Search Results - "RIA, L."

Evaluation of four KCNMA1 channelopathy variants on BK channel current under CaV1.2 activation by Dinsdale, Ria L, Meredith, Andrea L

“…Variants in KCNMA1, encoding the voltage- and calcium-activated K+ (BK) channel, are associated with human neurological disease. The effects of…”
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Cements and concretes materials characterisation using machine‐learning‐based reconstruction and 3D quantitative mineralogy via X‐ray microscopy by Mitchell, Ria L., Holwell, Andy, Torelli, Giacomo, Provis, John, Selvaranjan, Kajanan, Geddes, Dan, Yorkshire, Antonia, Kearney, Sarah

“…3D imaging via X‐ray microscopy (XRM), a form of tomography, is revolutionising materials characterisation. Nondestructive imaging to classify grains,…”
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Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models by Dinsdale, Ria L, Roache, Cooper E, Meredith, Andrea L

“…KCNMA1 encodes the voltage- and calcium-activated K+ (BK) channel, which regulates suprachiasmatic nucleus (SCN) neuronal firing and circadian behavioral…”
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An outer-pore gate modulates the pharmacology of the TMEM16A channel by Dinsdale, Ria L., Pipatpolkai, Tanadet, Agostinelli, Emilio, Russell, Angela J., Stansfeld, Phillip J., Tammaro, Paolo

“…TMEM16A Ca2+-activated chloride channels are involved in multiple cellular functions and are proposed targets for diseases such as hypertension, stroke, and…”
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Evaluation of four KCNMA1 channelopathy variants on BK channel current under Ca V 1.2 activation by Dinsdale, Ria L, Meredith, Andrea L

“…Variants in , encoding the voltage- and calcium-activated K (BK) channel, are associated with human neurological disease. The effects of gain-of-function (GOF)…”
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Biologically mediated weathering in modern cryptogamic ground covers and the early Paleozoic fossil record by Mitchell, Ria L., Strullu-Derrien, Christine, Kenrick, Paul

“…Specific micro-weathering features and biochemically derived residues formed by living organisms can be used as biomarkers to infer the presence of biological…”
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Correlating Local Volumetric Tissue Strains with Global Lung Mechanics Measurements by Arora, Hari, Mitchell, Ria L, Johnston, Richard, Manolesos, Marinos, Howells, David, Sherwood, Joseph M, Bodey, Andrew J, Wanelik, Kaz

“…The mechanics of breathing is a fascinating and vital process. The lung has complexities and subtle heterogeneities in structure across length scales that…”
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Geometrical control of eddy currents in additively manufactured Fe-Si by Goodall, Alexander D., Yiannakou, Georgios, Chechik, Lova, Mitchell, Ria L., Jewell, Geraint W, Todd, Iain

“…[Display omitted] •Simulations shown to match experimental losses in solid cross-section of Fe-6.5 wt%Si.•Air gaps in the cross section are used to improve…”
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In situ TiC reinforced Ti6Al4V matrix composites manufactured via selective laser melting by Gülenç, İdris Tuğrul, Bai, Mingwen, Mitchell, Ria L., Todd, Iain, Inkson, Beverley J.

“…Purpose Current methods for the preparation of composite powder feedstock for selective laser melting (SLM) rely on costly nanoparticles or yield inconsistent…”
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Sedimentary provenance and weathering processes in the 1.1 Ga Midcontinental Rift of the Keweenaw Peninsula, Michigan, USA by Mitchell, Ria L., Sheldon, Nathan D.

