Search Results - "REDDY, P. ANANTHA"

Emergence and properties of spice and bath salts: A medicinal chemistry perspective by Lewin, Anita H., Seltzman, Herbert H., Carroll, F. Ivy, Mascarella, S. Wayne, Reddy, P. Anantha

“…Over the past five years the number of internet sites advertising “legal highs” has literally exploded, as have user reports of experiences (both pleasurable…”
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α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution by McElhinny, Charles J., Lewin, Anita H., Brieaddy, Larry, Fix, Scott, Imler, Gregory H., Deschamps, Jeffrey, Mascarella, S. Wayne, Seltzman, Herbert H., Anantha Reddy, P., Carroll, F. Ivy

“…The solubility and configurational composition (Z/E) of SL 327, the only systemically administered MEK inhibitor, in physiologically relevant media has been…”
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Designer drugs: a medicinal chemistry perspective by Carroll, F. Ivy, Lewin, Anita H., Mascarella, S. Wayne, Seltzman, Herbert H., Reddy, P. Anantha

“…There are numerous medicinal chemistry reports in the literature describing the pharmacological properties of thousands of narcotics, stimulants,…”
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Designer drugs: a medicinal chemistry perspective (II) by Carroll, F. Ivy, Lewin, Anita H., Mascarella, S. Wayne, Seltzman, Herbert H., Reddy, P. Anantha

“…During 2012–2018, the clandestine manufacture of new psychoactive substances (NPS) designed to circumvent substance control regulations increased exponentially…”
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Synthesis and Characterization of the Selective, Reversible PKC β Inhibitor (9 S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9 H,18 H-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 H)-dione, Ruboxistaurin (LY333531) by Lewin, Anita H, Brieaddy, Larry, Deschamps, Jeffrey R, Imler, Gregory H, Mascarella, S Wayne, Reddy, P Anantha, Carroll, F Ivy

“…The demonstrated role of PKC in  mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and…”
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Caged Naloxone: Synthesis, Characterization, and Stability of 3‑O‑(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX) by Lewin, Anita H, Fix, Scott E, Zhong, Desong, Mayer, Louise D, Burgess, Jason P, Mascarella, S. Wayne, Reddy, P. Anantha, Seltzman, Herbert H, Carroll, F. Ivy

“…The photolabile analogue of the broad-spectrum opioid antagonist naloxone, 3-O-(4,5-dimethoxy-2-nitrophenyl)­carboxymethyl naloxone (also referred to as “caged…”
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Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198) by Chang, Steven D, Brieaddy, Lawrence E, Harvey, Joseph D, Lewin, Anita H, Mascarella, S. Wayne, Seltzman, Herbert H, Reddy, P. Anantha, Decker, Ann M, McElhinny, Charles J, Zhong, Desong, Peterson, Elisha E, Navarro, Hernán A, Bruchas, Michael R, Carroll, F. Ivy

“…The nociceptin/orphanin FQ opioid peptide (NOP) receptor is a widely expressed GPCR involved in the modulation of pain, anxiety, and motor behaviors…”
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Synthesis and pharmacological evaluation of highly potent [Dmt1]DALDA analogs by Reddy, P Anantha, Lewin, Anita H, Schiller, Peter W

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Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation by Carroll, F. Ivy, Lewin, Anita H., Jones, Sean T., Reddy, P. Anantha

“…A fragment condensation solution phase assembly of the naturally occurring CB1 inverse agonist nonapeptides, Pro-Val-Asn-Phe-Lys-Phe/Leu-Leu-Ser-His-OH…”
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Synthesis and Characterization of Peptides Containing a Cyclic Val Adduct of Diepoxybutane, a Possible Biomarker of Human Exposure to Butadiene by Jayaraj, K, Georgieva, Nadia I, Gold, Avram, Sangaiah, R, Koc, Hasan, Klapper, David G, Ball, Louise M, Reddy, Anantha P, Swenberg, James A

“…1,3-Butadiene, a potential human carcinogen widely used in industry, is oxidized by cytochrome P450 to diepoxybutane (DEB), which is the most mutagenic of the…”
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α-Amino(4-aminophenyl)thiomethylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution by McElhinny, Charles J, Lewin, Anita H, Brieaddy, Larry, Fix, Scott, Imler, Gregory H, Deschamps, Jeffrey, Mascarella, S Wayne, Seltzman, Herbert H, Anantha Reddy, P, Carroll, F Ivy

