Search Results - "RENDAHL, Katherine G"

PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies by Sheng, Qing, D'Alessio, Joseph A, Menezes, Daniel L, Karim, Christopher, Tang, Yan, Tam, Angela, Clark, Suzanna, Ying, Chi, Connor, Anu, Mansfield, Keith G, Rondeau, Jean-Michel, Ghoddusi, Majid, Geyer, Felipe C, Gu, Jane, McLaughlin, Margaret E, Newcombe, Rick, Elliot, GiNell, Tschantz, William R, Lehmann, Sylvie, Fanton, Christie P, Miller, Kathy, Huber, Thomas, Rendahl, Katherine G, Jeffry, Ursula, Pryer, Nancy K, Lees, Emma, Kwon, Paul, Abraham, Judith A, Damiano, Jason S, Abrams, Tinya J

“…The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast,…”
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CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo by TSE, Archie N, RENDAHL, Katherine G, HIBNER, Barbara, GESNER, Thomas G, SCHWARTZ, Gary K, SHEIKH, Tahir, CHEEMA, Haider, AARDALEN, Kim, EMBRY, Millicent, MA, Sylvia, MOLER, Edward J, ZHI JIE NI, LOPES DE MENEZES, Daniel E

“…Purpose: Chk1 kinase is a critical regulator of both S and G 2 -M phase cell cycle checkpoints in response to DNA damage. This study aimed to evaluate the…”
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Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury by Sapieha, Przemyslaw S, Peltier, Martin, Rendahl, Katherine G, Manning, William C, Di Polo, Adriana

“…Basic fibroblast growth factor (or FGF-2) has been shown to be a potent stimulator of retinal ganglion cell (RGC) axonal growth during development. Here we…”
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CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice by XIAOHUA XIN, ABRAMS, Tinya J, TRUDEL, Suzanne, JALLAL, Bahija, MENDEL, Dirk B, HEISE, Carla C, HOLLENBACH, Paul W, RENDAHL, Katherine G, YAN TANG, OEI, Yoko A, EMBRY, Millicent G, SWINARSKI, Debbie E, GARRETT, Evelyn N, PRYER, Nancy K

“…Purpose: The ectopically expressed and deregulated fibroblast growth factor receptor 3 (FGFR3) results from a t(4;14) chromosomal translocation that occurs in…”
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Neutralization of prolactin receptor function by monoclonal antibody LFA102, a novel potential therapeutic for the treatment of breast cancer by Damiano, Jason S, Rendahl, Katherine G, Karim, Christopher, Embry, Millicent G, Ghoddusi, Majid, Holash, Jocelyn, Fanidi, Abdallah, Abrams, Tinya J, Abraham, Judith A

“…Numerous lines of evidence suggest that the polypeptide hormone prolactin (PRL) may contribute to breast and prostate tumorigenesis through its interactions…”
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Two Animal Models of Retinal Degeneration Are Rescued by Recombinant Adeno-associated Virus-Mediated Production of FGF-5 and FGF-18 by Green, Eric S., Rendahl, Katherine G., Zhou, Shangzhen, Ladner, Martha, Coyne, Mazie, Srivastava, Ranjana, Manning, William C., Flannery, John G.

“…The goal of these experiments was to evaluate the potential of the fibroblast growth factor family members FGF-5 and FGF-18 to rescue photoreceptors from cell…”
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AAV-Mediated Expression of Vascular Endothelial Growth Factor Induces Choroidal Neovascularization in Rat by Wang, Fei, Rendahl, Katherine G, Manning, William C, Quiroz, Dulce, Coyne, Mazie, Miller, Sheldon S

“…To develop a small-animal model of choroidal neovascularization (CNV) by injecting adeno-associated virus (AAV)-VEGF into the subretinal space (SRS) of rats…”
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Regulation of gene expression in vivo following transduction by two separate rAAV vectors by Rendahl, Katherine G, Leff, Stuart E, Otten, Gillis R, Spratt, S. Kaye, Bohl, Delphine, Van Roey, Melinda, Donahue, Brian A, Cohen, Lawrence K, Mandel, Ronald J, Danos, Olivier, Snyder, Richard O

“…Control of gene expression is important to gene therapy for purposes of both dosing and safety. In vivo regulation of gene expression was demonstrated…”
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Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors by Rendahl, Katherine G, Quiroz, Dulce, Ladner, Martha, Coyne, Mazie, Seltzer, Jon, Manning, William C, Escobedo, Jaime A

“…Recombinant adeno-associated viral (rAAV) vectors containing an improved tetracycline (tet) system of transcriptional regulation are an efficient strategy for…”
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Retinal Degeneration Is Slowed in Transgenic Rats by AAV-Mediated Delivery of FGF-2 by Lau, Dana, McGee, Laura H, Zhou, Shangzhen, Rendahl, Katherine G, Manning, William C, Escobedo, Jaime A, Flannery, John G

“…We evaluated adeno-associated virus (AAV)-mediated gene transfer of basic fibroblast growth factor (FGF-2) as a therapy for photoreceptor degeneration in a…”
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In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase by LEFF, S. E, RENDAHL, K. G, SPRATT, S. K, KANG, U. J, MANDEL, R. J

“…To investigate the biochemical requirements for in vivo L-DOPA production by cells genetically modified ex vivo in a rat model of Parkinson's disease (PD), rat…”
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In VivoL-DOPA Production by Genetically Modified Primary Rat Fibroblast or 9L Gliosarcoma Cell Grafts via Coexpression of GTPcyclohydrolase I with Tyrosine Hydroxylase by Leff, Stuart E., Rendahl, Katherine G., Spratt, S.Kaye, Kang, Un J., Mandel, Ronald J.

“…To investigate the biochemical requirements forin vivoL-DOPA production by cells genetically modifiedex vivoin a rat model of Parkinson's disease (PD), rat…”
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Defects in courtship and vision caused by amino acid substitutions in a putative RNA-binding protein encoded by the no-on-transient A (nonA) gene of Drosophila by Rendahl, KG, Gaukhshteyn, N, Wheeler, DA, Fry, TA, Hall, JC

“…The Drosophila no-on-transient A (nonA) gene is involved in the visual behaviors and courtship song of the fly. The NONA polypeptide contains two copies of the…”
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Genetic and molecular analysis of the X chromosomal region 14B17-14C4 in Drosophila melanogaster: loss of function in NONA, a nuclear protein common to many cell types, results in specific physiological and behavioral defects by Stanewsky, R, Rendahl, K.G, Dill, M, Saumweber, H

“…We have performed a genetic analysis of the 14C region of the X chromosome of Drosophila melanogaster to isolate loss of function alleles of no-on-transient A…”
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Temporally manipulated rescue of visual and courtship abnormalities caused by a nonA mutation in Drosophila by Rendahl, K G, Hall, J C

“…The no-on-transient-A gene was identified by independently isolated mutations causing visual-response abnormalities or courtship song defects. The nonA(diss)…”
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