Search Results - "REGER, N"

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors by Kerkar, Sid P, Goldszmid, Romina S, Muranski, Pawel, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Reger, Robert N, Leonardi, Anthony J, Morgan, Richard A, Wang, Ena, Marincola, Francesco M, Trinchieri, Giorgio, Rosenberg, Steven A, Restifo, Nicholas P

“…Solid tumors are complex masses with a local microenvironment, or stroma, that supports tumor growth and progression. Among the diverse tumor-supporting…”
Get full text

Adoptively transferred effector cells derived from naïve rather than central memory CD8⁺ T cells mediate superior antitumor immunity by Hinrichs, Christian S, Borman, Zachary A, Cassard, Lydie, Gattinoni, Luca, Spolski, Rosanne, Yu, Zhiya, Sanchez-Perez, Luis, Muranski, Pawel, Kern, Steven J, Logun, Carol, Palmer, Douglas C, Ji, Yun, Reger, Robert N, Leonard, Warren J, Danner, Robert L, Rosenberg, Steven A, Restifo, Nicholas P

“…Effector cells derived from central memory CD8⁺ T cells were reported to engraft and survive better than those derived from effector memory populations,…”
Get full text

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion by Allan, David S.J., Chakraborty, Mala, Waller, Giacomo C., Hochman, Michael J., Poolcharoen, Akkapon, Reger, Robert N., Childs, Richard W.

“…Transduction of primary human natural killer (NK) cells with lentiviral vectors has historically been challenging. We sought to evaluate multiple parameters to…”
Get full text

Quantification of circulating TCR-engineered T cells targeting a human endogenous retrovirus post-adoptive transfer using nanoplate digital PCR by Barisic, Stefan, Cherkasova, Elena, Nadal, Rosa, Tian, Xin, Chen, Long, Parrizzi, Angelina, Reger, Robert N., Scurti, Gina M., Nishimura, Michael I., Childs, Richard W.

“…In vivo expansion of genetically modified T cells in cancer patients following adoptive transfer has been linked to both anti-tumor activity and…”
Get full text

Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature by Muranski, Pawel, Borman, Zachary A., Kerkar, Sid P., Klebanoff, Christopher A., Ji, Yun, Sanchez-Perez, Luis, Sukumar, Madhusudhanan, Reger, Robert N., Yu, Zhiya, Kern, Steven J., Roychoudhuri, Rahul, Ferreyra, Gabriela A., Shen, Wei, Durum, Scott K., Feigenbaum, Lionel, Palmer, Douglas C., Antony, Paul A., Chan, Chi-Chao, Laurence, Arian, Danner, Robert L., Gattinoni, Luca, Restifo, Nicholas P.

“…Th17 cells have been described as short lived, but this view is at odds with their capacity to trigger protracted damage to normal and transformed tissues. We…”
Get full text

Development and evaluation of TiAl sheet structures for hypersonic applications by Draper, S.L., Krause, D., Lerch, B., Locci, I.E., Doehnert, B., Nigam, R., Das, G., Sickles, P., Tabernig, B., Reger, N., Rissbacher, K.

“…A cooperative program between the National Aeronautics and Space Administration (NASA), the Austrian Space Agency (ASA), Pratt & Whitney, Engineering…”
Get full text

Experimental Investigation of Mechanical Properties of Metallic Hollow Sphere Structures by Friedl, O., Motz, C., Peterlik, H., Puchegger, S., Reger, N., Pippan, R.

“…Metallic foam was fabricated from 316L stainless steel spheres, where the bonding of the spheres was achieved by a sintering process. The mechanical behavior…”
Get full text

Augmentation of NK Cell Proliferation and Anti-tumor Immunity by Transgenic Expression of Receptors for EPO or TPO by Chanswangphuwana, Chantiya, Allan, David S.J., Chakraborty, Mala, Reger, Robert N., Childs, Richard W.

“…Many investigational adoptive immunotherapy regimens utilizing natural killer (NK) cells require the administration of interleukin-2 (IL-2) or IL-15, but these…”
Get full text

Cube textured nickel alloy tapes as substrates for YBa2Cu3O7-δ-COATED conductors by DE BOER, B, EICKEMEYER, J, REGER, N, FERNANDEZ G.-R, L, RICHTER, J, HOLZAPFEL, B, SCHULTZ, L, PRUSSEIT, W, BERBERICH, P

Get full text

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells by Ji, Yun, Pos, Zoltan, Rao, Mahadev, Klebanoff, Christopher A, Yu, Zhiya, Sukumar, Madhusudhanan, Reger, Robert N, Palmer, Douglas C, Borman, Zachary A, Muranski, Pawel, Wang, Ena, Schrump, David S, Marincola, Francesco M, Restifo, Nicholas P, Gattinoni, Luca

“…The molecular basis of CD8 + memory is still being delineated. Gattinoni et al . show that the DNA-binding inhibitor Id3 is critical for the formation of…”
Get full text

Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts by KERKAR, Sid P, MURANSKI, Pawel, MORGAN, Richard A, GATTINONI, Luca, ROSENBERG, Steven A, TRINCHIERI, Giorgio, RESTIFO, Nicholas P, KAISER, Andrew, BONI, Andrea, SANCHEZ-PEREZ, Luis, ZHIYA YU, PALMER, Douglas C, REGER, Robert N, BORMAN, Zachary A, LING ZHANG

“…T-cell-based immunotherapies can be effective in the treatment of large vascularized tumors, but they rely on adoptive transfer of substantial numbers (…”
Get full text

RNA-Seq Analysis Reveals CCR5 as a Key Target for CRISPR Gene Editing to Regulate In Vivo NK Cell Trafficking by Levy, Emily R, Clara, Joseph A, Reger, Robert N, Allan, David S J, Childs, Richard W

“…A growing number of natural killer (NK) cell-based immunotherapy trials utilize ex vivo expansion to grow and activate allogenic and autologous NK cells prior…”
Get full text

A Novel Method to Study the in Vivo Trafficking and Homing of Adoptively Transferred NK Cells in Rhesus Macaques and Humans by Davidson-Moncada, Jan, Sato, Noriko, Hoyt, Robert F, Reger, Robert N, Thomas, Marvin, Clevenger, Randy, Metzger, Mark E., Donahue, Robert E., Eclarinal, Philip C, Szajek, Lawrence, Griffiths, Gary L, Dunbar, Cynthia E., Choyke, Peter, Childs, Richard

“…Adoptive transfer of allogeneic or autologous natural killer (NK) cells is now being developed for therapy of both hematological and solid malignancies. The…”
Get full text

Documenting stress in caregivers of transplantation patients: initial evidence of HPA dysregulation by Bevans, Margaret F, Ross, Alyson, Wehrlen, Leslie, Klagholz, Stephen D, Yang, Li, Childs, Richard, Flynn, Sharon L, Remaley, Alan T, Krumlauf, Michael, Reger, Robert N, Wallen, Gwenyth R, Shamburek, Robert, Pacak, Karel

“…There is growing evidence linking caregiver stress with an increased risk for morbidity and mortality. While the emotional and practical burden experienced by…”
Get more information

Allogeneic transplantation using CD34+ selected peripheral blood progenitor cells combined with non‐mobilized donor T cells for refractory severe aplastic anaemia by Purev, Enkhtsetseg, Tian, Xin, Aue, Georg, Pantin, Jeremy, Vo, Phuong, Shalabi, Reem, Reger, Robert N., Cook, Lisa, Ramos, Catalina, Cho, Elena, Worthy, Tat'yana, Khuu, Hanh, Stroncek, David, Young, Neal S., Childs, Richard W.

“…Summary Allogeneic haematopoietic stem cell transplantation is curative for severe aplastic anaemia (SAA) unresponsive to immunosuppressive therapy. To reduce…”
Get full text

Grain boundary networks in Y123 coated conductors: Formation, properties and simulation by Holzapfel, B., Fernandez, L., Schindler, F., de Boer, B., Reger, N., Eickemeyer, J., Berberich, P., Prusseit, W.

“…The grain boundary (GB) network in biaxially textured YBa/sub 2/Cu/sub 3/O/sub x/ (Y123) coated conductors is the key to their transport properties and…”
Get full text

Strengthening of biaxially textured Ni-alloys as substrates for YBCO tape conductors by de Boer, B, Sarma, V, Reger, N, Eickemeyer, J, Holzapfel, B

“…Highly biaxially textured Ni tapes have been strengthened by introducing Al 2O 3 particles with internal oxidation. The tape strength could be increased by a…”
Get full text

An experimental study of the main involved parameters in the epitaxial growth of CeO2 buffer layers on nickel tapes by Arranz, M.A., Holzapfel, B., Reger, N., Eickemeyer, J., Schultz, L.

“…In order to investigate the optimal conditions for highly oriented and epitaxial buffer layers on Ni based tapes, authors have grown several sequences of CeO2…”
Get full text

Biaxially textured Ni-alloy tapes as substrates for buffer and YBCO film growth by Boer, B.de, Reger, N., Fernandez G.-R., L., Eickemeyer, J., Holzapfel, B., Schultz, L., Prusseit, W., Berberich, P.

“…Impurities in Ni processed by cold rolling and annealing for the purpose of producing a cube textured substrate for YBCO film deposition (RABiTS) often evoke…”
Get full text

Biaxially textured Ni-alloy tapes as substrates for buffer and Y-Ba-Cu-O film growth by de Boer, B., Reger, N., Fernandez G.R., L., Eickemeyer, J., Berberich, P., Prusseit, W., Holzapfel, B., Schultz, L.

“…Highly cube ({001} ) textured Ni- and Ni-alloy tapes are produced by heavy cold rolling and recrystallisation annealing. Due to impurities in Ni, abnormal…”
Get full text