Search Results - "REX GASKINS, H"

Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes by Amato, Katherine R, Yeoman, Carl J, Kent, Angela, Righini, Nicoletta, Carbonero, Franck, Estrada, Alejandro, Rex Gaskins, H, Stumpf, Rebecca M, Yildirim, Suleyman, Torralba, Manolito, Gillis, Marcus, Wilson, Brenda A, Nelson, Karen E, White, Bryan A, Leigh, Steven R

“…The gastrointestinal (GI) microbiome contributes significantly to host nutrition and health. However, relationships involving GI microbes, their hosts and host…”
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Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells by Shao, Yuxin, Wolf, Patricia G., Guo, Shuangshuang, Guo, Yuming, Gaskins, H. Rex, Zhang, Bingkun

“…Zinc plays an important role in maintaining intestinal barrier function as well as modulating cellular signaling recognition and protein kinase activities. The…”
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Taurocholic acid metabolism by gut microbes and colon cancer by Ridlon, Jason M., Wolf, Patricia G., Gaskins, H. Rex

“…Colorectal cancer (CRC) is one of the most frequent causes of cancer death worldwide and is associated with adoption of a diet high in animal protein and…”
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The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology by Ridlon, Jason M., Daniel, Steven L., Gaskins, H. Rex

“…Bile acids are detergents derived from cholesterol that function to solubilize dietary lipids, remove cholesterol from the body, and act as nutrient signaling…”
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Contributions of the microbial hydrogen economy to colonic homeostasis by Carbonero, Franck, Benefiel, Ann C., Gaskins, H. Rex

“…Colonic gases are integral to digestion, with changes in the volume and composition of these gases linked to bowel disorders. In this Review, the authors…”
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Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans by Ou, Junhai, Carbonero, Franck, Zoetendal, Erwin G, DeLany, James P, Wang, Mei, Newton, Keith, Gaskins, H Rex, O'Keefe, Stephen JD

“…Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota…”
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Gut Microbiome of Coexisting BaAka Pygmies and Bantu Reflects Gradients of Traditional Subsistence Patterns by Gomez, Andres, Petrzelkova, Klara J., Burns, Michael B., Yeoman, Carl J., Amato, Katherine R., Vlckova, Klara, Modry, David, Todd, Angelique, Jost Robinson, Carolyn A., Remis, Melissa J., Torralba, Manolito G., Morton, Elise, Umaña, Juan D., Carbonero, Franck, Gaskins, H. Rex, Nelson, Karen E., Wilson, Brenda A., Stumpf, Rebecca M., White, Bryan A., Leigh, Steven R., Blekhman, Ran

“…To understand how the gut microbiome is impacted by human adaptation to varying environments, we explored gut bacterial communities in the BaAka rainforest…”
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Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice by Allen, Jacob M, Berg Miller, Margret E, Pence, Brandt D, Whitlock, Keith, Nehra, Vandana, Gaskins, H Rex, White, Bryan A, Fryer, John D, Woods, Jeffrey A

“…We have previously shown that voluntary wheel running (VWR) attenuates, whereas forced treadmill running (FTR) exacerbates, intestinal inflammation and…”
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Diversity and distribution of sulfur metabolic genes in the human gut microbiome and their association with colorectal cancer by Wolf, Patricia G, Cowley, Elise S, Breister, Adam, Matatov, Sarah, Lucio, Luke, Polak, Paige, Ridlon, Jason M, Gaskins, H Rex, Anantharaman, Karthik

“…Recent evidence implicates microbial sulfidogenesis as a potential trigger of colorectal cancer (CRC), highlighting the need for comprehensive knowledge of…”
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Gut microbiome composition and metabolomic profiles of wild western lowland gorillas (Gorilla gorilla gorilla) reflect host ecology by Gomez, Andres, Petrzelkova, Klara, Yeoman, Carl J., Vlckova, Klara, Mrázek, Jakub, Koppova, Ingrid, Carbonero, Franck, Ulanov, Alexander, Modry, David, Todd, Angelique, Torralba, Manolito, Nelson, Karen E., Gaskins, H. Rex, Wilson, Brenda, Stumpf, Rebecca M., White, Bryan A., Leigh, Steven R.

