Search Results - "REYNOLDS, James D"

P7C3-A20 treatment one year after TBI in mice repairs the blood–brain barrier, arrests chronic neurodegeneration, and restores cognition by Vázquez-Rosa, Edwin, Shin, Min-Kyoo, Dhar, Matasha, Chaubey, Kalyani, Cintrón-Pérez, Coral J., Tang, Xinmiao, Liao, Xudong, Miller, Emiko, Koh, Yeojung, Barker, Sarah, Franke, Kathryn, Crosby, Danyel R., Schroeder, Rachel, Emery, Josie, Yin, Terry C., Fujioka, Hisashi, Reynolds, James D., Harper, Matthew M., Jain, Mukesh K., Pieper, Andrew A.

“…Chronic neurodegeneration in survivors of traumatic brain injury (TBI) is a major cause of morbidity, with no effective therapies to mitigate this progressive…”
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Hemoglobin βCys93 is essential for cardiovascular function and integrated response to hypoxia by Zhang, Rongli, Hess, Douglas T., Qian, Zhaoxia, Hausladen, Alfred, Fonseca, Fabio, Chaube, Ruchi, Reynolds, James D., Stamler, Jonathan S.

“…Oxygen delivery by Hb is essential for vertebrate life. Three amino acids in Hb are strictly conserved in all mammals and birds, but only two of those, a His…”
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S-nitrosohemoglobin deficiency: A mechanism for loss of physiological activity in banked blood by Reynolds, James D, Ahearn, Gregory S, Angelo, Michael, Zhang, Jian, Cobb, Fred, Stamler, Jonathan S

“…RBCs distribute oxygen to tissues, but, paradoxically, blood transfusion does not always improve oxygen delivery and is associated with ischemic events. We…”
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Expert Diagnosis of Plus Disease in Retinopathy of Prematurity From Computer-Based Image Analysis by Campbell, J Peter, Ataer-Cansizoglu, Esra, Bolon-Canedo, Veronica, Bozkurt, Alican, Erdogmus, Deniz, Kalpathy-Cramer, Jayashree, Patel, Samir N, Reynolds, James D, Horowitz, Jason, Hutcheson, Kelly, Shapiro, Michael, Repka, Michael X, Ferrone, Phillip, Drenser, Kimberly, Martinez-Castellanos, Maria Ana, Ostmo, Susan, Jonas, Karyn, Chan, R V Paul, Chiang, Michael F

“…Published definitions of plus disease in retinopathy of prematurity (ROP) reference arterial tortuosity and venous dilation within the posterior pole based on…”
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Describing Retinopathy of Prematurity: Current Limitations and New Challenges by Fielder, Alistair R., Wallace, David K., Stahl, Andreas, Reynolds, James D., Chiang, Michael F., Quinn, Graham E.

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S-Nitrosylated hemoglobin predicts organ yield in neurologically-deceased human donors by Nazemian, Ryan, Matta, Maroun, Aldamouk, Amer, Zhu, Lin, Awad, Mohamed, Pophal, Megan, Palmer, Nicole R., Armes, Tonya, Hausladen, Alfred, Stamler, Jonathan S., Reynolds, James D.

“…Current human donor care protocols following death by neurologic criteria (DNC) can stabilize macro-hemodynamic parameters but have minimal ability to preserve…”
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Single‐Contact, Four‐Terminal Microelectromechanical Relay for Efficient Digital Logic by Reynolds, James D., Rana, Sunil, Worsey, Elliott, Tang, Qi, Kulsreshath, Mukesh K., Chong, Harold M. H., Pamunuwa, Dinesh

“…Nano and microelectromechanical relays can be used in lieu of transistors to build digital integrated circuits that can operate with zero leakage current at…”
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S-nitrosylation therapy to improve oxygen delivery of banked blood by Reynolds, James D., Bennett, Kyla M., Cina, Anthony J., Diesen, Diana L., Henderson, Matthew B., Matto, Faisal, Plante, Andrew, Williamson, Rachel A., Zandinejad, Keivan, Demchenko, Ivan T., Hess, Douglas T., Piantadosi, Claude A., Stamler, Jonathan S.

“…From the perspectives of disease transmission and sterility maintenance, the world’s blood supplies are generally safe. However, in multiple clinical settings,…”
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Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial by Stahl, Andreas, Lepore, Domenico, Fielder, Alistair, Fleck, Brian, Reynolds, James D, Chiang, Michael F, Li, Jun, Liew, Melissa, Maier, Rainer, Zhu, Qi, Marlow, Neil

“…Despite increasing worldwide use of anti-vascular endothelial growth factor agents for treatment of retinopathy of prematurity (ROP), there are few data on…”
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Airway Thiol-NO Adducts as Determinants of Exhaled NO by Pophal, Megan, Grimmett, Zachary W, Chu, Clara, Margevicius, Seunghee, Raffay, Thomas, Ross, Kristie, Jafri, Anjum, Giddings, Olivia, Stamler, Jonathan S, Gaston, Benjamin, Reynolds, James D

“…Thiol-NO adducts such as -nitrosoglutathione (GSNO) are endogenous bronchodilators in human airways. Decreased airway -nitrosothiol concentrations are…”
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Role of Nitric Oxide Carried by Hemoglobin in Cardiovascular Physiology: Developments on a Three-Gas Respiratory Cycle by Premont, Richard T., Reynolds, James D., Zhang, Rongli, Stamler, Jonathan S.

