Search Results - "REILLY, Paul"

The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients: The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy) by REILLY, Paul A, LEHR, Thorsten, HAERTTER, Sebastian, CONNOLLY, Stuart J, YUSUF, Salim, EIKELBOOM, John W, EZEKOWITZ, Michael D, NEHMIZ, Gerhard, SUSAN WANG, WALLENTIN, Lars

“…The goal of this study was to analyze the impact of dabigatran plasma concentrations, patient demographics, and aspirin (ASA) use on frequencies of ischemic…”
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Newly Identified Events in the RE-LY Trial by Reilly, Paul A, Connolly, Stuart J, Yusuf, Salim, Ezekowitz, Michael D, Wallentin, Lars

“…To the Editor: We wish to update our article about the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial (Sept. 17, 2009, issue). 1…”
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Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial by Wallentin, Lars, Prof, Yusuf, Salim, Prof, Ezekowitz, Michael D, Prof, Alings, Marco, MD, Flather, Marcus, MD, Franzosi, Maria Grazia, PhD, Pais, Prem, Prof, Dans, Antonio, Prof, Eikelboom, John, MD, Oldgren, Jonas, MD, Pogue, Janice, PhD, Reilly, Paul A, PhD, Yang, Sean, MSc, Connolly, Stuart J, Prof

“…Summary Background Effectiveness and safety of warfarin is associated with the time in therapeutic range (TTR) with an international normalised ratio (INR) of…”
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Idarucizumab for Dabigatran Reversal — Full Cohort Analysis by Pollack, Charles V, Reilly, Paul A, van Ryn, Joanne, Eikelboom, John W, Glund, Stephan, Bernstein, Richard A, Dubiel, Robert, Huisman, Menno V, Hylek, Elaine M, Kam, Chak-Wah, Kamphuisen, Pieter W, Kreuzer, Jörg, Levy, Jerrold H, Royle, Gordon, Sellke, Frank W, Stangier, Joachim, Steiner, Thorsten, Verhamme, Peter, Wang, Bushi, Young, Laura, Weitz, Jeffrey I

“…Idarucizumab was 100% effective in reversing the anticoagulant effect of dabigatran among 300 patients with uncontrolled bleeding (median time to bleeding…”
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Concomitant Use of Antiplatelet Therapy with Dabigatran or Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial by DANS, Antonio L, CONNOLLY, Stuart J, YUSUF, Salim, WALLENTIN, Lars, YANG, Sean, NAKAMYA, Juliet, BRUECKMANN, Martina, EZEKOWITZ, Michael, OLDGREN, Jonas, EIKELBOOM, John W, REILLY, Paul A

“…The Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial showed that dabigatran etexilate 150 mg BID was superior and dabigatran etexilate…”
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Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial by Diener, Hans-Christoph, Prof, Connolly, Stuart J, Prof, Ezekowitz, Michael D, Prof, Wallentin, Lars, Prof, Reilly, Paul A, PhD, Yang, Sean, MSc, Xavier, Denis, MD, Di Pasquale, Giuseppe, Prof, Yusuf, Salim, Prof

“…Summary Background In the Randomised Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial, dabigatran reduced occurrence of both stroke and…”
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Idarucizumab for Dabigatran Reversal by Pollack, Charles V, Reilly, Paul A, Eikelboom, John, Glund, Stephan, Verhamme, Peter, Bernstein, Richard A, Dubiel, Robert, Huisman, Menno V, Hylek, Elaine M, Kamphuisen, Pieter W, Kreuzer, Jörg, Levy, Jerrold H, Sellke, Frank W, Stangier, Joachim, Steiner, Thorsten, Wang, Bushi, Kam, Chak-Wah, Weitz, Jeffrey I

“…Intravenous idarucizumab, an antibody fragment of a human antibody specific for dabigatran, produced rapid reversal of the anticoagulant effect in patients…”
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Intracranial Hemorrhage in Atrial Fibrillation Patients During Anticoagulation With Warfarin or Dabigatran: The RE-LY Trial by HART, Robert G, DIENER, Hans-Christoph, SEAN YANG, CONNOLLY, Stuart J, WALLENTIN, Lars, REILLY, Paul A, EZEKOWITZ, Michael D, YUSUF, Salim

“…Intracranial hemorrhage is the most devastating complication of anticoagulation. Outcomes associated with different sites of intracranial bleeding occurring…”
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Comparison of Dabigatran and Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulant Therapy) by Ezekowitz, Michael D, Nagarakanti, Rangadham, Noack, Herbert, Brueckmann, Martina, Litherland, Claire, Jacobs, Mark, Clemens, Andreas, Reilly, Paul A, Connolly, Stuart J, Yusuf, Salim, Wallentin, Lars

“…BACKGROUND:The RE-LY trial (Randomized Evaluation of Long-Term Anticoagulant Therapy) compared dabigatran 150 and 110 mg twice daily with warfarin in 18 113…”
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Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation: A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy by HIJAZI, Ziad, OLDGREN, Jonas, WALLENTIN, Lars, ANDERSSON, Ulrika, CONNOLLY, Stuart J, EZEKOWITZ, Michael D, HOHNLOSER, Stefan H, REILLY, Paul A, VINEREANU, Dragos, SIEGBAHN, Agneta, YUSUF, Salim

