Search Results - "REGLODI, DORA"
-
1
The Neuroprotective and Biomarker Potential of PACAP in Human Traumatic Brain Injury
Published in International journal of molecular sciences (28-01-2020)“…Traumatic brain injury remains a growing public health concern and represents the greatest contributor to death and disability globally among all…”
Get full text
Journal Article -
2
Novel tactics for neuroprotection in Parkinson's disease: Role of antibiotics, polyphenols and neuropeptides
Published in Progress in neurobiology (01-08-2017)“…Parkinson's disease is a progressive neurodegenerative disorder characterized by the degeneration of midbrain nigral dopaminergic neurons. Although its…”
Get full text
Journal Article -
3
The Neuropeptide Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is Protective in Inflammation and Oxidative Stress-Induced Damage in the Kidney
Published in International journal of molecular sciences (07-10-2019)“…Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide with a widespread distribution throughout the entire body including…”
Get full text
Journal Article -
4
Effects of Pacap on Schwann Cells: Focus on Nerve Injury
Published in International journal of molecular sciences (03-11-2020)“…Schwann cells, the most abundant glial cells of the peripheral nervous system, represent the key players able to supply extracellular microenvironment for…”
Get full text
Journal Article -
5
Effects of Pituitary Adenylate Cyclase Activating Polypeptide on Cell Death
Published in International journal of molecular sciences (29-04-2022)“…Pituitary adenylate cyclase activating polypeptide (PACAP) was first isolated as a hypothalamic peptide based on its efficacy to increase adenylate cyclase…”
Get full text
Journal Article -
6
PACAP and NAP: Effect of Two Functionally Related Peptides in Diabetic Retinopathy
Published in Journal of molecular neuroscience (01-08-2021)“…Pituitary adenylate cyclase-activating polypeptide (PACAP) is a peptide involved in physio-pathological processes of the eye. It exerts multiple effects…”
Get full text
Journal Article -
7
Role of endocrine PACAP in age-related diseases
Published in Frontiers in endocrinology (Lausanne) (09-03-2023)“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a conserved neuropeptide, which confers diverse anti-aging endocrine and paracrine/autocrine…”
Get full text
Journal Article -
8
-
9
Effects of PACAP Deficiency on Immune Dysfunction and Peyer's Patch Integrity in Adult Mice
Published in International journal of molecular sciences (01-10-2024)“…PACAP (pituitary adenylate cyclase activating polypeptide) is a widespread neuropeptide with cytoprotective and anti-inflammatory effects. It plays a role in…”
Get full text
Journal Article -
10
PACAP suppresses dry eye signs by stimulating tear secretion
Published in Nature communications (27-06-2016)“…Dry eye syndrome is caused by a reduction in the volume or quality of tears. Here, we show that pituitary adenylate cyclase-activating polypeptide (PACAP)-null…”
Get full text
Journal Article -
11
Stability Test of PACAP in Eye Drops
Published in Journal of molecular neuroscience (01-08-2021)“…PACAP is a neuropeptide with widespread distribution and diverse biological functions. It has strong cytoprotective effects mediated mainly through specific…”
Get full text
Journal Article -
12
Female reproductive functions of the neuropeptide PACAP
Published in Frontiers in endocrinology (Lausanne) (20-09-2022)“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide originally isolated as a hypothalamic peptide. It has a widespread distribution in…”
Get full text
Journal Article -
13
PACAP Modulates the Autophagy Process in an In Vitro Model of Amyotrophic Lateral Sclerosis
Published in International journal of molecular sciences (22-04-2020)“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of complex etiology leading to motor neuron degeneration. Many gene alterations…”
Get full text
Journal Article -
14
Review on PACAP-Induced Transcriptomic and Proteomic Changes in Neuronal Development and Repair
Published in International journal of molecular sciences (29-03-2018)“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with widespread occurrence and diverse biological effects. Among its several…”
Get full text
Journal Article -
15
Protective Effects of Pituitary Adenylate-Cyclase-Activating Polypeptide on Retinal Vasculature and Molecular Responses in a Rat Model of Moderate Glaucoma
Published in International journal of molecular sciences (01-09-2023)“…Despite the high probability of glaucoma-related blindness, its cause is not fully understood and there is no efficient therapeutic strategy for…”
Get full text
Journal Article -
16
Optimization of an Ischemic Retinopathy Mouse Model and the Consequences of Hypoxia in a Time-Dependent Manner
Published in International journal of molecular sciences (01-08-2024)“…The retina is one of the highest metabolically active tissues with a high oxygen consumption, so insufficient blood supply leads to visual impairment. The…”
Get full text
Journal Article -
17
Protective effects of PACAP in ischemia
Published in Journal of headache and pain (02-03-2018)“…Pituitary adenylate cyclase activating polypeptide (PACAP) is an ubiquitous peptide involved, among others, in neurodevelopment, neuromodulation,…”
Get full text
Journal Article -
18
PACAP Protects Against Inflammatory-Mediated Toxicity in Dopaminergic SH-SY5Y Cells: Implication for Parkinson’s Disease
Published in Neurotoxicity research (01-10-2014)“…There has been a growing recognition of the role of neuroinflammation caused by microglia-exaggerated release of inflammatory mediators in the pathogenesis of…”
Get full text
Journal Article -
19
Retinoprotective Effects of PACAP Eye Drops in Microbead-Induced Glaucoma Model in Rats
Published in International journal of molecular sciences (17-08-2021)“…Glaucoma is associated with increased intraocular pressure (IOP), causing the apoptosis of retinal ganglion cells (RGCs) and the loss of their axons leading to…”
Get full text
Journal Article -
20
Protective Effects of PACAP in Peripheral Organs
Published in Frontiers in endocrinology (Lausanne) (14-07-2020)“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide widely distributed in the nervous system, where it exerts strong neuroprotective…”
Get full text
Journal Article