Search Results - "REINKE, N"

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies by Broadhurst, David, Goodacre, Royston, Reinke, Stacey N., Kuligowski, Julia, Wilson, Ian D., Lewis, Matthew R., Dunn, Warwick B.

“…Background Quality assurance (QA) and quality control (QC) are two quality management processes that are integral to the success of metabolomics including…”
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The application of artificial neural networks in metabolomics: a historical perspective by Mendez, Kevin M., Broadhurst, David I., Reinke, Stacey N.

“…Background Metabolomics data, with its complex covariance structure, is typically modelled by projection-based machine learning (ML) methods such as partial…”
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Fecal sample collection methods and time of day impact microbiome composition and short chain fatty acid concentrations by Jones, Jacquelyn, Reinke, Stacey N, Ali, Alishum, Palmer, Debra J, Christophersen, Claus T.

“…Associations between the human gut microbiome and health outcomes continues to be of great interest, although fecal sample collection methods which impact…”
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Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing by Mendez, Kevin M., Pritchard, Leighton, Reinke, Stacey N., Broadhurst, David I.

“…Background A lack of transparency and reporting standards in the scientific community has led to increasing and widespread concerns relating to reproduction…”
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Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD by Naz, Shama, Kolmert, Johan, Yang, Mingxing, Reinke, Stacey N, Kamleh, Muhammad Anas, Snowden, Stuart, Heyder, Tina, Levänen, Bettina, Erle, David J, Sköld, C Magnus, Wheelock, Åsa M, Wheelock, Craig E

“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading cause of mortality and morbidity worldwide. The aim of this study was to…”
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Changes to the Gut Microbiome in Young Children Showing Early Behavioral Signs of Autism by Jones, Jacquelyn, Reinke, Stacey N., Mousavi-Derazmahalleh, Mahsa, Palmer, Debra J., Christophersen, Claus T.

“…The human gut microbiome has increasingly been associated with autism spectrum disorder (ASD), which is a neurological developmental disorder, characterized by…”
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Development of a Liquid Chromatography–High Resolution Mass Spectrometry Metabolomics Method with High Specificity for Metabolite Identification Using All Ion Fragmentation Acquisition by Naz, Shama, Gallart-Ayala, Hector, Reinke, Stacey N, Mathon, Caroline, Blankley, Richard, Chaleckis, Romanas, Wheelock, Craig E

“…High-resolution mass spectrometry (HRMS)-based metabolomics approaches have made significant advances. However, metabolite identification is still a major…”
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Metabolomics analysis identifies different metabotypes of asthma severity by Reinke, Stacey N, Gallart-Ayala, Héctor, Gómez, Cristina, Checa, Antonio, Fauland, Alexander, Naz, Shama, Kamleh, Muhammad Anas, Djukanović, Ratko, Hinks, Timothy S C, Wheelock, Craig E

“…In this study, we sought to determine whether asthma has a metabolic profile and whether this profile is related to disease severity.We characterised the serum…”
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Metabolomics in pulmonary medicine - extracting the most from your data by Reinke, Stacey N, Chaleckis, Romanas, Wheelock, Craig E

“…The metabolome enables unprecedented insight into biochemistry, providing an integrated signature of the genome, transcriptome, proteome and exposome…”
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IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making by Chang, Xiaoqing, Tan, Yu-Mei, Allen, David G, Bell, Shannon, Brown, Paul C, Browning, Lauren, Ceger, Patricia, Gearhart, Jeffery, Hakkinen, Pertti J, Kabadi, Shruti V, Kleinstreuer, Nicole C, Lumen, Annie, Matheson, Joanna, Paini, Alicia, Pangburn, Heather A, Petersen, Elijah J, Reinke, Emily N, Ribeiro, Alexandre J S, Sipes, Nisha, Sweeney, Lisa M, Wambaugh, John F, Wange, Ronald, Wetmore, Barbara A, Mumtaz, Moiz

“…During the past few decades, the science of toxicology has been undergoing a transformation from observational to predictive science. New approach…”
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Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life by Read, James F., Serralha, Michael, Mok, Danny, Holt, Barbara J., Cruickshank, Mark, Karpievitch, Yuliya V., Broadhurst, David I., Sly, Peter D., Strickland, Deborah H., Reinke, Stacey N., Holt, Patrick G., Bosco, Anthony

“…Appropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading…”
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Translational regulation of GPx-1 and GPx-4 by the mTOR pathway by Reinke, Emily N, Ekoue, Dede N, Bera, Soumen, Mahmud, Nadim, Diamond, Alan M

“…Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor…”
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Metabolomics reveals mouse plasma metabolite responses to acute exercise and effects of disrupting AMPK-glycogen interactions by Belhaj, Mehdi R., Lawler, Nathan G., Hawley, John A., Broadhurst, David I., Hoffman, Nolan J., Reinke, Stacey N.

“…Introduction: The AMP-activated protein kinase (AMPK) is a master regulator of energy homeostasis that becomes activated by exercise and binds glycogen, an…”
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Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis by Reinke, SN, Broadhurst, DI, Sykes, BD, Baker, GB, Catz, I, Warren, KG, Power, C

“…Metabolomics enables the provision of sensitive bio-markers of disease. We performed 800 MHz 1H-nuclear magnetic resonance (NMR) spectroscopic analyses of…”
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OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma by Reinke, Stacey N, Galindo-Prieto, Beatriz, Skotare, Tomas, Broadhurst, David I, Singhania, Akul, Horowitz, Daniel, Djukanović, Ratko, Hinks, Timothy S.C, Geladi, Paul, Trygg, Johan, Wheelock, Craig E

“…Integration of multiomics data remains a key challenge in fulfilling the potential of comprehensive systems biology. Multiple-block orthogonal projections to…”
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Ubiquinone-binding Site Mutations in the Saccharomyces cerevisiae Succinate Dehydrogenase Generate Superoxide and Lead to the Accumulation of Succinate by Szeto, Samuel S.W., Reinke, Stacey N., Sykes, Brian D., Lemire, Bernard D.

“…The mitochondrial succinate dehydrogenase (SDH) is an essential component of the electron transport chain and of the tricarboxylic acid cycle. Also known as…”
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Analysis of the emission profile in organic light-emitting devices by Perucco, B, Reinke, N A, Rezzonico, D, Moos, M, Ruhstaller, B

“…In this paper, numerical algorithms for extraction of optoelectronic material and device parameters in organic light-emitting devices (OLEDs) are presented and…”
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Selenium supplementation affects broiler growth performance, meat yield and feather coverage by Choct, M, Naylor, A.J, Reinke, N

“…1. Selenium (Se) is an essential part of numerous selenoproteins, most of which are involved in the antioxidant system of the body. It is also required by…”
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A comparative evaluation of the generalised predictive ability of eight machine learning algorithms across ten clinical metabolomics data sets for binary classification by Mendez, Kevin M., Reinke, Stacey N., Broadhurst, David I.

“…Introduction Metabolomics is increasingly being used in the clinical setting for disease diagnosis, prognosis and risk prediction. Machine learning algorithms…”
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Procedure for Experimental Data Assessment for Numerical Solver Validation in the Context of Model based Prediction of Powder Coating Patterns by B Siyahhan, M Boldrini, S Hauri, N Reinke, G Boiger

“…In the scope of this study an experimental powder coating setup is designed and the method to extract statistically significant trends from the data generated…”
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