Search Results - "RICCIARDI, Simona"
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1
Correlation of CDA, ERCC1, and XPD Polymorphisms with Response and Survival in Gemcitabine/Cisplatin–Treated Advanced Non–Small Cell Lung Cancer Patients
Published in Clinical cancer research (15-03-2008)“…Purpose: Selecting patients according to key genetic characteristics may help to tailor chemotherapy and optimize the treatment in non–small cell lung cancer…”
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2
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells
Published in Molecular pharmacology (01-04-2008)“…Because the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib and the multitargeted antifolate pemetrexed are registered in the…”
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3
Arc 3' UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling
Published in Frontiers in molecular neuroscience (27-04-2018)“…Activity-regulated cytoskeletal associated protein (Arc) is an immediate-early gene critically involved in synaptic plasticity and memory consolidation. Arc…”
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4
Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines
Published in Molecular cancer therapeutics (01-07-2009)“…Irinotecan is a topoisomerase-I (Top-I) inhibitor used for the treatment of colorectal cancer. DNA demethylating agents, including 5-azacytidine (5-aza),…”
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Synergistic Antitumor Activity of ZD6474, An Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor Signaling, with Gemcitabine and Ionizing Radiation against Pancreatic Cancer
Published in Clinical cancer research (01-12-2006)“…Purpose: Standard treatments have modest effect against pancreatic cancer, and current research focuses on agents targeting molecular pathways involved in…”
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6
A case of drug resistant clear cell ovarian cancer showing responsiveness to gemcitabine at first administration and at re-challenge
Published in Cancer chemotherapy and pharmacology (01-08-2007)“…Gemcitabine (2',2'-difluorodeoxycytidine) (GEM) has been demonstrated to be active in the salvage setting of ovarian cancer (OC) patients. A 57-year-old woman,…”
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7
Membrane remodeling and trafficking piloted by SARS-CoV-2
Published in Trends in cell biology (01-09-2024)“…High-throughput clustered regularly interspaced short palindromic repeats (CRISPR) screens identified pro- and antiviral host factors.SARS-CoV-2 subverts the…”
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The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle
Published in Nature (London) (23-06-2022)“…SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication organelle to enable RNA replication 1 . The SARS-CoV-2 replication organelle is…”
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Synergistic cytotoxicity, inhibition of signal transduction pathways and pharmacogenetics of sorafenib and gemcitabine in human NSCLC cell lines
Published in Lung cancer (Amsterdam, Netherlands) (01-11-2011)“…Abstract Introduction Lung cancer is one of the most lethal tumors and, although standard chemotherapy produces clinical response, there has been little…”
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Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer
Published in Cancer chemotherapy and pharmacology (01-03-2010)“…Purpose Gemcitabine (2′,2′-difluorodeoxycytidine) (GEM) is one of the most actively investigated drugs in ovarian cancer. Many molecular mechanisms have been…”
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11
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer
Published in ACS medicinal chemistry letters (12-12-2013)“…This study was aimed at investigating the antitumor activity of novel 2-oxindole derivatives against a well-characterized human nonsmall cell lung cancer…”
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12
Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma
Published in Laboratory investigation (01-07-2008)“…A key focus of research on pancreatic ductal adenocarcinoma (PDAC) is identifying new techniques to tailor gemcitabine and 5-fluorouracil treatments…”
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13
Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells
Published in Pharmacological research (01-04-2007)“…Gemcitabine is an inhibitor of ribonucleotide reductase (RR) and DNA polymerization with promising activity in hematologic malignancies. Gemcitabine enters the…”
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Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines
Published in Cancer chemotherapy and pharmacology (01-08-2010)“…Purpose Oxaliplatin effect in the treatment of colorectal cancer is improved upon combination with thymidylate synthase (TS) inhibitors. Pemetrexed is…”
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15
Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells
Published in Chemotherapy (Basel) (01-01-2010)“…Current treatments have a modest impact on survival of pancreatic cancer patients and this study investigates the interaction between sorafenib and gemcitabine…”
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Direzionalità e Condensazione del movimento corporeo attraverso uno strumento di auto-valutazione
Published in Phenomena journal (01-05-2020)“…Movement can provide information about the way people express themselves and interacting with others. Scientific studies support the importance of non- verbal…”
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L’utilità dello Zulliger Test nella valutazione del funzionamento psichico
Published in Phenomena journal (01-06-2019)“…The Zulliger Test (or Z-Test) is a projective technique elaborated by Hans Zulliger (1893-1965), both in the individual form and in the collective form. It is…”
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