Search Results - "REUTER, Michael"
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Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing
Published in Nature (London) (01-12-2011)“…Piwi protein Miwi is shown to be a small RNA-guided RNase in mice; disrupting the catalytic activity of Miwi results in increased accumulation of LINE1…”
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2
Inflammaging impairs peripheral nerve maintenance and regeneration
Published in Aging cell (01-12-2018)“…The regenerative capacity of peripheral nerves declines during aging, contributing to the development of neuropathies, limiting organism function. Changes in…”
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Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile
Published in Nature structural & molecular biology (01-06-2009)“…piRNAs have been implicated in transposon silencing. Tudor domain–containing protein-1 (Tdrd1) is now shown to interact with the mouse Piwi ortholog Mili and…”
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A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing
Published in Molecular cell (28-09-2012)“…Epigenetic silencing of transposons by Piwi-interacting RNAs (piRNAs) constitutes an RNA-based genome defense mechanism. Piwi endonuclease action amplifies the…”
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β2-glycoprotein I, the major target in antiphospholipid syndrome, is a special human complement regulator
Published in Blood (08-09-2011)“…The human plasma protein β2-glycoprotein I (β2-GPI) is the major target of autoantibodies associated with antiphospholipid syndrome. However, the biologic…”
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The TDRD9-MIWI2 Complex Is Essential for piRNA-Mediated Retrotransposon Silencing in the Mouse Male Germline
Published in Developmental cell (01-12-2009)“…Host-defense mechanisms against transposable elements are critical to protect the genome information. Here we show that tudor-domain containing 9 ( Tdrd9) is…”
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PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway
Published in Molecular cell (07-01-2016)“…PIWI-interacting RNAs (piRNAs) guide PIWI proteins to suppress transposons in the cytoplasm and nucleus of animal germ cells, but how silencing in the two…”
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Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2010)“…Piwi-interacting RNAs (piRNAs) are essential for silencing of transposable elements in the germline, but their biogenesis is poorly understood. Here we…”
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Impact of nuclear Piwi elimination on chromatin state in Drosophila melanogaster ovaries
Published in Nucleic acids research (02-06-2014)“…The Piwi-interacting RNA (piRNA)-interacting Piwi protein is involved in transcriptional silencing of transposable elements in ovaries of Drosophila…”
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Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2011)“…In the male germline in mammals, chromatoid bodies, a specialized assembly of cytoplasmic ribonucleoprotein (RNP), are structurally evident during meiosis and…”
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Proteomic analysis of peripheral nerve myelin during murine aging
Published in Frontiers in cellular neuroscience (30-10-2023)“…Aging of the peripheral nervous system (PNS) is associated with structural and functional changes that lead to a reduction in regenerative capacity and the…”
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Recognition of 2′- O-Methylated 3′-End of piRNA by the PAZ Domain of a Piwi Protein
Published in Structure (London) (09-02-2011)“…Piwi proteins are germline-specific Argonautes that associate with small RNAs called Piwi-interacting RNAs (piRNAs), and together with these RNAs are…”
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Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc
Published in RNA (Cambridge) (01-12-2012)“…Piwi-interacting RNAs (piRNAs) are a gonad-specific class of small RNAs that associate with the Piwi clade of Argonaute proteins and play a key role in…”
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Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b
Published in PloS one (11-10-2012)“…Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement…”
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The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b
Published in PLoS pathogens (01-12-2008)“…The Gram-positive bacterium Staphylococcus aureus, similar to other pathogens, binds human complement regulators Factor H and Factor H related protein 1…”
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Reciprocity between electroluminescence and quantum efficiency used for the characterization of silicon solar cells
Published in Progress in photovoltaics (01-09-2009)“…Spectrally and spatially resolved electroluminescence emission of crystalline silicon solar cells is interpreted in terms of two electro‐optical reciprocity…”
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Interstitial lung disease in polymyositis and dermatomyositis: Clinical course and response to treatment
Published in Seminars in arthritis and rheumatism (01-04-2003)“…Objectives: To assess the prevalence, clinical characteristics, and treatment options of patients with interstitial lung disease (ILD) in polymyositis and…”
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Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detection
Published in Radiology (01-05-2003)“…To evaluate the diagnostic accuracy of common magnetic resonance (MR) imaging sequences for detection of small pulmonary nodules by using a chest phantom and…”
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Risk factors for pulmonary barotrauma in divers
Published in Chest (01-09-1997)“…Pulmonary barotrauma (PBT) of ascent is a feared complication in compressed air diving. Although certain respiratory conditions are thought to increase the…”
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Mantid—Data analysis and visualization package for neutron scattering and μ SR experiments
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (11-11-2014)“…The Mantid framework is a software solution developed for the analysis and visualization of neutron scattering and muon spin measurements. The framework is…”
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