Search Results - "RICART, Wifredo"
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Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
Published in Nature Medicine (01-07-2018)“…Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is a prelude to non-alcoholic fatty liver disease. Here, we…”
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Targeting the circulating microRNA signature of obesity
Published in Clinical chemistry (Baltimore, Md.) (01-05-2013)“…Genomic studies have yielded important insights into the pathogenesis of obesity. Circulating microRNAs (miRNAs) are valuable biomarkers of systemic diseases…”
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Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance
Published in PloS one (18-05-2012)“…Zonulin is the only physiological mediator known to regulate intestinal permeability reversibly by modulating intercellular tight junctions. To investigate the…”
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Obesity changes the human gut mycobiome
Published in Scientific reports (12-10-2015)“…The human intestine is home to a diverse range of bacterial and fungal species, forming an ecological community that contributes to normal physiology and…”
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Insulin Resistance and Chronic Cardiovascular Inflammatory Syndrome
Published in Endocrine reviews (01-06-2003)“…Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state. Hyperinsulinemia and insulin action were initially proposed as the…”
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Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
Published in Microbiome (30-04-2020)“…The chaperone ClpB, a bacterial protein, is a conformational antigen-mimetic of α-melanocyte-stimulating hormone (α-MSH) implicated in body weight regulation…”
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MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation
Published in PloS one (02-02-2010)“…Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially…”
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Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome
Published in Microbiome (07-05-2021)“…The gut microbiome and iron status are known to play a role in the pathophysiology of non-alcoholic fatty liver disease (NAFLD), although their complex…”
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Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects
Published in Frontiers in physiology (10-07-2019)“…Aging is a physiological process known to produce changes in body composition, affecting the musculature and leading to decreased muscle strength. Muscle in…”
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Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue
Published in Frontiers in physiology (31-01-2019)“…Nrg4 expression has been linked to brown adipose tissue activity and browning of white adipocytes in mice. Here, we aimed to investigate whether these…”
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Circulating omentin concentration increases after weight loss
Published in Nutrition & metabolism (09-04-2010)“…Omentin-1 is a novel adipokine expressed in visceral adipose tissue and negatively associated with insulin resistance and obesity. We aimed to study the…”
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Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects
Published in PloS one (21-04-2015)“…A physically active life-style plays an independent role in the protection against type 2 diabetes and cardiovascular diseases. Irisin, a novel…”
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Circulating Omentin as a Novel Biomarker of Endothelial Dysfunction
Published in Obesity (Silver Spring, Md.) (01-08-2011)“…Omentin is a novel soluble lectin expressed mainly in the stromal‐vascular cells from visceral adipose tissue with vasodilator effect in isolated blood…”
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Morbidly obese subjects show increased serum sulfide in proportion to fat mass
Published in International Journal of Obesity (01-02-2021)“…Background and objectives The importance of hydrogen sulfide is increasingly recognized in the pathophysiology of obesity and type 2 diabetes in animal models…”
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15
Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition
Published in Acta diabetologica (09-05-2019)“…Aims To investigate the interactions among fecal and plasma glutamate levels, insulin resistance cognition and gut microbiota composition in obese and…”
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Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence
Published in Nature communications (22-08-2023)“…Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention…”
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The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity
Published in Biomedicine & pharmacotherapy (01-12-2022)“…To investigate the potential role of EGFR, ErbBs receptors and neuregulins in human adipose tissue physiology in obesity. Gene expression analysis in human…”
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Circulating profiling reveals the effect of a polyunsaturated fatty acid-enriched diet on common microRNAs
Published in The Journal of nutritional biochemistry (01-10-2015)“…Consumption of long-chain polyunsaturated fatty acids (PUFAs), which are abundant in seafood and nuts, ameliorates components of the metabolic syndrome…”
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Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles
Published in International journal of molecular sciences (30-11-2021)“…The adipokine Neuregulin 4 (Nrg4) protects against obesity-induced insulin resistance. Here, we analyze how the downregulation of Nrg4 influences insulin…”
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Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation
Published in Diabetologia (01-10-2015)“…Aims/hypothesis Lipopolysaccharide (LPS) binding protein (LBP) is a novel 65 kDa adipokine, linked to adipose tissue (AT) inflammation, obesity and insulin…”
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