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Synthesis and Characterization of High-Performance Renewable Diesel Fuel from Bioderived 1‑Octen-3-ol by Siirila, Michael J, Zeng, Manhao, Woodroffe, Josanne-Dee, Askew, Ria L, Harvey, Benjamin G

“…1-Octen-3-ol, a renewable alcohol that can be readily derived from linoleic acid, was dehydrated to a mixture of conjugated octadienes. Diels–Alder…”
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Biologically-mediated weathering in modern cryptogamic ground covers and the lower Palaeozoic fossil record by Mitchell, Ria L, Strullu-Derrien, Christine, Kenrick, Paul

“…Specific micro-weathering features and biochemically-derived residues formed by living organisms can be used as biomarkers to infer the presence of biological…”
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Terrestrial surface stabilisation by modern analogues of the earliest land plants: A multi‐dimensional imaging study by Mitchell, Ria L., Kenrick, Paul, Pressel, Silvia, Duckett, Jeff, Strullu‐Derrien, Christine, Davies, Neil, McMahon, William J., Summerfield, Rebecca

“…The evolution of the first plant‐based terrestrial ecosystems in the early Palaeozoic had a profound effect on the development of soils, the architecture of…”
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Cryptogamic ground covers as analogues for early terrestrial biospheres: Initiation and evolution of biologically mediated proto‐soils by Mitchell, Ria L., Strullu‐Derrien, Christine, Sykes, Dan, Pressel, Silvia, Duckett, Jeffrey G., Kenrick, Paul

“…Modern cryptogamic ground covers (CGCs), comprising assemblages of bryophytes (hornworts, liverworts, mosses), fungi, bacteria, lichens and algae, are thought…”
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Effect of antimony additions on the microstructure and performance of Zn–Mg–Al alloy coatings by Britton, Daniel A., Penney, David, Malla, Amar D., Mehraban, Shahin, Sullivan, James, Goldsworthy, Mathew, McGettrick, James, Johnston, Richard, Mitchell, Ria L., Challinor, Clive

“…Microscopy, electrochemical techniques and mechanical testing are used to investigate the effect of varying antimony additions (0.45–1.8 wt%) on the…”
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Mice Deficient for Soluble Adenylyl Cyclase Are Infertile because of a Severe Sperm-Motility Defect by Esposito, Gloria, Jaiswal, Byjay S., Xie, Fang, Magda A. M. Krajnc-Franken, Tamara J. A. A. Robben, Strik, Ankie M., Kuil, Cor, Ria L. A. Philipsen, van Duin, Marcel, Conti, Marco, Gossen, Jan A., Beavo, Joseph A.

“…To acquire the ability to fertilize, spermatozoa undergo complex, but at present poorly understood, activation processes. The intracellular rise of cAMP…”
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The ∼1100Ma Sturgeon Falls paleosol revisited: Implications for Mesoproterozoic weathering environments and atmospheric CO2 levels by Mitchell, Ria L., Sheldon, Nathan D.

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Effect of an autism-associated KCNMB2 variant, G124R, on BK channel properties by Moldenhauer, Hans J., Dinsdale, Ria L., Alvarez, Sara, Fernández-Jaén, Alberto, Meredith, Andrea L.

“…BK K + channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and…”
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Nationwide Study on the Course of Influenza A (H1N1) Infections in Hospitalized Children in the Netherlands During the Pandemic 2009–2010 by Ahout, Inge M L, Philipsen, Ria L A, Las, Mariëtte, Baysan, Meryem, Brus, Frank, Rahamat-Langendoen, Jeanette C, Roeleveld, Nel, Fraaij, Pieter L, Osterhaus, Albert D. M E, Ferwerda, Gerben, de Groot, Ronald

“…BACKGROUND:The influenza H1N1 pandemic of 2009–2010, provided a unique opportunity to assess the course of disease, as well as the analysis of risk factors for…”
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Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni by Partridge, Frederick A, Bataille, Carole J.R, Forman, Ruth, Marriott, Amy E, Forde-Thomas, Josephine, Häberli, Cécile, Dinsdale, Ria L, O’Sullivan, James D.B, Willis, Nicky J, Wynne, Graham M, Whiteland, Helen, Archer, John, Steven, Andrew, Keiser, Jennifer, Turner, Joseph D, Hoffmann, Karl F, Taylor, Mark J, Else, Kathryn J, Russell, Angela J, Sattelle, David B

“…Nine hundred million people are infected with the soil-transmitted helminths Ascaris lumbricoides (roundworm), hookworm, and Trichuris trichiura (whipworm)…”
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