“…Cardiac biomarkers are strong predictors of adverse outcomes in several patient populations. We evaluated the prevalence of elevated troponin I and N-terminal…”
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Variations in Cause and Management of Atrial Fibrillation in a Prospective Registry of 15 400 Emergency Department Patients in 46 Countries: The RE-LY Atrial Fibrillation Registry by Oldgren, Jonas, Healey, Jeff S, Ezekowitz, Michael, Commerford, Patrick, Avezum, Alvaro, Pais, Prem, Zhu, Jun, Jansky, Petr, Sigamani, Alben, Morillo, Carlos A, Liu, Lisheng, Damasceno, Albertino, Grinvalds, Alex, Nakamya, Juliet, Reilly, Paul A, Keltai, Katalin, Van Gelder, Isabelle C, Yusufali, Afzal Hussein, Watanabe, Eiichi, Wallentin, Lars, Connolly, Stuart J, Yusuf, Salim

“…BACKGROUND—Atrial fibrillation (AF) is the most common sustained arrhythmia; however, little is known about patients in a primary care setting from high-,…”
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Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation: A RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) Trial Analysis by Hijazi, Ziad, Hohnloser, Stefan H, Oldgren, Jonas, Andersson, Ulrika, Connolly, Stuart J, Eikelboom, John W, Ezekowitz, Michael D, Reilly, Paul A, Siegbahn, Agneta, Yusuf, Salim, Wallentin, Lars

“…BACKGROUND—Renal impairment increases the risk of stroke and bleeding in patients with atrial fibrillation. In the Randomized Evaluation of Long-Term…”
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Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial by Glund, Stephan, Dr, Stangier, Joachim, PhD, Schmohl, Michael, PhD, Gansser, Dietmar, PhD, Norris, Stephen, PhD, van Ryn, Joanne, PhD, Lang, Benjamin, Dipl Math oec, Ramael, Steven, MD, Moschetti, Viktoria, MD, Gruenenfelder, Fredrik, DVM, Reilly, Paul, PhD, Kreuzer, Jörg, Prof

“…Summary Background Idarucizumab is a monoclonal antibody fragment that binds dabigatran with high affinity in a 1:1 molar ratio. We investigated the safety,…”
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Changes in Renal Function in Patients With Atrial Fibrillation: An Analysis From the RE-LY Trial by Böhm, Michael, Ezekowitz, Michael D, Connolly, Stuart J, Eikelboom, John W, Hohnloser, Stefan H, Reilly, Paul A, Schumacher, Helmut, Brueckmann, Martina, Schirmer, Stephan H, Kratz, Mario T, Yusuf, Salim, Diener, Hans-Christoph, Hijazi, Ziad, Wallentin, Lars

“…Vitamin K-dependent factors protect against vascular and renovascular calcification, and vitamin K antagonists may be associated with a decreased glomerular…”
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Easy data, same old platforms? A systematic review of digital activism methodologies by Özkula, Suay M., Reilly, Paul J., Hayes, Jenny

“…Burgess and Bruns (2015) have linked the computational turn in social media research to an increase in the number of studies focussing exclusively on 'easy…”
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Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran by Pollack, Jr, Charles V, Reilly, Paul A, Bernstein, Richard, Dubiel, Robert, Eikelboom, John, Glund, Stephan, Huisman, Menno V, Hylek, Elaine, Kam, Chak-Wah, Kamphuisen, Pieter W, Kreuzer, Joerg, Levy, Jerrold H, Sellke, Frank, Stangier, Joachim, Steiner, Thorsten, Wang, Bushi, Weitz, Jeffrey I

“…Idarucizumab, a Fab fragment directed against dabigatran, produced rapid and complete reversal of the anticoagulation effect of dabigatran in animals and in…”
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Additive Archaeology: An Alternative Framework for Recontextualising Archaeological Entities by Reilly, Paul

“…Additive manufacturing poses a number of challenges to conventional understandings of materiality, including the so-called archaeological record. In…”
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Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation by Aulin, Julia, MD, Siegbahn, Agneta, MD, PhD, Hijazi, Ziad, MD, PhD, Ezekowitz, Michael D., MB, ChB, Andersson, Ulrika, MSc, Connolly, Stuart J., MD, Huber, Kurt, MD, PhD, Reilly, Paul A., PhD, Wallentin, Lars, MD, PhD, Oldgren, Jonas, MD, PhD

“…Background Inflammation has been associated with cardiovascular disease and the burden of atrial fibrillation (AF). In this study we evaluate inflammatory…”
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A global perspective on cadmium pollution and toxicity in non-occupationally exposed population by Satarug, Soisungwan, Baker, Jason R, Urbenjapol, Supanee, Haswell-Elkins, Melissa, Reilly, Paul E.B, Williams, David J, Moore, Michael R

“…Cadmium is a non-essential element that has high rates of soil to plant transference compared with other non-essential elements, and certain plant species…”
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Dabigatran Versus Warfarin in Patients With Atrial Fibrillation: An Analysis of Patients Undergoing Cardioversion by NAGARAKANTI, Rangadham, EZEKOWITZ, Michael D, REILLY, Paul A, YUSUF, Salim, CONNOLLY, Stuart J, OLDGREN, Jonas, YANG, Sean, CHERNICK, Michael, AIKENS, Timothy H, FLAKER, Greg, BRUGADA, Josep, KAMENSKY, Gabriel, PAREKH, Amit

“…The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial compared dabigatran 110 mg BID (D110) and 150 mg BID (D150) with warfarin for…”
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