Search Results - "REED, Sharon L"

Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens by Leber, Amy L, Everhart, Kathy, Balada-Llasat, Joan-Miquel, Cullison, Jillian, Daly, Judy, Holt, Sarah, Lephart, Paul, Salimnia, Hossein, Schreckenberger, Paul C, DesJarlais, Sharon, Reed, Sharon L, Chapin, Kimberle C, LeBlanc, Lindsay, Johnson, J Kristie, Soliven, Nicole L, Carroll, Karen C, Miller, Jo-Anne, Dien Bard, Jennifer, Mestas, Javier, Bankowski, Matthew, Enomoto, Tori, Hemmert, Andrew C, Bourzac, Kevin M

“…Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to minimize morbidity and mortality. Comprehensive testing of…”
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Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent by Capparelli, Edmund V, Bricker-Ford, Robin, Rogers, M John, McKerrow, James H, Reed, Sharon L

“…Under an NIH priority to identify new drugs to treat class B parasitic agents, we performed high-throughput screens, which identified the activity of auranofin…”
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Point‐of‐care diagnosis of invasive aspergillosis in non‐neutropenic patients: Aspergillus Galactomannan Lateral Flow Assay versus Aspergillus‐specific Lateral Flow Device test in bronchoalveolar lavage by Jenks, Jeffrey D., Mehta, Sanjay R., Taplitz, Randy, Aslam, Saima, Reed, Sharon L., Hoenigl, Martin

“…Summary Background We compared new Aspergillus Galactomannan Lateral Flow Assay with the newly formatted Aspergillus‐specific Lateral Flow device tests for the…”
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Cysteine proteases in protozoan parasites by Siqueira-Neto, Jair L, Debnath, Anjan, McCall, Laura-Isobel, Bernatchez, Jean A, Ndao, Momar, Reed, Sharon L, Rosenthal, Philip J

“…Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins,…”
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New drug target in protozoan parasites: the role of thioredoxin reductase by Andrade, Rosa M, Reed, Sharon L

“…Amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. It is treated primarily with metronidazole,…”
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A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia by TEJMAN-YARDEN, Noa, MIYAMOTO, Yukiko, LEITSCH, David, SANTINI, Jennifer, DEBNATH, Anjan, GUT, Jiri, MCKERROW, James H, REED, Sharon L, ECKMANN, Lars

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19 by Suhandynata, Raymond T, Hoffman, Melissa A, Kelner, Michael J, McLawhon, Ronald W, Reed, Sharon L, Fitzgerald, Robert L

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus…”
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A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target by Debnath, Anjan, Parsonage, Derek, Andrade, Rosa M, He, Chen, Cobo, Eduardo R, Hirata, Ken, Chen, Steven, García-Rivera, Guillermina, Orozco, Esther, Martínez, Máximo B, Gunatilleke, Shamila S, Barrios, Amy M, Arkin, Michelle R, Poole, Leslie B, McKerrow, James H, Reed, Sharon L

“…Entamoeba histolytica causes human amebiasis. Although antibiotic therapy for this infection exists, there are limited treatment options for this potentially…”
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X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action by Parsonage, Derek, Sheng, Fang, Hirata, Ken, Debnath, Anjan, McKerrow, James H., Reed, Sharon L., Abagyan, Ruben, Poole, Leslie B., Podust, Larissa M.

“…The anti-arthritic gold-containing drug Auranofin is lethal to the protozoan intestinal parasite Entamoeba histolytica, the causative agent of human amebiasis,…”
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Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis by Chaparro, Juan D, Cheng, Timmy, Tran, Uyen Phuong, Andrade, Rosa M, Brenner, Sara B T, Hwang, Grace, Cohn, Shara, Hirata, Ken, McKerrow, James H, Reed, Sharon L

“…Although toxoplasmosis is one of the most common parasitic infections worldwide, therapeutic options remain limited. Cathepsins, proteases that play key roles…”
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Auranofin is highly efficacious against Toxoplasma gondii in vitro and in an in vivo experimental model of acute toxoplasmosis by Andrade, Rosa M, Chaparro, Juan D, Capparelli, Edmund, Reed, Sharon L

“…The mainstay of toxoplasmosis treatment targets the folate biosynthetic pathways and has not changed for the last 50 years. The activity of these…”
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Under the Radar: Balamuthia Amebic Encephalitis by Schuster, Frederick L., Yagi, Shigeo, Gavali, Shilpa, Michelson, David, Raghavan, Ravi, Blomquist, Ingrid, Glastonbury, Christine, Bollen, Andrew W., Scharnhorst, David, Reed, Sharon L., Kuriyama, Steve, Visvesvara, Govinda S., Glaser, Carol A.