“…The metabolic activities of gut microbes significantly influence host physiology; thus, characterizing the forces that modulate this micro‐ecosystem is key to…”
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Galacto-oligosaccharides may directly enhance intestinal barrier function through the modulation of goblet cells by Bhatia, Shikha, Prabhu, P. Nagendra, Benefiel, Ann C., Miller, Michael J., Chow, JoMay, Davis, Steven R., Gaskins, H. Rex

“…Scope Here we have tested the hypothesis that prebiotic galacto‐oligosaccharides (GOS) may enhance mucosal barrier function through direct modulation of goblet…”
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Abundance and diversity of mucosa-associated hydrogenotrophic microbes in the healthy human colon by Nava, Gerardo M, Carbonero, Franck, Croix, Jennifer A, Greenberg, Eugene, Gaskins, H Rex

“…Hydrogenotrophic microbiota have a significant impact on colonic health; however, little is known about their diversity and ecology in situ . Here,…”
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Methods to study the tumor microenvironment under controlled oxygen conditions by Byrne, Matthew B, Leslie, Matthew T, Gaskins, H. Rex, Kenis, Paul J.A

“…Highlights • Hypoxia, low levels of oxygen concentration, affects cell behavior and fate. • Real-time cell behavior studies in hypoxia are difficult with…”
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Pyrosequencing-based analysis of the mucosal microbiota in healthy individuals reveals ubiquitous bacterial groups and micro-heterogeneity by Hong, Pei-Ying, Croix, Jennifer A, Greenberg, Eugene, Gaskins, H Rex, Mackie, Roderick I

“…This study used 16S rRNA-based pyrosequencing to examine the microbial community that is closely associated with the colonic mucosa of five healthy…”
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Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice by Baldwin, Jessie, Collins, Brian, Wolf, Patricia G., Martinez, Kristina, Shen, Wan, Chuang, Chia-Chi, Zhong, Wei, Cooney, Paula, Cockrell, Chase, Chang, Eugene, Gaskins, H. Rex, McIntosh, Michael K.

“…Our objective was to determine if consuming table grapes reduces adiposity and its metabolic consequences and alters gut microbiota in mice fed a high-fat…”
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Completion of the gut microbial epi-bile acid pathway by Doden, Heidi L., Wolf, Patricia G., Gaskins, H. Rex, Anantharaman, Karthik, Alves, João M. P., Ridlon, Jason M.

“…Bile acids are detergent molecules that solubilize dietary lipids and lipid-soluble vitamins. Humans synthesize bile acids with α-orientation hydroxyl groups…”
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The 'in vivo lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice by Ridlon, Jason M., Devendran, Saravanan, Alves, João Mp, Doden, Heidi, Wolf, Patricia G., Pereira, Gabriel V., Ly, Lindsey, Volland, Alyssa, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Chlipala, George E., Green, Stefan J., Hernandez, Alvaro G., Fields, Christopher J., Wright, Christy L., Kakiyama, Genta, Cann, Isaac, Kashyap, Purna, McCracken, Vance, Gaskins, H. Rex

“…The formation of secondary bile acids by gut microbes is a current topic of considerable biomedical interest. However, a detailed understanding of the biology…”
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On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa by Croix, Jennifer A, Carbonero, Franck, Nava, Gerardo M, Russell, Mark, Greenberg, Eugene, Gaskins, H Rex

“…The colonic mucus layer is comprised primarily of acidomucins, which provide viscous properties and can be broadly classified into sialomucins or sulfomucins…”
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Microbial modulation of innate defense : goblet cells and the intestinal mucus layer by DEPLANCKE, Bart, GASKINS, H. Rex

“…The gastrointestinal epithelium is covered by a protective mucus gel composed predominantly of mucin glycoproteins that are synthesized and secreted by goblet…”
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Hydrogen Sulfide Induces Direct Radical-Associated DNA Damage by Attene-Ramos, Matias S., Wagner, Elizabeth D., Gaskins, H. Rex, Plewa, Michael J.

“…Hydrogen sulfide (H 2 S) is produced by indigenous sulfate-reducing bacteria in the large intestine and represents an environmental insult to the colonic…”
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