Search Results - "REOME, Joyce B"

Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge by Hamada, Hiromasa, Garcia-Hernandez, Maria de la Luz, Reome, Joyce B, Misra, Sara K, Strutt, Tara M, McKinstry, Kai K, Cooper, Andrea M, Swain, Susan L, Dutton, Richard W

“…We show here that IL-17-secreting CD4 T (Th)17 and CD8 T (Tc)17 effector cells are found in the lung following primary challenge with influenza A and that…”
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Adoptive Transfer of Tumor-Specific Tc17 Effector T Cells Controls the Growth of B16 Melanoma in Mice by Garcia-Hernandez, Maria de la Luz, Hamada, Hiromasa, Reome, Joyce B, Misra, Sara K, Tighe, Michael P, Dutton, Richard W

“…In vitro generated OVA-specific IL-17-producing CD8 T effector cells (Tc17) from OT-1 mice, adoptively transferred into B16-OVA tumor-bearing mice, controlled…”
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Type 1 and type 2 tumor infiltrating effector cell subpopulations in progressive breast cancer by Reome, Joyce B, Hylind, James C, Dutton, Richard W, Dobrzanski, Mark J

“…Effector T cells fall into two subpopulations based on cytokine-secretion. Type 1 cells secrete IFN-γ, whereas type 2 cells secrete IL-4, IL-10, and GM-CSF…”
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CD8-Mediated Type 1 Antitumor Responses Selectively Modulate Endogenous Differentiated and Nondifferentiated T Cell Localization, Activation, and Function in Progressive Breast Cancer by Dobrzanski, Mark J, Reome, Joyce B, Hylind, James C, Rewers-Felkins, Kathleen A

“…CD8 T cell-mediated immune responses fall into two distinct types based on effector cell-derived cytokine production. Type I CD8 T cells (Tc1) produce…”
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Tc1 and Tc2 Effector Cell Therapy Elicit Long-Term Tumor Immunity by Contrasting Mechanisms That Result in Complementary Endogenous Type 1 Antitumor Responses by Dobrzanski, Mark J, Reome, Joyce B, Hollenbaugh, Joseph A, Dutton, Richard W

“…Cytolytic CD8(+) effector cells fall into two subpopulations based on cytokine secretion. Type 1 CD8(+) T cells (Tc1) secrete IFN-gamma, whereas type 2 CD8(+)…”
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In Vivo Persistence of CD8 Polarized T Cell Subsets Producing Type 1 or Type 2 Cytokines by Cerwenka, Adelheid, Carter, Laura L, Reome, Joyce B, Swain, Susan L, Dutton, Richard W

“…Naive CD8 T cells can be polarized into effectors producing the type 1 cytokines IFN-gamma and IL-2 or the type 2 cytokines IL-4, IL-5, and IL-10,…”
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Therapeutic Effects of Tumor-Reactive Type 1 and Type 2 CD8+ T Cell Subpopulations in Established Pulmonary Metastases by Dobrzanski, Mark J, Reome, Joyce B, Dutton, Richard W

“…Cytolytic CD8+ T cells fall into two subpopulations based on cytokine-secretion. Type 1 CD8+ cells (Tc1) characteristically secrete IFN-gamma, whereas type 2…”
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Type 1 and Type 2 CD8+ Effector T Cell Subpopulations Promote Long-Term Tumor Immunity and Protection to Progressively Growing Tumor by Dobrzanski, Mark J, Reome, Joyce B, Dutton, Richard W

“…Cytolytic CD8+ effector cells fall into two subpopulations based on cytokine secretion. Type 1 CD8+ T cells (Tc1) secrete IFN-gamma, whereas type 2 CD8+ T…”
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Ag-specific type 1 CD8 effector cells enhance methotrexate-mediated antitumor responses by modulating differentiated T cell localization, activation and chemokine production in established breast cancer by Dobrzanski, Mark J, Reome, Joyce B, Hylind, James C, Rewers-Felkins, Kathleen A, Abulsamad, Khaliquzzaman, Adams, Shawna L

