Search Results - "REHNCRONA, Stig"
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Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain
Published in Proceedings of the National Academy of Sciences - PNAS (07-06-2016)“…Clinical trials using cells derived from embryonic ventral mesencephalon have shown that transplanted dopaminergic neurons can survive and function in the long…”
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Strategic alterations of posture are delayed in Parkinson’s disease patients during deep brain stimulation
Published in Scientific reports (07-12-2021)“…Parkinson’s disease (PD) is characterized by rigidity, akinesia, postural instability and tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN)…”
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Comparison of accuracy and precision between frame-based and frameless stereotactic navigation for deep brain stimulation electrode implantation
Published in Stereotactic and functional neurosurgery (01-01-2007)“…The accuracy and precision of frameless neuronavigation as compared to conventional frame-based stereotaxy for implantation of deep brain stimulation (DBS)…”
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Deep brain stimulation in the subthalamic nuclei alters postural alignment and adaptation in Parkinson's disease
Published in PloS one (14-12-2021)“…Parkinson's disease (PD) can produce postural abnormalities of the standing body position such as kyphosis. We investigated the effects of PD, deep brain…”
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Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients
Published in The Journal of clinical investigation (01-03-2015)“…BACKGROUND. Recombinant human PDGF-BB (rhPDGF-BB) reduces Parkinsonian symptoms and increases dopamine transporter (DAT) binding in several animal models of…”
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Multicenter study on deep brain stimulation in Parkinson's disease: An independent assessment of reported adverse events at 4 years
Published in Movement disorders (15-02-2008)“…Ongoing adverse events (AEs) at 4‐years postsurgery in 69 patients with advanced Parkinson′s disease (PD) who received deep brain stimulation (DBS) of the…”
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Exploring the effects of deep brain stimulation and vision on tremor in Parkinson's disease - benefits from objective methods
Published in Journal of neuroengineering and rehabilitation (25-04-2020)“…Tremor is a cardinal symptom of Parkinson's disease (PD) that may cause severe disability. As such, objective methods to determine the exact characteristics of…”
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Long-term efficacy of thalamic deep brain stimulation for tremor: Double-blind assessments
Published in Movement disorders (01-02-2003)“…Thalamic deep brain stimulation (DBS) is proven to suppress tremor in Parkinson's disease (PD) and essential tremor (ET). However, there are few reports on its…”
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Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
Published in Nature neuroscience (01-12-1999)“…Synaptic dopamine release from embryonic nigral transplants has been monitored in the striatum of a patient with Parkinson's disease using [11C]-raclopride…”
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Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
Published in Annals of neurology (01-11-2000)“…Intrastriatal transplantation of dopaminergic neurones aims to repair the selective loss of nigrostriatal projections and the consequent dysfunction of…”
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The effects of high frequency subthalamic stimulation on balance performance and fear of falling in patients with Parkinson's disease
Published in Journal of neuroengineering and rehabilitation (30-04-2009)“…Balance impairment is one of the most distressing symptoms in Parkinson's disease (PD) even with pharmacological treatment (levodopa). A complementary…”
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Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease
Published in Annals of neurology (01-02-1994)“…Two patients with idiopathic Parkinson's disease (Patients 3 and 4 in our series) were followed up to 3 years after grafting of human embryonic dopamine-rich…”
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Grafts of Fetal Dopamine Neurons Survive and Improve Motor Function in Parkinson's Disease
Published in Science (American Association for the Advancement of Science) (02-02-1990)“…Neural transplantation can restore striatal dopaminergic neurotransmission in animal models of Parkinson's disease. It has now been shown that mesencephalic…”
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Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports
Published in JAMA neurology (01-01-2014)“…Recent advances in stem cell technologies have rekindled an interest in the use of cell replacement strategies for patients with Parkinson disease. This study…”
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Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants
Published in Science translational medicine (30-06-2010)“…Troublesome involuntary movements in the absence of dopaminergic medication, so-called off-medication dyskinesias, are a serious adverse effect of fetal neural…”
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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Published in Nature medicine (01-05-2008)“…Two subjects with Parkinson's disease who had long-term survival of transplanted fetal mesencephalic dopaminergic neurons (11-16 years) developed…”
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Long-term outcome in patients with suspected normal pressure hydrocephalus
Published in Neurosurgery (01-02-2007)“…To evaluate the outcome of patients with suspected normal pressure hydrocephalus at 6 months and 5 years after shunt surgery. Seventy-five patients (mean age,…”
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Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
Published in Movement disorders (15-06-2010)“…We previously reported the occurrence of Lewy bodies in grafted human fetal mesencephalic neurons in two patients with Parkinson's disease. Here, we have used…”
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Spectral analysis of body movement during deep brain stimulation in Parkinson’s disease
Published in Gait & posture (01-05-2021)“…•We processed movement into three bands: 0−4 Hz, 4−7 Hz and 7−25 Hz.•There was altered postural strategy in patients with PD with deep brain stimulation.•There…”
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Long-term results of a multicenter study on subthalamic and pallidal stimulation in Parkinson's disease
Published in Movement disorders (15-04-2010)“…We report the 5 to 6 year follow‐up of a multicenter study of bilateral subthalamic nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation…”
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