Search Results - "REUHL, Kenneth R"

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice by Bose, Mousumi, Lambert, Joshua D, Ju, Jihyeung, Reuhl, Kenneth R, Shapses, Sue A, Yang, Chung S

“…In this study, we investigated the effects of the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), on high-fat-induced obesity, symptoms of…”
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Hepatotoxicity of high oral dose (−)-epigallocatechin-3-gallate in mice by Lambert, Joshua D., Kennett, Mary J., Sang, Shengmin, Reuhl, Kenneth R., Ju, Jihyeung, Yang, Chung S.

“…The tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) has been studied for chronic disease preventive effects, and is marketed as part of many dietary…”
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Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance by Garbuzenko, Olga B, Saad, Maha, Pozharov, Vitaly P, Reuhl, Kenneth R, Mainelis, Gediminas, Minko, Tamara

“…Development of cancer cell resistance, low accumulation of therapeutic drug in the lungs, and severe adverse treatment side effects represent main obstacles to…”
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Effects of Green Tea Polyphenol (−)-Epigallocatechin-3-gallate on Newly Developed High-Fat/Western-Style Diet-Induced Obesity and Metabolic Syndrome in Mice by Chen, Yu-Kuo, Cheung, Connie, Reuhl, Kenneth R, Liu, Anna Ba, Lee, Mao-Jung, Lu, Yao-Ping, Yang, Chung S

“…The aim of this study was to investigate the effects of (−)-epigallocatechin-3-gallate (EGCG) on newly developed high-fat/Western-style diet-induced obesity…”
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Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2 by Ivanova, Vera, Garbuzenko, Olga B., Reuhl, Kenneth R., Reimer, David C., Pozharov, Vitaly P., Minko, Tamara

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and often fatal form of interstitial lung disease. We hypothesized that the local pulmonary…”
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A New Neurobehavioral Model of Autism in Mice: Pre-and Postnatal Exposure to Sodium Valproate by Wagner, George C, Reuhl, Kenneth R, Cheh, Michelle, McRae, Paulette, Halladay, Alycia K

“…Autism symptoms, including impairments in language development, social interactions, and motor skills, have been difficult to model in rodents. Since children…”
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Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine by Lu, Gang, Liao, Jie, Yang, Guangyu, Reuhl, Kenneth R, Hao, Xingpei, Yang, Chung S

“…The present study investigated the inhibitory effects of Polyphenon E [a standardized green tea polyphenol preparation containing 65%…”
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Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells by Teh, Jessica L. F., Shah, Raj, La Cava, Stephanie, Dolfi, Sonia C., Mehta, Madhura S., Kongara, Sameera, Price, Sandy, Ganesan, Shridar, Reuhl, Kenneth R., Hirshfield, Kim M., Karantza, Vassiliki, Chen, Suzie

“…Metabotropic glutamate receptor 1 (mGluR1/Grm1) is a member of the G-protein-coupled receptor superfamily, which was once thought to only participate in…”
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VPA-induced apoptosis and behavioral deficits in neonatal mice by Yochum, Carrie L, Dowling, Peter, Reuhl, Kenneth R, Wagner, George C, Ming, Xue

“…Abstract Sodium valproate (VPA) administered to neonatal mice causes cognitive and motor deficits similar to those observed in humans with autism. In an effort…”
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Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases by Zhang, Min, Garbuzenko, Olga B, Reuhl, Kenneth R, Rodriguez-Rodriguez, Lorna, Minko, Tamara

“…To develop an approach for the effective treatment of ovarian tumor, prevention of metastases and limitation of side effects. In order to combine chemotherapy…”
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Novel Cystine Ester Mimics for the Treatment of Cystinuria-induced Urolithiasis in a Knockout Mouse Model by Sahota, Amrik, Parihar, Jaspreet S, Capaccione, Kathleen M, Yang, Min, Noll, Kelsey, Gordon, Derek, Reimer, David, Yang, Ill, Buckley, Brian T, Polunas, Marianne, Reuhl, Kenneth R, Lewis, Matthew R, Ward, Michael D, Goldfarb, David S, Tischfield, Jay A

