A., Tracy, S., In’t Veld, P. A.

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Analysis of islet inflammation in human type 1 diabetes by Willcox, A, Richardson, S.J, Bone, A.J, Foulis, A.K, Morgan, N.G

“…The immunopathology of type 1 diabetes (T1D) has proved difficult to study in man because of the limited availability of appropriate samples, but we now report…”
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Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients by Caton, P. W., Richardson, S. J., Kieswich, J., Bugliani, M., Holland, M. L., Marchetti, P., Morgan, N. G., Yaqoob, M. M., Holness, M. J., Sugden, M. C.

“…Aims/hypothesis Sirtuin (SIRT)3 is a mitochondrial protein deacetylase that regulates reactive oxygen species (ROS) production and exerts anti-inflammatory…”
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The Diversity of Mechanisms Influenced by Transthyretin in Neurobiology: Development, Disease and Endocrine Disruption by Alshehri, B., D'Souza, D. G., Lee, J. Y., Petratos, S., Richardson, S. J.

“…Transthyretin (TTR) is a protein that binds and distributes thyroid hormones (THs). TTR synthesised in the liver is secreted into the bloodstream and…”
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Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1 by Richardson, S. J., Leete, P., Bone, A. J., Foulis, A. K., Morgan, N. G.

“…Aims/hypothesis Immunohistochemical staining reveals that the enteroviral capsid protein VP1 is present at higher frequency in the insulin-containing islets of…”
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Assessment of uncertainties of an aircraft-based mass balance approach for quantifying urban greenhouse gas emissions by Cambaliza, M. O. L, Shepson, P. B, Caulton, D. R, Stirm, B, Samarov, D, Gurney, K. R, Turnbull, J, Davis, K. J, Possolo, A, Karion, A, Sweeney, C, Moser, B, Hendricks, A, Lauvaux, T, Mays, K, Whetstone, J, Huang, J, Razlivanov, I, Miles, N. L, Richardson, S. J

“…Urban environments are the primary contributors to global anthropogenic carbon emissions. Because much of the growth in CO2 emissions will originate from…”
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High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air by Rella, C. W, Chen, H, Andrews, A. E, Filges, A, Gerbig, C, Hatakka, J, Karion, A, Miles, N. L, Richardson, S. J, Steinbacher, M, Sweeney, C, Wastine, B, Zellweger, C

“…Traditional techniques for measuring the mole fractions of greenhouse gases in the well-mixed atmosphere have required dry sample gas streams (dew point < −25…”
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An indigenous community-based monitoring system for assessing forest health in New Zealand by Lyver, P. O’. B., Timoti, P., Jones, C. J., Richardson, S. J., Tahi, B. L., Greenhalgh, S.

“…The underlying ethos of ‘nature’s benefits’ contributing to human wellbeing provides a common platform for understanding the function and value of biodiversity…”
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Thyroid Hormone Signaling in the Xenopus laevis Embryo Is Functional and Susceptible to Endocrine Disruption by Fini, J. B, Mével, S. Le, Palmier, K, Darras, V. M, Punzon, I, Richardson, S. J, Clerget-Froidevaux, M. S, Demeneix, B. A

“…Thyroid hormone (TH) is essential for vertebrate brain development. Most research on TH and neuronal development focuses on late development, mainly the…”
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Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children by Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, L. G., Morgan, N. G., Mandrup-Poulsen, T.

“…Aims/hypothesis Histone deacetylases (HDACs) are promising pharmacological targets in cancer and autoimmune diseases. All 11 classical HDACs (HDAC1–11) are…”
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Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes by Willcox, A, Richardson, S. J, Bone, A. J, Foulis, A. K, Morgan, N. G

“…Aims/hypothesis In adults, the rate of beta cell replication is normally very low, but recent evidence suggests that it may increase during insulitis. We…”
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MolProbity: structure validation and all-atom contact analysis for nucleic acids and their complexes by Davis, Ian W., Murray, Laura Weston, Richardson, Jane S., Richardson, David C.

“…MolProbity is a general-purpose web service offering quality validation for three-dimensional (3D) structures of proteins, nucleic acids and complexes. It…”
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Immunohistochemical analysis of the relationship between islet cell proliferation and the production of the enteroviral capsid protein, VP1, in the islets of patients with recent-onset type 1 diabetes by Willcox, A., Richardson, S. J., Bone, A. J., Foulis, A. K., Morgan, N. G.

“…Aims/hypothesis The enteroviral capsid protein, VP1, was recently shown to be present in some beta cells in more than 60% of patients with recent-onset type 1…”
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The formation of the oceanic temperate forests of New Zealand by McGlone, MS, Buitenwerf, R, Richardson, SJ

“…The pre-clearance New Zealand lowlands were largely in complex, liana-rich, multi-layered conifer-angiosperm forest. Here it is designated oceanic temperate…”
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Long-term ecosystem level experiments at Toolik Lake, Alaska, and at Abisko, Northern Sweden: generalizations and differences in ecosystem and plant type responses to global change by Van Wijk, M.T, Clemmensen, K.E, Shaver, G.R, Williams, M, Callaghan, T.V, Chapin, F.S. III, Cornelissen, J.H.C, Gough, L, Hobbie, S.E, Jonasson, S

“…Long‐term ecosystem‐level experiments, in which the environment is manipulated in a controlled manner, are important tools to predict the responses of…”
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Source Sector Attribution of CO2 Emissions Using an Urban CO/CO2 Bayesian Inversion System by Nathan, B. J., Lauvaux, T., Turnbull, J. C., Richardson, S. J., Miles, N. L., Gurney, K. R.

“…We assimilate multiple trace gas species within a single high‐resolution Bayesian inversion system to optimize CO2ff emissions for individual source sectors…”
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N and P in New Zealand Soil Chronosequences and Relationships with Foliar N and P by Parfitt, R. L., Ross, D. J., Coomes, D. A., Richardson, S. J., Smale, M. C., Dahlgren, R. A.

“…The growth of forest species in soil development chronosequences becomes increasingly phosphorus (P)-limited with time, as P is weathered, eroded and leached…”
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