“…Abstract The chemotherapeutic agent methotrexate is widely used in the treatment of breast cancer. Although its mechanism-of-action has been defined, less is…”
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Effector cell-derived lymphotoxin alpha and Fas ligand, but not perforin, promote Tc1 and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases by Dobrzanski, Mark J, Reome, Joyce B, Hollenbaugh, Joseph A, Hylind, James C, Dutton, Richard W

“…Cytolytic CD8(+) effector cells fall into two subpopulations based on cytokine secretion. Type 1 CD8(+) T cells (Tc1) secrete IFN-gamma, whereas type 2 CD8(+)…”
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Immunopotentiating Role of IFN-γ in Early and Late Stages of Type 1 CD8 Effector Cell-Mediated Tumor Rejection by Dobrzanski, Mark J., Reome, Joyce B., Dutton, Richard W.

“…Type 1 cytolytic CD8 effector T cells (Tc1) characteristically secrete IFN-γ. Using an OVA-transfected B16 melanoma lung tumor model, we show that OVA…”
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Role of Effector Cell-Derived IL-4, IL-5, and Perforin in Early and Late Stages of Type 2 CD8 Effector Cell-Mediated Tumor Rejection by Dobrzanski, Mark J, Reome, Joyce B, Dutton, Richard W

“…Type 2 CD8 T cells (Tc2) secrete IL-4 and IL-5 and display perforin-dependent cytolysis in vitro. Using an OVA-transfected B16-melanoma model, we show that…”
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Ag-Specific Type 1 CD8 Effector Cells Enhance Methotrexate-Mediated Antitumor Responses by Modulating Endogenous CD49b-Expressing CD4 and CD8 T Effector Cell Subpopulations Producing IL-10 by Dobrzanski, Mark J., Reome, Joyce B., Hylind, James C., Rewers-Felkins, Kathleen A., Abdulsamad, Khaliquzzaman, Adams, Shawna L.

“…The chemotherapeutic agent methotrexate is widely used in the treatment of breast cancer. Although its mechanism-of-action has been defined, less is known…”
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The Effects of Prolonged Administration of 5-Bromodeoxyuridine on Cells of the Immune System by Reome, Joyce B, Johnston, Darrin S, Helmich, Brian K, Morgan, Tammy M, Dutton-Swain, Nicholas, Dutton, Richard W

“…We have determined the in vivo effect of 5-bromodeoxyuridine (BrdU) administered to mice in the drinking water for various lengths of time on the performance…”
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The mechanism of protection against influenza by transfer of Tc17, an IL-17 secreting CD8 T cell subset. (46.5) by Hamada, Hiromasa, Garcia-Hernandez, Maria de la Luz, Reome, Joyce B., Misra, Sara K., Dutton, Richard W.

“…Interleukin (IL) -17 secreting CD4 T (Th)17 and CD8 T (Tc)17 effector cells are found in the lung following primary challenge with influenza A and blocking…”
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Tc17, a new subset of CD8 T cells by Hamada, Hiromasa, Reome, Joyce B., Misra, Sara K., McKinstry, Kai K., Strutt, Tara M., Swain, Susan L., Dutton, Richard W.

“…IL‐17 producing CD4+ (Th17) and CD8+ (Tc17) effector cells are found in the lung following both primary and secondary challenge with influenza A. Tc17…”
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Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge1 by Hamada, Hiromasa, de la Luz Garcia-Hernandez, Maria, Reome, Joyce B., Misra, Sara K., Strutt, Tara M., McKinstry, Kai K., Cooper, Andrea M., Swain, Susan L., Dutton, Richard W.

“…We show here that IL-17-secreting CD4 T (Th)17 and CD8 T (Tc)17 effector cells are found in the lung following primary challenge with influenza A and that…”
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Effector cell-derived lymphotoxin a and Fas ligand, but not perforin, promote Tcl and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases by DOBRZANSKI, Mark J, REOME, Joyce B, HOLLENBAUGH, Joseph A, HYLIND, James C, DUTTON, Richard W

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