Search Results - "REPINE, John E"
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Nasopharyngeal Type-I Interferon for Immediately Available Prophylaxis Against Emerging Respiratory Viral Infections
Published in Frontiers in immunology (19-05-2021)“…In addition to SARS-CoV-2 and its variants, emerging viruses that cause respiratory viral infections will continue to arise. Increasing evidence suggests a…”
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Effect of ergothioneine on acute lung injury and inflammation in cytokine insufflated rats
Published in Preventive medicine (01-05-2012)“…Abstract Objective The Acute Respiratory Distress Syndrome (ARDS), the most severe form of Acute Lung Injury (ALI), is a highly-fatal, diffuse non-cardiogenic…”
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L-ergothioneine reduces nitration of lactoferrin and loss of antibacterial activity associated with nitrosative stress
Published in Biochemistry and biophysics reports (01-07-2023)“…Lactoferrin (LF) is a multifunctional antimicrobial, anti-inflammatory, and antioxidant protein that occurs naturally in mammals, most notably in exocrine…”
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COUNTERPOINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? No
Published in Chest (01-02-2016)Get full text
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5
Chronic inflammatory diseases and the Acute Respiratory Distress Syndrome (ARDS)
Published in Current pharmaceutical design (2014)“…The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of…”
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6
Rebuttal From Drs Christopher and Repine
Published in Chest (01-02-2016)Get full text
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Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats
Published in PloS one (06-07-2015)“…Glutamine (GLN) attenuates acute lung injury (ALI) but its effect on alveolar macrophages is unknown. We hypothesized that GLN pretreatment would induce the…”
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Functional benefits of ergothioneine and fruit- and vegetable-derived nutraceuticals: Overview of the supplemental issue contents
Published in Preventive medicine (01-05-2012)“…Abstract For good reason, there is increasing interest in assessing the clinical efficacy of dietary supplements, naturally occurring compounds, and…”
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Oxidative stress in chronic obstructive pulmonary disease
Published in American journal of respiratory and critical care medicine (01-08-1997)Get full text
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Neutrophil elastase and acute lung injury: Prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics
Published in Critical care medicine (01-05-2002)“…OBJECTIVESTo review the evidence and rationale that suggest that neutrophil elastase (NE) may contribute to the development of acute lung injury (ALI) and the…”
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Mononuclear Phagocyte Xanthine Oxidoreductase Contributes to Cytokine-Induced Acute Lung Injury
Published in American journal of respiratory cell and molecular biology (01-04-2004)“…Acute lung injury (ALI) is characterized by increased alveolar cytokines, inflammatory cell infiltration, oxidative stress, and alveolar cell apoptosis…”
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Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation
Published in Annals of surgery (01-12-2019)“…OBJECTIVE:To derive and validate a prediction model for the development of ARDS in burn-injured patients. SUMMARY BACKGROUND DATA:Burn injury carries the…”
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Effects of fine carbonaceous particles containing high and low unpaired electron spin densities on lungs of female mice
Published in Translational research : the journal of laboratory and clinical medicine (01-10-2008)“…The negative impacts on human health that accompany inhalation of atmospheric particles are documented in numerous epidemiologic studies, but the effect of…”
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Perioperative lung protective ventilation in obese patients
Published in BMC anesthesiology (06-05-2015)“…The perioperative use and relevance of protective ventilation in surgical patients is being increasingly recognized. Obesity poses particular challenges to…”
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Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure
Published in Analytical and bioanalytical chemistry (01-02-2018)“…Lactoferrin (LF) is an important multifunctional protein that comprises a large fraction of the protein mass in certain human fluids and tissues, and its…”
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Early Effect of Tidal Volume on Lung Injury Biomarkers in Surgical Patients with Healthy Lungs
Published in Anesthesiology (Philadelphia) (01-09-2014)“…The early biological impact of short-term mechanical ventilation on healthy lungs is unknown. The authors aimed to characterize the immediate tidal volume…”
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Depressed prostaglandins and leukotrienes in veterans with Gulf War illness
Published in Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes (03-08-2019)“…Background: There is need to understand biological markers and mechanisms in Gulf War illness (GWI). Goal: To examine whether and how eicosanoids -…”
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Inhalation of two putative Gulf War toxins by mice
Published in Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes (02-06-2016)“…We employed our inhalation methodology to examine whether biomarkers of inflammation and oxidative stress would be produced in mice following inhalation of…”
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Early Increase in Alveolar Macrophage Prostaglandin 15d-PGJ2 Precedes Neutrophil Recruitment into Lungs of Cytokine-Insufflated Rats
Published in Inflammation (01-10-2013)“…ABSTRACT Early detection and prevention is an important goal in acute respiratory distress syndrome research. We determined the concentration of the…”
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Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome : Time for a reevaluation
Published in Critical care medicine (2000)“…Definitions for sepsis, septic shock, acute lung injury (ALI), and acute respiratory distress syndrome (ARDS) were developed by consensus conferences with the…”
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