Search Results - "REESINK, Henk W"

Identification of a Novel HBV Encoded miRNA Using Next Generation Sequencing by Loukachov, Vladimir, van Dort, Karel A., Jansen, Louis, Reesink, Henk W., Kootstra, Neeltje A.

“…Hepatitis B Virus (HBV) encoded miRNAs were previously described and suggested to play a role in HBV replication and pathogenesis. In this study we aim to…”
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Hepatitis B core related antigen in relation to intrahepatic and circulating viral markers, before and after combination therapy by Erken, Robin, Zaaijer, Hans L., Willemse, Sophie B., Bakker, Ed, Takkenberg, Bart B., Reesink, Henk W., Kootstra, Neeltje A.

“…Covalently closed circular (ccc)DNA acts as a viral reservoir in the liver of patients with a chronic hepatitis B (CHB) infection and can only be quantified in…”
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Identification of Liver and Plasma microRNAs in Chronic Hepatitis B Virus infection by Loukachov, Vladimir V., van Dort, Karel A., Maurer, Irma, Takkenberg, R. Bart, de Niet, Anniki, Reesink, Henk W., Willemse, Sophie B., Kootstra, Neeltje A.

“…Background and Aims With current standard of care a functional cure for Chronic Hepatitis B (CHB) is only achieved in 1-3% of patients and therefore novel…”
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Transfusion-transmitted infectious diseases by Allain, Jean-Pierre, Stramer, Susan L., Carneiro-Proietti, A.B.F., Martins, M.L., Lopes da Silva, S.N., Ribeiro, M., Proietti, F.A., Reesink, Henk W.

“…A spectrum of blood-borne infectious agents is transmitted through transfusion of infected blood donated by apparently healthy and asymptomatic blood donors…”
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Cellular Immune Responses during High-Dose Interferon-α Induction Therapy for Hepatitis C Virus Infection by Barnes, Eleanor, Gelderblom, Huub C., Humphreys, Isla, Semmo, Nasser, Reesink, Henk W., Beld, Marcel G. H. M., van Lier, René A. W., Klenerman, Paul

“…BackgroundThe effect that high-dose interferon (IFN)–α induction therapy for hepatitis C virus (HCV) infection has on cellular immune responses is currently…”
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ABT-450, Ritonavir, Ombitasvir, and Dasabuvir Achieves 97% and 100% Sustained Virologic Response With or Without Ribavirin in Treatment-Experienced Patients With HCV Genotype 1b Infection by Andreone, Pietro, Colombo, Massimo G, Enejosa, Jeffrey V, Koksal, Iftihar, Ferenci, Peter, Maieron, Andreas, Müllhaupt, Beat, Horsmans, Yves, Weiland, Ola, Reesink, Henk W, Rodrigues, Lino, Hu, Yiran B, Podsadecki, Thomas, Bernstein, Barry

“…Background & Aims The interferon-free regimen of ABT-450 (a protease inhibitor), ritonavir, ombitasvir (an NS5A inhibitor), dasabuvir (a non-nucleoside…”
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Factor XIII Val34Leu mutation accelerates the development of fibrosis in patients with chronic hepatitis B and C by Dik, Kathelijne, de Bruijne, Joep, Takkenberg, R. Bart, Roelofs, Joris J., Tempelmans, Marjan J., Dijkgraaf, Marcel G. W., Gelderblom, Huub C., Reesink, Henk W., Meijers, Joost C. M., Jansen, Peter L., Levi, Marcel

“…Aim:  There is considerable variation in liver fibrosis stage and progression to cirrhosis among patients with chronic hepatitis B (CHB) or C (CHC)…”
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Optimization of Real-Time PCR Assay for Rapid and Sensitive Detection of Eubacterial 16S Ribosomal DNA in Platelet Concentrates by MOHAMMADI, Tamimount, REESINK, Henk W, VANDENBROUCKE-GRAULS, Christina M. J. E, SAVELKOUL, Paul H. M

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Removal of contaminating DNA from commercial nucleic acid extraction kit reagents by Mohammadi, Tamimount, Reesink, Henk W., Vandenbroucke-Grauls, Christina M.J.E., Savelkoul, Paul H.M.

“…Due to contamination of DNA extraction reagents, false-positive results can occur when applying broad-range real-time PCR based on bacterial 16 S rDNA…”
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Rapid HCV-RNA Decline With Once Daily TMC435: A Phase I Study in Healthy Volunteers and Hepatitis C Patients by Reesink, Henk W, Fanning, Gregory C, Farha, Khalid Abou, Weegink, Christine, Van Vliet, André, van 't Klooster, Gerben, Lenz, Oliver, Aharchi, Fatima, Mariën, Kris, Van Remoortere, Pieter, de Kock, Herman, Broeckaert, Fabrice, Meyvisch, Paul, Van Beirendonck, Els, Simmen, Kenneth, Verloes, René

