Search Results - "RETEL, J"

The economic lot-sizing problem with an emission capacity constraint by Retel Helmrich, Mathijn J., Jans, Raf, van den Heuvel, Wilco, Wagelmans, Albert P.M.

“…•We consider a lot-sizing problem with one global constraint on carbon emissions.•We show that this problem is NP-hard.•We present a Lagrangian heuristic,…”
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Economic lot-sizing with remanufacturing: complexity and efficient formulations by Retel Helmrich, Mathijn J., Jans, Raf, van den Heuvel, Wilco, Wagelmans, Albert P.M.

“…Within the framework of reverse logistics, the classic economic lot-sizing problem has been extended with a remanufacturing option. In this extended problem,…”
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Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation by Mans, D R, Lafleur, M V, Westmijze, E J, Horn, I R, Bets, D, Schuurhuis, G J, Lankelma, J, Retèl, J

“…Etoposide [4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta- D-glucopyranoside)] can be metabolized to DNA-inactivating catechol, ortho-quinone and…”
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Influence of the antioxidant N-acetylcysteine and its metabolites on damage induced by bleomycin in PM2 bacteriophage DNA by Cloos, Jacqueline, Gille, Johan J.P., Steen, Ivar, Lafleur, M.Vincent, Retèl, Jan, Snow, Gordon B., Braakhuis, Boudewijn J.M.

“…Bleomycin is considered to be a useful model compound for studying environmental carcinogenesis, due to its broad spectrum of DNA damaging properties. In…”
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Biological consequences of DNA damage introduced in bacteriophage PM2 DNA by hydrogen peroxide-mediated free radical reactions by GILLE, J. J. P, WIENTJES, N. M, LAFLEUR, M. V. M, JOENJE, H, RETEL, J

“…In order to study the biological consequences of DNA damage induced by H2O2-mediated free radical reactions, DNA from bacteriophage PM2 was exposed to H2O2,…”
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Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213) by Mans, D R, Lafleur, M V, Westmijze, E J, van Maanen, J M, van Schaik, M A, Lankelma, J, Retèl, J

“…In this report, the types of DNA damage introduced by the ortho-quinone and the semiquinone free radical of…”
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Mechanism of action of antitumor drug etoposide: a review by van Maanen, J M, Retèl, J, de Vries, J, Pinedo, H M

“…Metabolism studies of the antitumor drug etoposide show the formation of metabolites in the lactone ring, which are probably not important for the drug's…”
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Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213) by VAN MAANEN, J. M. S, DE VRIES, J, PAPPIE, D, VAN DEN AKKER, E, LAFLEUR, M. V. M, RETEL, J, VAN DER GREEF, J, PINEDO, H. M

“…The antitumor agent VP-16-213 is oxidatively O-demethylated by rat liver microsomes and purified rat liver microsomal cytochrome P-450. 3-Methylcholanthrene…”
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Mutational specificity of gamma-rays differs for the same target in plasmid DNA and double-stranded (RF) M13 bacteriophage DNA by Hoebee, B, Loman, H, Brouwer, J, Retèl, J

“…In the lacZ alpha gene of a pUC plasmid a 144 bp insert was cloned as target for mutagenesis. Irradiation of the plasmid in a diluted aqueous solution by 60Co…”
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An optical study of the conformation of the aminofluorene-DNA complex by van Houte, L P, Bokma, J T, Lutgerink, J T, Westra, J G, Retèl, J, van Grondelle, R, Blok, J

“…Calf thymus DNA was modified with 2-aminofluorene (AF) to different extents by treatment with N-hydroxy-2-aminofluorene. The AF-modified DNAs together with…”
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60Co γ-rays induce predominantly C/G to G/C transversions in double-stranded M13 DNA by HOEBEE, B, BROUWER, J, VAN DE PUTTE, P, LOMAN, H, RETEL, J

“…Upon irradiation with gamma rays of an oxygenated aqueous solution of double-stranded M13 DNA, a very specific mutation spectrum was found with respect to both…”
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Effects of the ortho-quinone and catechol of the antitumor drug VP-16-213 on the biological activity of single-stranded and double-stranded phi X174 DNA by van Maanen, J M, Lafleur, M V, Mans, D R, van den Akker, E, de Ruiter, C, Kootstra, P R, Pappie, D, de Vries, J, Retèl, J, Pinedo, H M

“…We have studied the effects of the recently reported two new metabolites of the antitumor agent VP-16-213, the ortho-dihydroxy derivative or catechol and the…”
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Excited state properties of the N-(deoxyguanosin-8-yl)-2-aminofluorene adducts by van Houte, L P, van Grondelle, R, Retèl, J, Westra, J G, Zinger, D, Sutherland, J C, Kim, S K, Geacintov, N E

“…The spectroscopic characteristics of adducts derived from the covalent binding of the carcinogen 2-aminofluorene to the C8 position of deoxyguanosine…”
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Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA by MANS, D. R. A, RETEL, J, VAN MAANEN, J. M. S, LAFLEUR, M. V. M, VAN SCHAIK, M. A, PINEDO, H. M, LANKELMA, J

“…The mechanism of action of the anti-tumour agent etoposide (VP-16-213) could involve its bioactivation to metabolites which can damage DNA. Active metabolites…”
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Interaction of singlet oxygen with DNA and biological consequences by Lutgerink, J T, van den Akker, E, Smeets, I, Pachen, D, van Dijk, P, Aubry, J M, Joenje, H, Lafleur, M V, Retèl, J

“…To study the interaction of singlet oxygen (1O2) with DNA and the biological consequences of 1O2-induced DNA damage, we used the thermodissociable endoperoxide…”
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Inactivation and repair of double-stranded DNA damaged by the aziridinyl nitroimidazole RSU 1069 by Lafleur, M V, Westmijze, E J, Visser, O J, Wagenaar, N, Soetekouw, R, Loman, H, Retel, J

“…Incubation of RSU 1069 in the presence of biologically active double-stranded phi X174 DNA resulted in, depending on pH, ionic strength and concentration of…”
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Topographical analysis of yeast ribosomal DNA by cleavage with restriction endonucleases. II. The physical map of EcoRI fragments by Meyerink, Jan H., Jan, Retèl

“…Yeast ribosomal DNA (rDNA) was digested with the restriction endonuclease EcoRI. Eight distinct fragments were obtained with a molecular weight of 4.35 (1),…”
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Transcription specificity of yeast RNA polymerase A. highly specific transcription in vitro of the homologous ribosomal transcription units by Van Keulen, H, Retel, J

“…In order to establish more extensively the transcription specificity in vitro of yeast RNA polymerase A, both heterologous DNA's (T7 DNA, linear and circular…”
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Mutational specificity of oxidative DNA damage by Retèl, J, Hoebee, B, Braun, J E, Lutgerink, J T, van den Akker, E, Wanamarta, A H, Joenje, H, Lafleur, M V

“…In this paper we describe our studies on the mutagenic consequences of oxidative DNA damage introduced by radiation-induced OH radicals (.OH) and by exposure…”
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Characterization of Yeast Ribosomal DNA by RETÈL, Jan, KEULEN, Harry

“…High‐molecular‐weight yeast ribosomal DNA, purified by preparative Hg2/Cs2SO4 gradient centrifugation, was characterized using RNA‐DNA hybridization, CsCl…”
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