“…Inconsistent results have been reported for the effects of the mitogen-activating extracellular kinase (MEK) inhibitor…”
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C3bi Receptor (Complement Receptor Type 3) Recognizes a Region of Complement Protein C3 Containing the Sequence Arg-Gly-Asp by Wright, Samuel D., Reddy, P. Anantha, Michelle T. C. Jong, Erickson, Bruce W.

“…Human phagocytes express a receptor termed complement receptor type 3 (CR3) that recognizes the complement protein fragment C3bi. We show here that CR3…”
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Synthesis, Characterization and Antimicrobial Activity of Oxovanadium（IV） Complexes of Schiff Base Hydrazones Containing Quinoxaline Moiety by Lakshmi, P. V. Anantha Satyanarayana, T. Reddy, P. Saritha

“…The oxovanadium（IV） complexes of the Schiff base hydrazones, synthesized from 3-hydrazinoquinoxaline-2- one （HQO） with salicylaldehyde （HSHQO）,…”
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Antiviral activity of C-5 substituted tubercidin analogs by Bergstrom, Donald E, Brattesani, Alan J, Ogawa, Mark K, Reddy, P. Anantha, Schweickert, Michael J, Balzarini, Jan, De Clercq, Erik

“…The pyrrolo[2,3-d]pyrimidine nucleoside antibiotics tubercidin, toyocamycin, and sangivamycin and the synthetic analogues 5-chloro-, 5,6-dichloro-, 5-bromo-,…”
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Improved Procedure for the Synthesis of DAMGO by Reddy, P. Anantha, Lewin, Anita H., Carroll, F. Ivy

“…A short and straightforward synthesis of DAMGO is described…”
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Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9S)‑9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro‑9H,18H‑5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4‑h][1,4,13]oxadiazacyclohexadecine-18,20(19H)‑dione, Ruboxistaurin (LY333531) by Lewin, Anita H, Brieaddy, Larry, Deschamps, Jeffrey R, Imler, Gregory H, Mascarella, S. Wayne, Reddy, P. Anantha, Carroll, F. Ivy

“…The demonstrated role of PKCβ in  mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and…”
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A simple formula for the number of rings in a cyclic molecule by Reddy, P. Anantha

“…A simple formula that determines the number of rings from the number of ring atoms and bonds present in a cyclic system…”
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X-Ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent μ-receptor selective opioid agonist. Comparisons with proposed model structures by FLIPPEN-ANDERSON, JUDITH L., DESCHAMPS, JEFFREY R., GEORGE, CLIFFORD, REDDY, P. ANANTHA, LEWIN, ANITA H., BRINE, GEORGE A., SHELDRICK, GEORGE, NIKIFOROVICH, GREGORY

“…Tyr‐D‐Tic‐Phe‐Phe‐NH2 (D‐TIPP), a linear tetrapeptide containing the conformationally restricted Tic residue (tetrahydroisoquinoline‐3‐carboxylic acid), is an…”
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X‐Ray structure of Tyr‐D‐Tic‐Phe‐Phe‐NH 2 (D‐TIPP‐NH 2 ), a highly potent μ‐receptor selective opioid agonist. Comparisons with proposed model structures by FLIPPEN‐ANDERSON, JUDITH L., DESCHAMPS, JEFFREY R., GEORGE, CLIFFORD, REDDY, P. ANANTHA, LEWIN, ANITA H., BRINE, GEORGE A., SHELDRICK, GEORGE, NIKIFOROVICH, GREGORY

“…Tyr‐D‐Tic‐Phe‐Phe‐NH 2 (D‐TIPP), a linear tetrapeptide containing the conformationally restricted Tic residue (tetrahydroisoquinoline‐3‐carboxylic acid), is an…”
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Pyrido[2,3-d]pyrimidine nucleosides. Synthesis via cyclization of C-5-substituted cytidines by Bergstrom, Donald E, Inoue, Hideo, Reddy, P. Anantha

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