Search Results - "REITER, Yoram"
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Functional Specializations of Human Epidermal Langerhans Cells and CD14 + Dermal Dendritic Cells
Published in Immunity (Cambridge, Mass.) (19-09-2008)“…Little is known about the functional differences between the human skin myeloid dendritic cell (DC) subsets, epidermal CD207 + Langerhans cells (LCs) and…”
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2
A novel host-proteome signature for distinguishing between acute bacterial and viral infections
Published in PloS one (18-03-2015)“…Bacterial and viral infections are often clinically indistinguishable, leading to inappropriate patient management and antibiotic misuse. Bacterial-induced…”
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3
The Intracellular Proteome as a Source for Novel Targets in CAR-T and T-Cell Engagers-Based Immunotherapy
Published in Cells (Basel, Switzerland) (21-12-2022)“…The impressive clinical success of cancer immunotherapy has motivated the continued search for new targets that may serve to guide potent effector functions in…”
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4
Multi-center nationwide comparison of seven serology assays reveals a SARS-CoV-2 non-responding seronegative subpopulation
Published in EClinicalMedicine (01-12-2020)“…An Israeli national taskforce performed a multi-center clinical and analytical validation of seven serology assays to determine their utility and limitations…”
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SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors
Published in Toxins (14-11-2018)“…SS1P is an anti-mesothelin immunotoxin composed of a targeting antibody fragment genetically fused to a truncated fragment of Pseudomonas exotoxin A. Delayed…”
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HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis
Published in The Journal of immunology (1950) (01-05-2014)“…CD74, the cell-surface form of the MHC class II invariant chain, is a key inflammatory factor that is involved in various immune-mediated diseases as part of…”
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The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation
Published in The Journal of experimental medicine (14-05-2007)“…CD1d-restricted lymphocytes recognize a broad lipid range. However, how CD1d-restricted lymphocytes translate T cell receptor (TCR) recognition of lipids with…”
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Immunoglobulin-like transcript receptors on human dermal CD14⁺ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming
Published in Proceedings of the National Academy of Sciences - PNAS (13-11-2012)“…Human Langerhans cells (LCs) are highly efficient at priming cytolytic CD8 ⁺ T cells compared with dermal CD14 ⁺ dendritic cells (DCs). Here we show that…”
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T-Cell Receptor-Like Antibodies: Targeting the Intracellular Proteome Therapeutic Potential and Clinical Applications
Published in Antibodies (Basel) (01-09-2013)“…Major histocompatibility complex (MHC) class I molecules are key in the immune response against malignant cells by shaping the T-cell repertoire and presenting…”
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Journal Article Book Review -
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Cutting Edge: MHC Class I-Ly49 Interaction Regulates Neuronal Function
Published in The Journal of immunology (1950) (15-05-2008)“…MHC class I molecules (MHC-I) have been implicated in nervous system development in the mouse. In this study we present evidence for the interaction of MHC-I…”
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Antibodies and their fragments as anti-cancer agents
Published in Current pharmaceutical design (2006)“…The recent developments in the field of recombinant DNA, protein engineering and cancer biology, have let us gain insight into many cancer-related mechanisms…”
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Recombinant immunotoxins in targeted cancer cell therapy
Published in Advances in Cancer Research (2001)“…Targeted cancer therapy in general and immunotherapy in particular combines rational drug design with the progress in understanding cancer biology. This…”
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Book Chapter Journal Article -
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Antibody Molecules Discriminate between Crystalline Facets of a Gallium Arsenide Semiconductor
Published in Nano letters (01-09-2006)“…Seamless integration of biomolecules with manmade materials will most likely rely on molecular recognition and specific binding. In the following we show that…”
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The influence of a human embryonic stem cell-derived microenvironment on targeting of human solid tumor xenografts
Published in Cancer research (Chicago, Ill.) (01-04-2006)“…The awareness of the important role that the surrounding tissue microenvironment and stromal response play in the process of tumorigenesis has grown as a…”
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Direct Visualization of Distinct T Cell Epitopes Derived from a Melanoma Tumor-Associated Antigen by Using Human Recombinant Antibodies with MHC-Restricted T Cell Receptor-like Specificity
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2002)“…Specificity in the cellular immune system is controlled and regulated by the T cell antigen receptor (TCR), which specifically recognizes peptide/major…”
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Efficiency of peptide presentation by dendritic cells compared with other cell types: implications for cross-priming
Published in International immunology (01-12-2006)“…Dendritic cells (DCs) play a key role in the induction of cellular immune responses by harvesting antigens from peripheral tissue for cross-priming CD8+ T…”
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Direct Phenotypic Analysis of Human MHC Class I Antigen Presentation: Visualization, Quantitation, and In Situ Detection of Human Viral Epitopes Using Peptide-Specific, MHC-Restricted Human Recombinant Antibodies
Published in The Journal of immunology (1950) (15-04-2003)“…The advent in recent years of the application of tetrameric arrays of class I peptide-MHC complexes now enables us to detect and study rare populations of…”
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Predicting and controlling the reactivity of immune cell populations against cancer
Published in Molecular systems biology (28-04-2009)“…Heterogeneous cell populations form an interconnected network that determine their collective output. One example of such a heterogeneous immune population is…”
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Tumor-Specific Ab-Mediated Targeting of MHC-Peptide Complexes Induces Regression of Human Tumor Xenografts in Vivo
Published in Proceedings of the National Academy of Sciences - PNAS (15-06-2004)“…A cancer immunotherapy strategy is described herein that combines the advantage of the well established tumor targeting capabilities of high-affinity…”
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Vascular endothelial cells have impaired capacity to present immunodominant, antigenic peptides: a mechanism of cell type-specific immune escape
Published in The Journal of immunology (1950) (15-02-2005)“…Vascular endothelial cells (EC) are an exposed target tissue in the course of CTL-mediated alloimmune diseases such as graft-vs-host disease (GVHD) or solid…”
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