“…A continuous supply of oxygen is essential for the survival of multicellular organisms. The understanding of how this supply is regulated in the…”
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International Classification of Retinopathy of Prematurity, Third Edition by Chiang, Michael F., Quinn, Graham E., Fielder, Alistair R., Ostmo, Susan R., Paul Chan, R.V., Berrocal, Audina, Binenbaum, Gil, Blair, Michael, Peter Campbell, J., Capone, Antonio, Chen, Yi, Dai, Shuan, Ells, Anna, Fleck, Brian W., Good, William V., Hartnett, M. Elizabeth, Holmstrom, Gerd, Kusaka, Shunji, Kychenthal, Andrés, Lepore, Domenico, Lorenz, Birgit, Martinez-Castellanos, Maria Ana, Özdek, Şengül, Ademola-Popoola, Dupe, Reynolds, James D., Shah, Parag K., Shapiro, Michael, Stahl, Andreas, Toth, Cynthia, Vinekar, Anand, Visser, Linda, Wallace, David K., Wu, Wei-Chi, Zhao, Peiquan, Zin, Andrea

“…The International Classification of Retinopathy of Prematurity is a consensus statement that creates a standard nomenclature for classification of retinopathy…”
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Can Nitric Oxide–Based Therapy Prevent Bronchopulmonary Dysplasia? by Raffay, Thomas M., MD, Martin, Richard J., MD, Reynolds, James D., PhD

“…A growing understanding of endogenous nitric oxide (NO) biology is helping to explain how and when exogenous NO may confer benefit or harm; this knowledge is…”
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Hemoglobin S-nitrosylation plays an essential role in cardioprotection by Zhang, Rongli, Hess, Douglas T, Reynolds, James D, Stamler, Jonathan S

“…Homeostatic control of tissue oxygenation is achieved largely through changes in blood flow that are regulated by the classic physiological response of hypoxic…”
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Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse by Premont, Richard T, Reynolds, James D, Zhang, Rongli, Stamler, Jonathan S

“…Red blood cell (RBC)-mediated vasodilation plays an important role in oxygen delivery. This occurs through hemoglobin actions, at least in significant part, to…”
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Bevacizumab for Retinopathy of Prematurity by Reynolds, James D

“…The use of anti–vascular endothelial growth factor (anti-VEGF) agents has revolutionized the treatment of certain neovascular ocular conditions including…”
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Urrets-Zavalia syndrome following goniotomy in a child by Chelnis, James G., MD, Sieminski, Sandra F., MD, Reynolds, James D., MD

“…Urrets-Zavalia syndrome is a surgical complication in which the pupil remains fixed and dilated after a procedure. It is believed to be caused by brief periods…”
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Reducing acetylated tau is neuroprotective in brain injury by Shin, Min-Kyoo, Vázquez-Rosa, Edwin, Koh, Yeojung, Dhar, Matasha, Chaubey, Kalyani, Cintrón-Pérez, Coral J., Barker, Sarah, Miller, Emiko, Franke, Kathryn, Noterman, Maria F., Seth, Divya, Allen, Rachael S., Motz, Cara T., Rao, Sriganesh Ramachandra, Skelton, Lara A., Pardue, Machelle T., Fliesler, Steven J., Wang, Chao, Tracy, Tara E., Gan, Li, Liebl, Daniel J., Savarraj, Jude P.J., Torres, Glenda L., Ahnstedt, Hilda, McCullough, Louise D., Kitagawa, Ryan S., Choi, H. Alex, Zhang, Pengyue, Hou, Yuan, Chiang, Chien-Wei, Li, Lang, Ortiz, Francisco, Kilgore, Jessica A., Williams, Noelle S., Whitehair, Victoria C., Gefen, Tamar, Flanagan, Margaret E., Stamler, Jonathan S., Jain, Mukesh K., Kraus, Allison, Cheng, Feixiong, Reynolds, James D., Pieper, Andrew A.

“…Traumatic brain injury (TBI) is the largest non-genetic, non-aging related risk factor for Alzheimer’s disease (AD). We report here that TBI induces tau…”
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Control of tissue oxygenation by S-nitrosohemoglobin in human subjects by Reynolds, James D, Posina, Kanna, Zhu, Lin, Jenkins, Trevor, Matto, Faisal, Hausladen, Alfred, Kashyap, Vikram, Schilz, Robert, Zhang, Rongli, Mannick, Joan, Klickstein, Lloyd, Premont, Richard T, Stamler, Jonathan S

“…S-Nitrosohemoglobin (SNO-Hb) is unique among vasodilators in coupling blood flow to tissue oxygen requirements, thus fulfilling an essential function of the…”
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Letter by Reynolds et al Regarding Article, “Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell” by Reynolds, James D., Premont, Richard T., Stamler, Jonathan S.

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