Search Results - "REES, Lesley"

Dialysis Accelerates Medial Vascular Calcification in Part by Triggering Smooth Muscle Cell Apoptosis by SHROFF, Rukshana C, MCNAIR, Rosamund, SHANAHAN, Catherine M, FIGG, Nichola, SKEPPER, Jeremy N, SCHURGERS, Leon, GUPTA, Ashmeet, HIORNS, Melanie, DONALD, Ann E, DEANFIELD, John, REES, Lesley

“…Vascular calcification is associated with increased morbidity and mortality in stage V chronic kidney disease, yet its early pathogenesis and initiating…”
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Chronic Mineral Dysregulation Promotes Vascular Smooth Muscle Cell Adaptation and Extracellular Matrix Calcification by SHROFF, Rukshana C, MCNAIR, Rosamund, SKEPPER, Jeremy N, FIGG, Nichola, SCHURGERS, Leon J, DEANFIELD, John, REES, Lesley, SHANAHAN, Catherine M

“…In chronic kidney disease (CKD) vascular calcification occurs in response to deranged calcium and phosphate metabolism and is characterized by vascular smooth…”
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The virtues of vitamin D—but how much is too much? by Shroff, Rukshana, Knott, Craig, Rees, Lesley

“…Vitamin D deficiency is common in healthy adults and children as well as in the chronic kidney disease (CKD) population. What was once a disease of…”
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A Bimodal Association of Vitamin D Levels and Vascular Disease in Children on Dialysis by SHROFF, Rukshana, EGERTON, Martyn, BRIDEL, Michala, SHAH, Vanita, DONALD, Ann E, COLE, Tim J, HIORNS, Melanie P, DEANFIELD, John E, REES, Lesley

“…In addition to its classical role in calcium-phosphate homeostasis, vitamin D has anti-inflammatory effects that may influence vascular disease. This study…”
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Mineral metabolism and vascular damage in children on dialysis by SHROFF, Rukshana C, DONALD, Ann E, REES, Lesley, HIORNS, Melanie P, WATSON, Alan, FEATHER, Sally, MILFORD, David, ELLINS, Elizabeth A, STORRY, Clare, RIDOUT, Deborah, DEANFIELD, John

“…Cardiovascular disease is increasingly recognized as a life-limiting problem in young patients with chronic kidney disease, but there are few studies in…”
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Growth in Very Young Children Undergoing Chronic Peritoneal Dialysis by REES, Lesley, AZOCAR, Marta, VAN HOECK, Koen, SECKER, Donna, ZUROWSKA, Aleksandra, RÖNNHOLM, Kai, BOUTS, Antonia H. M, STEWART, Heather, ARICETA, Gema, RANCHIN, Bruno, WARADY, Bradley A, SCHAEFER, Franz, BORZYCH, Dagmara, WATSON, Alan R, BÜSCHER, Anja, EDEFONTI, Alberto, BILGE, Ilmay, ASKENAZI, David, LEOZAPPA, Giovanna, GONZALES, Claudia

“…Very young children with chronic kidney disease often have difficulty maintaining adequate nutrition, which contributes to the high prevalence of short stature…”
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Long-Term Outcome of Infants with Severe Chronic Kidney Disease by Mekahli, Djalila, Shaw, Vanessa, Ledermann, Sarah E, Rees, Lesley

“…In 2000, we reported the outcome of 101 children with a GFR <20 ml/min per 1.73 m2 at 0.3 yr of age (range 0.0 to 1.5 yr). Long-term data on such young…”
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Ergocalciferol Supplementation in Children with CKD Delays the Onset of Secondary Hyperparathyroidism: A Randomized Trial by Shroff, Rukshana, Wan, Mandy, Gullett, Ambrose, Ledermann, Sarah, Shute, Rachel, Knott, Craig, Wells, David, Aitkenhead, Helen, Manickavasagar, Bahee, van't Hoff, William, Rees, Lesley