“…Background & Aims The search for targeted anti-hepatitis C virus (HCV) drugs is driven by the adverse effect profile and limited efficacy of the current…”
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Non-invasive evaluation of liver fibrosis: a comparison of ultrasound-based transient elastography and MR elastography in patients with viral hepatitis B and C by Bohte, Anneloes E., de Niet, Annikki, Jansen, Louis, Bipat, Shandra, Nederveen, Aart J., Verheij, Joanne, Terpstra, Valeska, Sinkus, Ralph, van Nieuwkerk, Karin M. J., de Knegt, Rob J., Baak, Bert C., Jansen, Peter L. M., Reesink, Henk W., Stoker, Jaap

“…Objective To compare the diagnostic accuracy of TE and MRE and establish cutoff levels and diagnostic strategies for both techniques, enabling selection of…”
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Evolution of hepatitis C virus quasispecies during repeated treatment with the NS3/4A protease inhibitor telaprevir by Susser, Simone, Flinders, Mathieu, Reesink, Henk W, Zeuzem, Stefan, Lawyer, Glenn, Ghys, Anne, Van Eygen, Veerle, Witek, James, De Meyer, Sandra, Sarrazin, Christoph

“…In treating hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections, the rapid reselection of resistance-associated variants (RAVs) is well…”
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Viral Hepatitis C Therapy: Pharmacokinetic and Pharmacodynamic Considerations by de Kanter, Clara T. M. M., Drenth, Joost P. H., Arends, Joop E., Reesink, Henk W., van der Valk, Marc, de Knegt, Robert J., Burger, David M.

“…Chronic hepatitis C is a global health problem. To prevent or reduce complications, the hepatitis C virus (HCV) infection needs to be eradicated. There have…”
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Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C by REISER, Markus, HINRICHSEN, Holger, BENHAMOU, Yves, REESINK, Henk W, WEDEMEYER, Heiner, AVENDANO, Cristina, RIBA, Neus, YONG, Chan-Loi, NEHMIZ, Gerhard, STEINMANN, Gerhard G

“…BILN-2061, a specific and potent peptidomimetic inhibitor of the HCV NS3 protease, has recently been shown to markedly lower serum hepatitis C virus (HCV)-RNA…”
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Retreatment with telaprevir combination therapy in hepatitis C patients with well‐characterized prior treatment response by Muir, Andrew J., Poordad, Fred F., McHutchison, John G., Shiffman, Mitchell L., Berg, Thomas, Ferenci, Peter, Heathcote, E. Jenny, Pawlotsky, Jean‐Michel, Zeuzem, Stefan, Reesink, Henk W., Dusheiko, Geoffrey, Martin, Emily C., George, Shelley, Kauffman, Robert S., Adda, Nathalie

“…Retreatment with peginterferon alpha and ribavirin (PR) offers a limited chance of sustained virologic response (SVR) in patients who did not achieve SVR with…”
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Low-level HCV viraemia after initial response during antiviral therapy : transcription-mediated amplification predicts treatment failure by GELDERBLOM, Huub C, REESINK, Henk W, BELD, Marcel G. H. M, WEEGINK, Christine J, JANSEN, Peter L. M, DIJKGRAAF, Marcel G. W, ZAAIJER, Hans L

“…In chronic hepatitis C patients with an initial virological response (IVR) during antiviral therapy (that is, HCV RNA becomes negative before week 16 of…”
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Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors by Nielen, Markus M. J., van Schaardenburg, Dirkjan, Reesink, Henk W., van de Stadt, Rob J., van der Horst‐Bruinsma, Irene E., de Koning, Margret H. M. T., Habibuw, Moud R., Vandenbroucke, Jan P., Dijkmans, Ben A. C.

“…Objective Autoantibodies have been demonstrated in single serum samples from healthy subjects up to 10 years before they developed rheumatoid arthritis (RA)…”
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929e PEARL-II: Randomized Phase 3 Trial of Interferon-Free, 12-Week Regimen of ABT-450/r/ABT-267, ABT-333 With or Without Ribavirin in Hepatitis C Virus Genotype 1b-Infected, Treatment-Experienced Patients by Andreone, Pietro, Colombo, Massimo, Enejosa, Jeffrey V, Koksal, Iftihar, Ferenci, Peter, Maieron, Andreas, Müllhaupt, Beat, Horsmans, Yves, Weiland, Ola, Reesink, Henk W, Jr, Lino Rodrigues, Hu, Yiran B, Podsadecki, Thomas

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Bone metabolism is altered in preclinical rheumatoid arthritis by van Schaardenburg, Dirkjan, Nielen, Markus M J, Lems, Willem F, Twisk, Jos W R, Reesink, Henk W, van de Stadt, Rob J, van der Horst-Bruinsma, Irene E, de Koning, Margret H M T, Habibuw, Moud R, Dijkmans, Ben A C

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Antiviral activity of narlaprevir combined with ritonavir and pegylated interferon in chronic hepatitis C patients by de Bruijne, Joep, Bergmann, Jilling F., Reesink, Henk W., Weegink, Christine J., Molenkamp, Richard, Schinkel, Janke, Tong, Xiao, Li, Jing, Treitel, Michelle A., Hughes, Eric A., van Lier, Jan Jaap, van Vliet, Andre A., Janssen, Harry L. A., de Knegt, Robert J.

“…Narlaprevir (SCH 900518) is a potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 3 serine protease that is primarily metabolized by the…”
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