Search Results - "REDEGELD, F. A. M"
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Hepatic, intestinal and renal transport of 1-naphthol-β-D-glucuronide in mutant rats with hereditary-conjugated hyperbilirubinemia
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-1989)“…Recently, a mutant rat strain was described with a genetic defect for the biliary excretion of organic anions (TR-rats). To determine the possible…”
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2
LFA-1, and not Mac-1, is crucial for the development of hyperreactivity in a murine model of nonallergic asthma
Published in American journal of respiratory and critical care medicine (01-02-1996)“…In this study, we investigated the importance of the beta 2-integrins for the development of tracheal hyperreactivity in a murine model for nonallergic asthma…”
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3
Determination of glutathione in biological material by flow-injection analysis using an enzymatic recycling reaction
Published in Analytical biochemistry (01-11-1988)“…A sensitive and specific assay for glutathione using a recycling reaction followed by spectrophotometric detection in a flow-injection analysis system is…”
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4
Interaction with cellular ATP generating pathways mediates menadione-induced cytotoxicity in isolated rat hepatocytes
Published in Archives of biochemistry and biophysics (01-07-1990)“…In this study the effect of metabolism of menadione (2-methyl-1,4-naphthoquinone) on ATP generation in isolated rat hepatocytes was investigated…”
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5
Alterations in energy status by menadione metabolism in hepatocytes isolated from fasted and fed rats
Published in Archives of biochemistry and biophysics (15-08-1989)“…The biochemical mechanism of cytotoxicity, induced by the quinoid compound 2-methyl 1,4-naphthoquinone (menadione), was investigated in hepatocytes freshly…”
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6
Nephrotoxicity of the glutathione conjugate of menadione (2-methyl-1, 4-naphthoquinone) in the isolated perfused rat kidney. Role of metabolism by gamma-glutamyltranspeptidase and probenecid-sensitive transport
Published in The Journal of pharmacology and experimental therapeutics (01-02-1991)“…The renal processing of the glutathione conjugate of menadione, 2-methyl-3-S-glutathionyl-1,4-naphthoquinone (thiodione) was studied in the isolated perfused…”
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7
The 3-methylcholanthrene-mimetic effect of 4,4'-dichlorobiphenyl-treatment on phenacetin-induced hepatic glutathione depletion and liver microsomal phenacetin O-deethylation in rats
Published in Toxicology (Amsterdam) (15-12-1986)“…Both 4,4'-dichlorobiphenyl (4,4'-DCB) and 3-methylcholanthrene (3-MC) caused a substantial increase of phenacetin-induced hepatic glutathione (GSH) depletion,…”
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