“…Objective To assess the effectiveness of l -cystine dimethyl ester (CDME), an inhibitor of cystine crystal growth, for the treatment of cystine urolithiasis in…”
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Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice by Li, Guangxun, Wang, Hong, Liu, Anna B, Cheung, Connie, Reuhl, Kenneth R, Bosland, Maarten C, Yang, Chung S

“…To develop a relevant mouse model for prostate cancer prevention research, we administered a dietary carcinogen,…”
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Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E by Burke, Kelly, Cheng, Yinghong, Li, Baogang, Petrov, Alex, Joshi, Pushkar, Berman, Robert F., Reuhl, Kenneth R., DiCicco-Bloom, Emanuel

“…The developing brain is highly sensitive to methylmercury (MeHg). Still, the initial changes in cell proliferation that may contribute to long-term MeHg…”
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CYP2A13 in Human Respiratory Tissues and Lung Cancers: An Immunohistochemical Study with A New Peptide-Specific Antibody by ZHU, Liang-Ru, THOMAS, Paul E, GANG LU, REUHL, Kenneth R, YANG, Guang-Yu, WANG, Li-Dong, WANG, Shou-Lin, YANG, Chung S, HE, Xiao-Yang, HONG, Jun-Yan

“…Human cytochrome P450 2A13 (CYP2A13) is highly efficient in the metabolic activation of a tobacco-specific carcinogen,…”
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Inflammatory Response and Glutathione Peroxidase in a Model of Stroke by Ishibashi, Nobuya, Prokopenko, Olga, Reuhl, Kenneth R, Mirochnitchenko, Oleg

“…Stroke is one of the leading causes of death in major industrial countries. Many factors contribute to the cellular damage resulting from ischemia/reperfusion…”
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Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s) by Garbuzenko, O.B, Ivanova, V, Kholodovych, V, Reimer, D.C, Reuhl, K.R, Yurkow, E, Adler, D, Minko, T

“…Abstract Inhalation delivery of prostaglandin E (PGE2) in combination with selected siRNA(s) was proposed for the efficient treatment of idiopathic pulmonary…”
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Mechanisms of Injury in the Central Nervous System by Philbert, Martin A., Billingsley, Melvin L., Reuhl, Kenneth R.

“…Neurotoxicants with similar structural features or common mechanisms of chemical action frequently produce widely divergent neuropathologic outcomes…”
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U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo by Goraczniak, Rafal, Wall, Brian A, Behlke, Mark A, Lennox, Kim A, Ho, Eric S, Zaphiros, Nikolas H, Jakubowski, Christopher, Patel, Neil R, Zhao, Steven, Magaway, Carlo, Subbie, Stacey A, Jenny Yu, Lumeng, LaCava, Stephanie, Reuhl, Kenneth R, Chen, Suzie, Gunderson, Samuel I

“…U1 Adaptor is a recently discovered oligonucleotide-based gene-silencing technology with a unique mechanism of action that targets nuclear pre-mRNA processing…”
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Effective Intravenous Therapy for Neurodegenerative Disease With a Therapeutic Enzyme and a Peptide That Mediates Delivery to the Brain by Meng, Yu, Sohar, Istvan, Sleat, David E, Richardson, Jason R, Reuhl, Kenneth R, Jenkins, Robert B, Sarkar, Gobinda, Lobel, Peter

“…The blood–brain barrier (BBB) presents a major challenge to effective treatment of neurological disorders, including lysosomal storage diseases (LSDs), which…”
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Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat by Mesia-Vela, Sonia, Sanchez, Rosa I, Reuhl, Kenneth R, Conney, Allan H, Kauffman, Frederick C

“…Exposure of female August-Copenhagen Irish (ACI) rats for 28 weeks to 3 mg of estradiol (E(2)) contained in cholesterol pellets elevated blood E(2) levels and…”
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