Search Results - "REUTER, W"
-
1
Prognostic role of docetaxel-induced suppression of free testosterone serum levels in metastatic prostate cancer patients
Published in Scientific reports (12-08-2021)“…To date, only few data concerning the biologically active, free form of testosterone (FT) are available in metastatic prostate cancer (mPC) and the impact of…”
Get full text
Journal Article -
2
Impact of sarcopenia in advanced and metastatic soft tissue sarcoma
Published in International journal of clinical oncology (01-11-2021)“…Introduction Advanced or metastatic soft tissue sarcoma (a/mSTS) is associated with a dismal prognosis. Patient counseling on treatment aggressiveness is…”
Get full text
Journal Article -
3
Pathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury
Published in The Journal of immunology (1950) (01-05-2009)“…Intestinal ischemia-reperfusion (IR) injury is initiated when natural IgM Abs recognize neo-epitopes that are revealed on ischemic cells. The target molecules…”
Get full text
Journal Article -
4
Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck
Published in British journal of cancer (12-02-2007)“…Despite significant advances in the use of surgery, chemotherapy and radiotherapy to treat squamous cell carcinoma of the head and neck (SCCHN), prognosis has…”
Get full text
Journal Article -
5
Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia
Published in Leukemia (01-02-2012)“…To study the prevalence and prognostic importance of mutations in NADH dehydrogenase subunit 4 ( ND4 ), a mitochondrial encoded transmembrane component of the…”
Get full text
Journal Article -
6
Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2012)“…Deregulation of Ras/ERK signaling in myeloid leukemias makes this pathway an interesting target for drug development. Myeloid leukemia cell lines were screened…”
Get full text
Journal Article -
7
Transport of Atmospheric Moisture during Three Extreme Rainfall Events over the Mackenzie River Basin
Published in Journal of hydrometeorology (01-08-2005)“…Lagrangian trajectories were computed for three extreme summer rainfall events (with rainfall exceeding 100 mm) over the southern Mackenzie River basin to test…”
Get full text
Journal Article -
8
Cell-cycle–dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling
Published in Blood (15-03-2001)“…Disruption of the RAS–to–mitogen-activated protein kinase (MAPK/ERK) signaling pathway, either directly through activatingRAS gene mutations or indirectly…”
Get full text
Journal Article -
9
Carboplatin plus weekly docetaxel as salvage chemotherapy in docetaxel-resistant and castration-resistant prostate cancer
Published in World journal of urology (01-06-2010)“…Background There is no proven, effective, standard second-line chemotherapy for castration- and docetaxel-resistant prostate cancer (DRPC). Recent data suggest…”
Get full text
Journal Article -
10
NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia
Published in British journal of haematology (01-06-2013)Get full text
Journal Article -
11
Lack of noncanonical RAS mutations in cytogenetically normal acute myeloid leukemia
Published in Annals of hematology (01-06-2014)“…Transforming mutations in RAS genes are commonly found in human malignancies, including myeloid leukemias. To investigate the incidence, spectrum, and…”
Get full text
Journal Article -
12
Cytokine evaluation in individuals with low back pain using discographic lavage
Published in The spine journal (01-03-2010)“…Abstract Background context The pathophysiology underlying degenerative disc disease and its implication in painful syndromes remain unclear. However, spine…”
Get full text
Journal Article -
13
Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS‐to‐MAP kinase signalling in multiple myeloma cells
Published in British journal of haematology (01-09-2005)“…Summary The high incidence of activating RAS mutations, coupled with accumulating evidence linking RAS to multiple myeloma (MM) pathogenesis, indicate that…”
Get full text
Journal Article -
14
Effects of Weather on Traffic Collisions in Edmonton, Canada
Published in Atmosphere-ocean (20-10-2018)“…Three years of hourly traffic collision data and associated weather data for the city of Edmonton, Alberta, Canada, were analyzed. Using a matched-pair…”
Get full text
Journal Article -
15
Possible role of MDR1 two-locus genotypes for young-age onset ulcerative colitis but not Crohn's disease
Published in European journal of clinical pharmacology (01-10-2007)“…The role of the single nucleotide polymorphisms (SNPs) on positions 2677G>T/A and 3435C>T of the multi-drug-resistance gene 1 (MDR1) in inflammatory bowel…”
Get full text
Journal Article -
16
Molecularly targeted therapies in myelodysplastic syndromes and acute myeloid leukemias
Published in Annals of hematology (01-03-2006)“…Although there has been significant progress in acute myeloid leukemia (AML) treatment in younger adults during the last decade, standard induction therapy…”
Get full text
Journal Article -
17
Fatty acids in colostrum from mothers of children at high risk of atopy in relation to clinical and laboratory signs of allergy in the first year of life
Published in Allergy (Copenhagen) (01-04-2004)“…Background: It remains controversial whether fatty acid (FA) composition of breast milk relates to development of atopy in the infant. This study evaluates FA…”
Get full text
Journal Article -
18
WRF Model Simulation of Two Alberta Flooding Events and the Impact of Topography
Published in Journal of hydrometeorology (01-04-2012)“…This study examines simulations of two flooding events in Alberta, Canada, during June 2005, made using the Weather Research and Forecasting Model (WRF). The…”
Get full text
Journal Article -
19
Therapeutic efficacy of prenylation inhibitors in the treatment of myeloid leukemia
Published in Leukemia (01-08-2003)“…Farnesyltransferase inhibitors (FTIs) represent a new class of anticancer agents that specifically target post-translational farnesylation of various proteins…”
Get full text
Journal Article -
20
Head and neck Merkel cell carcinoma: a ten-year multi-centre review on the South Coast of England
Published in British journal of oral & maxillofacial surgery (01-06-2011)Get full text
Journal Article