“…Background. We present data from 9 years (1999–2008) of tests for Balamuthia mandrillaris, an agent of amebic encephalitis that were conducted as part of the…”
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Entamoeba histolytica Induces Intestinal Cathelicidins but Is Resistant to Cathelicidin-Mediated Killing by Cobo, Eduardo R, He, Chen, Hirata, Ken, Hwang, Grace, Tran, UyenPhuong, Eckmann, Lars, Gallo, Richard L, Reed, Sharon L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Predictors of Failure from Primary Therapy for Giardiasis in San Diego: A Single Institution Retrospective Review by Debnath, Anjan, Reed, Sharon L, Morris, Sheldon R

“…This study aimed to determine the presence of giardiasis among HIV patients in San Diego, the rate of failure of metronidazole treatment, and factors…”
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Automated Real-Time Collection of Pathogen-Specific Diagnostic Data: Syndromic Infectious Disease Epidemiology by Meyers, Lindsay, Ginocchio, Christine C, Faucett, Aimie N, Nolte, Frederick S, Gesteland, Per H, Leber, Amy, Janowiak, Diane, Donovan, Virginia, Dien Bard, Jennifer, Spitzer, Silvia, Stellrecht, Kathleen A, Salimnia, Hossein, Selvarangan, Rangaraj, Juretschko, Stefan, Daly, Judy A, Wallentine, Jeremy C, Lindsey, Kristy, Moore, Franklin, Reed, Sharon L, Aguero-Rosenfeld, Maria, Fey, Paul D, Storch, Gregory A, Melnick, Steve J, Robinson, Christine C, Meredith, Jennifer F, Cook, Camille V, Nelson, Robert K, Jones, Jay D, Scarpino, Samuel V, Althouse, Benjamin M, Ririe, Kirk M, Malin, Bradley A, Poritz, Mark A

“…Health care and public health professionals rely on accurate, real-time monitoring of infectious diseases for outbreak preparedness and response. Early…”
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Cathepsin Cs Are Key for the Intracellular Survival of the Protozoan Parasite, Toxoplasma gondii by Que, Xuchu, Engel, Juan C., Ferguson, David, Wunderlich, Annette, Tomavo, Stanislas, Reed, Sharon L.

“…Cysteine proteases play key roles in apicomplexan invasion, organellar biogenesis, and intracellular survival. We have now characterized five genes encoding…”
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Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection by Schooley, Robert T, Biswas, Biswajit, Gill, Jason J, Hernandez-Morales, Adriana, Lancaster, Jacob, Lessor, Lauren, Barr, Jeremy J, Reed, Sharon L, Rohwer, Forest, Benler, Sean, Segall, Anca M, Taplitz, Randy, Smith, Davey M, Kerr, Kim, Kumaraswamy, Monika, Nizet, Victor, Lin, Leo, McCauley, Melanie D, Strathdee, Steffanie A, Benson, Constance A, Pope, Robert K, Leroux, Brian M, Picel, Andrew C, Mateczun, Alfred J, Cilwa, Katherine E, Regeimbal, James M, Estrella, Luis A, Wolfe, David M, Henry, Matthew S, Quinones, Javier, Salka, Scott, Bishop-Lilly, Kimberly A, Young, Ry, Hamilton, Theron

“…Widespread antibiotic use in clinical medicine and the livestock industry has contributed to the global spread of multidrug-resistant (MDR) bacterial…”
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Why Funding for Neglected Tropical Diseases Should Be a Global Priority by Reed, Sharon L, McKerrow, James H

“…Abstract Neglected tropical diseases affect >1 billion of the world's poorest persons. Control programs range from near-elimination (dracunculiasis) to…”
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Rare mould infections caused by Mucorales, Lomentospora prolificans and Fusarium, in San Diego, CA: the role of antifungal combination therapy by Jenks, Jeffrey D., Reed, Sharon L., Seidel, Danila, Koehler, Philipp, Cornely, Oliver A., Mehta, Sanjay R., Hoenigl, Martin

“…•Retrospective analysis of patients with non-Aspergillus invasive mould infections (IMIs) at a US university medical centre.•IMIs occurred in patients with a…”
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Bronchoalveolar lavage Aspergillus Galactomannan lateral flow assay versus Aspergillus-specific lateral flow device test for diagnosis of invasive pulmonary Aspergillosis in patients with hematological malignancies by Jenks, Jeffrey D., Mehta, Sanjay R., Taplitz, Randy, Law, Nancy, Reed, Sharon L., Hoenigl, Martin

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