“…Vitamin D deficiency is an important contributor to the development of hyperparathyroidism and is independently associated with cardiovascular and bone…”
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Can vitamin D slow down the progression of chronic kidney disease? by Shroff, Rukshana, Wan, Mandy, Rees, Lesley

“…Pharmacological blockade of the renin–angiotensin–aldosterone system (RAAS) is the cornerstone of renoprotective therapy, and the reduction of persistent RAAS…”
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The bone and mineral disorder of children undergoing chronic peritoneal dialysis by Borzych, Dagmara, Rees, Lesley, Ha, Il Soo, Chua, Annabelle, Valles, Patricia G., Lipka, Maria, Zambrano, Pedro, Ahlenstiel, Thurid, Bakkaloglu, Sevcan A., Spizzirri, Ana P., Lopez, Laura, Ozaltin, Fatih, Printza, Nikoleta, Hari, Pankaj, Klaus, Günter, Bak, Mustafa, Vogel, Andrea, Ariceta, Gema, Yap, Hui Kim, Warady, Bradley A., Schaefer, Franz

“…The mineral and bone disorder of chronic kidney disease remains a challenging complication in pediatric end-stage renal disease. Here, we assessed symptoms,…”
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The post-transplant lymphoproliferative disorder-a literature review by Shroff, Rokshana, Rees, Lesley

“…The Epstein-Barr virus (EBV)-induced post-transplant lymphoproliferative disorder (PTLD) affects 1%-10% of all paediatric renal transplant recipients. This is…”
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Protein energy wasting; what is it and what can we do to prevent it? by Rees, Lesley

“…Some children with declining height and BMI SDS fail to respond to optimisation of nutritional intake. As well as poor growth, they have muscle wasting and…”
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Circulating angiopoietin-2 is a marker for early cardiovascular disease in children on chronic dialysis by Shroff, Rukshana C, Price, Karen L, Kolatsi-Joannou, Maria, Todd, Alexandra F, Wells, David, Deanfield, John, Johnson, Richard J, Rees, Lesley, Woolf, Adrian S, Long, David A

“…Cardiovascular disease (CVD) is increasingly recognised as a complication of childhood chronic kidney disease (CKD) even in the absence of diabetes and…”
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Phosphate binders in CKD: chalking out the differences by Rees, Lesley, Shroff, Rukshana C.

“…Plasma phosphate levels are important in the evolution of hyperparathyroidism and ectopic calcification in chronic kidney disease (CKD). Although dietary…”
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Assessment of dialysis adequacy: beyond urea kinetic measurements by Rees, Lesley

“…Adequacy of dialysis is a term that has been used for many years based on measurement of small solute clearance using urea and creatinine. This has been shown…”
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Simultaneous Kidney and Parathyroid Transplantation in the Management of Genetic Hypoparathyroidism in a Child by Vallant, Natalie, Sinha, Manish D., Cheung, Moira, Ware, Nick, Jones, Helen, Buck, Jackie, Boffa, Catherine, Irving, Melita, Carroll, Paul V., Hubbard, Johnathan, Gökmen, Refik, Rees, Lesley, Gogalniceanu, Petrut, Kessaris, Nicos

“…Genetically determined hypoparathyroidism can lead to life-threatening episodes of hypocalcemia and, more rarely, to end-stage kidney disease at a young age…”
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Pediatric Myocardial Stunning Underscores the Cardiac Toxicity of Conventional Hemodialysis Treatments by Hothi, Daljit K., Rees, Lesley, Marek, Jan, Burton, James, McIntyre, Christopher W.

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Growth hormone therapy in children with CKD after more than two decades of practice by Rees, Lesley

“…This review focuses on the evidence for the efficacy and safety of recombinant human growth hormone (rhGH) therapy in children with all stages of chronic…”
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Iodine excess in children with kidney disease: are we missing hypothyroidism? by Rees, Lesley

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Renal replacement therapies in neonates: Issues and ethics by Rees, Lesley

“…Abstract Chronic irreversible kidney disease requiring dialysis is rare in the neonate. Many such neonates are diagnosed following antenatal ultrasound with…”
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